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View Full Version : rs12458349 Neanderthal Straight Hair Gene



J Man
06-08-2017, 04:59 PM
According to my new updated 23andme results I have one copy of the ''Neanderthal'' origin allele at rs12458349 which according to them is associated with straight hair. I am TG at rs12458349. Funny thing is though I have wavy/curly hair (when I had hair lol). I can't find much information about rs12458349 and hair type though. I also see though that according to some studies it is associated with kidney disease. Anyone else have similar results at 23andme or know more about rs12458349 and Neanderthal ancestry?

JFWinstone
06-08-2017, 06:36 PM
Before I went bald on top my hair was curly and I'm TT for rs12458349

J Man
06-09-2017, 03:47 AM
Before I went bald on top my hair was curly and I'm TT for rs12458349

Yes the G allele is apparently the Neanderthal version at this SNP.

Roaring
06-09-2017, 11:23 AM
TT and wavy.

msmarjoribanks
07-15-2018, 08:40 PM
Surprised there's not another Neanderthal thread on the 23 and Me forum. This is the first test I took with the conversation piece about Neanderthal ancestry, so I was kind of looking forward to it.

I don't have the straight hair variant (although I do have very straight hair). Nor do I have the height or less likely to sneeze after eating dark chocolate variants (I'm slightly below average in height and don't think I've ever noticed an association between dark chocolate -- which I like -- and sneezing). I do have the variant for less back hair. For the record, I do not have back hair, thank goodness!

Anyway, I have 298 variants, which is apparently more than 82% of 23 and Me testers.

JMcB
07-16-2018, 12:15 AM
I have 277 variants which apparently is more than 52% of 23andMe customers. I’m T/T at rs12458349 and have 0 variants for straight hair, chocolate sneezing, back hair and height. I have two Neanderthal variants on 16 markers and only one on 245 marker. Other than that, I feel pretty normal. :-)

Stephen1986
07-16-2018, 10:25 AM
I have 324 variants whilst my brother has 277.

For rs12458349 both of us have T/T, we both have slightly curly hair. For the others mentioned in this thread -

For the back hair variant, both of us have G/G although my brother has far more back hair than I do.

For height, we're both A/A and G/G and roughly the same height, 5 foot 9.

For dark chocolate (which I've actually just had some of, incidentally), we're both C/C. Neither of us sneeze after eating dark chocolate, although my brother doesn't like dark chocolate anyway.