View Full Version : Scientists find way to silence extra chromosome that causes Down syndrome

07-18-2013, 04:21 AM
In a new study published online in the journal Nature, scientists from University of Massachusetts Medical School (UMMS) harnessed the abilities of a naturally occurring gene called XIST that acts as an “off switch” in X chromosomes. In a culture of stem cells, the researchers were able to repurpose the XIST gene so that instead of silencing X chromosomes, it silenced the extra chromosome 21 instead.

Though the research only shows proof-of-principle for turning off the chromosome – meaning the method is a long way from being utilized in humans – the findings have huge implications for the future of Down syndrome research. Researchers hope this study will pave the way for a better understanding of the disorder’s pathology and potentially help to create new therapeutic targets for therapies.

Read more: http://www.foxnews.com/health/2013/07/17/scientists-find-way-to-silence-extra-chromosome-that-causes-down-syndrome/?intcmp=trending#ixzz2ZMpbqF4j

Scarlet Ibis
07-20-2013, 08:27 AM
Great news; it's nice to see something heartening amidst all the negative things that have been happening in the world lately.