psampson
08-08-2017, 09:28 PM
This section on the ISOGG wiki page on inheritence by descent caught my eye and I'm sure it's a quote with which the forum is familiar
"for the most part IBD blocks longer than 4 cM come from 500 to 1,500 years ago, and blocks longer than 10 cM are within the last 500 years"
I would like to know what to look for when dealing with segment blocks, what do IBD and IBC blocks look like and can phasing a parental kit confirm a genetic link.
The family group I've been researching dates to around 1300 in Suffolk. In the 1400's two branches were quite literally in the next field in North Norfolk to my direct paternal line, and the branch from the 1600's appears in a Gedmatch members gedcom file. With my kit, my sisters kit and my Dad's phased kit I dropped the thresholds to 3cM and 250 SNP's to maximise results and hopefully illustrate my question about segment blocks and came up with the following results.
This Gedmatch member has four kits (I've posted the first two), presumably from close family members and all three of my kits match all four of his kits. Are they IBD or IBC?
My kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 2,270,521 3,302,774 3.4 267
1 17,748,976 18,640,364 3.3 377
4 8,172,699 9,905,396 3.4 351
4 144,715,927 148,600,255 3.2 564
5 174,236,006 175,869,122 3.7 446
5 175,908,000 178,050,226 3.6 492
11 125,947,716 128,021,449 3.7 548
14 88,774,473 89,712,654 3.0 255
15 24,463,770 25,392,155 3.3 251
16 11,779,901 13,225,980 3.9 485
19 54,426,874 55,797,960 3.6 316
20 58,224,844 58,998,640 4.1 254
22 33,818,632 35,125,530 3.0 354
Sister's kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 17,762,277 18,640,378 3.2 392
2 29,582,835 31,421,433 3.3 635
2 193,473,278 199,077,747 3.5 803
5 8,537,044 10,634,830 5.4 696
18 5,976,416 6,858,925 3.9 280
18 59,031,542 60,691,045 3.1 478
22 20,861,074 22,540,725 4.6 283
22 23,933,018 24,936,256 3.2 292
22 33,818,632 35,125,530 3.0 360
Dad's phased kit
Chr Start Location End Location Centimorgans (cM) SNPs
4 8,172,699 9,905,396 3.4 310
11 125,947,716 128,021,449 3.7 512
On this kit, the SNP count is slightly different
My kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 2,270,521 3,302,774 3.4 262
1 17,748,976 18,640,364 3.3 376
4 8,172,699 9,905,396 3.4 348
4 144,715,927 148,600,255 3.2 562
5 174,236,006 175,869,122 3.7 445
5 175,908,000 178,050,226 3.6 490
11 125,947,716 128,021,449 3.7 542
14 88,774,473 89,712,654 3.0 254
15 24,463,770 25,392,155 3.3 251
16 11,779,901 13,225,980 3.9 484
19 54,426,874 55,797,960 3.6 314
20 58,224,844 58,998,640 4.1 253
22 33,818,632 35,125,530 3.0 353
Sister's kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 17,762,277 18,640,378 3.2 396
2 29,582,835 31,421,433 3.3 645
2 193,473,278 199,077,747 3.5 817
5 8,537,044 10,634,830 5.4 702
18 59,031,542 60,691,045 3.1 488
22 23,933,018 24,936,256 3.2 306
Dad's phased kit
Chr Start Location End Location Centimorgans (cM) SNPs
4 8,172,699 9,905,396 3.4 307
11 125,947,716 128,021,449 3.7 506
There are 15 kits with which I, my sister & Dad share matching segments, two of them share 8.8cM & 10.1cM with me & Dad (8.7cM & 9cM)
"for the most part IBD blocks longer than 4 cM come from 500 to 1,500 years ago, and blocks longer than 10 cM are within the last 500 years"
I would like to know what to look for when dealing with segment blocks, what do IBD and IBC blocks look like and can phasing a parental kit confirm a genetic link.
The family group I've been researching dates to around 1300 in Suffolk. In the 1400's two branches were quite literally in the next field in North Norfolk to my direct paternal line, and the branch from the 1600's appears in a Gedmatch members gedcom file. With my kit, my sisters kit and my Dad's phased kit I dropped the thresholds to 3cM and 250 SNP's to maximise results and hopefully illustrate my question about segment blocks and came up with the following results.
This Gedmatch member has four kits (I've posted the first two), presumably from close family members and all three of my kits match all four of his kits. Are they IBD or IBC?
My kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 2,270,521 3,302,774 3.4 267
1 17,748,976 18,640,364 3.3 377
4 8,172,699 9,905,396 3.4 351
4 144,715,927 148,600,255 3.2 564
5 174,236,006 175,869,122 3.7 446
5 175,908,000 178,050,226 3.6 492
11 125,947,716 128,021,449 3.7 548
14 88,774,473 89,712,654 3.0 255
15 24,463,770 25,392,155 3.3 251
16 11,779,901 13,225,980 3.9 485
19 54,426,874 55,797,960 3.6 316
20 58,224,844 58,998,640 4.1 254
22 33,818,632 35,125,530 3.0 354
Sister's kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 17,762,277 18,640,378 3.2 392
2 29,582,835 31,421,433 3.3 635
2 193,473,278 199,077,747 3.5 803
5 8,537,044 10,634,830 5.4 696
18 5,976,416 6,858,925 3.9 280
18 59,031,542 60,691,045 3.1 478
22 20,861,074 22,540,725 4.6 283
22 23,933,018 24,936,256 3.2 292
22 33,818,632 35,125,530 3.0 360
Dad's phased kit
Chr Start Location End Location Centimorgans (cM) SNPs
4 8,172,699 9,905,396 3.4 310
11 125,947,716 128,021,449 3.7 512
On this kit, the SNP count is slightly different
My kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 2,270,521 3,302,774 3.4 262
1 17,748,976 18,640,364 3.3 376
4 8,172,699 9,905,396 3.4 348
4 144,715,927 148,600,255 3.2 562
5 174,236,006 175,869,122 3.7 445
5 175,908,000 178,050,226 3.6 490
11 125,947,716 128,021,449 3.7 542
14 88,774,473 89,712,654 3.0 254
15 24,463,770 25,392,155 3.3 251
16 11,779,901 13,225,980 3.9 484
19 54,426,874 55,797,960 3.6 314
20 58,224,844 58,998,640 4.1 253
22 33,818,632 35,125,530 3.0 353
Sister's kit
Chr Start Location End Location Centimorgans (cM) SNPs
1 17,762,277 18,640,378 3.2 396
2 29,582,835 31,421,433 3.3 645
2 193,473,278 199,077,747 3.5 817
5 8,537,044 10,634,830 5.4 702
18 59,031,542 60,691,045 3.1 488
22 23,933,018 24,936,256 3.2 306
Dad's phased kit
Chr Start Location End Location Centimorgans (cM) SNPs
4 8,172,699 9,905,396 3.4 307
11 125,947,716 128,021,449 3.7 506
There are 15 kits with which I, my sister & Dad share matching segments, two of them share 8.8cM & 10.1cM with me & Dad (8.7cM & 9cM)