JohnHowellsTyrfro
01-06-2018, 09:31 PM
I'm not sure whether people are familiar with this paper which is some years old but maybe contains some interesting data :-
"Conclusions
The detailed sampling scheme used here identified other previously unknown regional patterns in the degree of continental input. For example, the Central-Eastern part of England experienced the most continental introgression. In addition, our inclusion of samples from Wales additional to those of Weale et al. [7] indicates that the transition between England and Wales is somewhat gradual, which was not visible in the samples analyzed in the Weale et al. study
Most studies in human evolution and genetic history have used samples from very few locations, often near major metropolitan areas. Here, we show that detailed samples from multiple small, urban areas with a geographically structured sampling design reveal patterns that could not be detected with typical sampling schemes. For example, analyses of multiple sets have confirmed higher continental input in central England and the northernmost samples (Durness, on the north coast of Scotland and the Scottish Isles) and a lower level of continental introgression in southern England and Lowland Scotland. In addition, multiple sample sets revealed heterogeneity in Wales.
Iberian, French, and Central-Northern Italian populations have been shown to have similar Y chromosome compositions, presumably reflecting their common heritage in the European Palaeolithic [14]; Wilson et al. [4] noted that AMH+1 haplotypes at high frequency are associated with the European Palaeolithic. Here, we note that another haplogroup (I1b2) is found almost exclusively in British populations that have experienced little or no continental genetic input (Tables 1 and S1). Intriguingly, earlier studies have shown that it is present in the Iberian Peninsula at low frequencies (0%–5.4%) and in Sardinia at a significant percentage (35.1%) [9, 14]. This group might be another constituent of the European Palaeolithic.
Finally, we note that forensic analyses based on the Y chromosome generally assume homogeneity of Y chromosome haplotypes throughout most of Europe [17]. Our fine-scale investigation of Y chromosome variation demonstrates appreciable frequency differences of Y chromosome haplotypes over relatively short geographic distances. Haplotype 12 13 11 16 25 11 (hg R1a1) (number of repeats, loci as follows: DYS388, 393, 392, 19, 390, 391) is present at frequencies around 5% in Shetland and Orkney, while it is almost completely absent from the other collections. Similarly, haplotype 14 13 11 14 22 10 (hg IxI1b2) was recorded at 6%–7% in the Central-East English samples, but it was absent from Irish, Welsh, and Scottish populations."
http://dx.doi.org/10.1016/S0960-9822(03)00373-7
This reference is included in another paper on the fine scale genetic structure of the British population:-
"This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to southeastern England from Anglo-Saxon migrations to be under half, and identify the regions not carrying genetic material from these migrations. We suggest significant pre-Roman but post-Mesolithic movement into southeastern England from continental Europe, and show that in non-Saxon parts of the United Kingdom, there exist genetically differentiated subgroups rather than a general ‘Celtic’ population."
https://www.nature.com/articles/nature14230
"Conclusions
The detailed sampling scheme used here identified other previously unknown regional patterns in the degree of continental input. For example, the Central-Eastern part of England experienced the most continental introgression. In addition, our inclusion of samples from Wales additional to those of Weale et al. [7] indicates that the transition between England and Wales is somewhat gradual, which was not visible in the samples analyzed in the Weale et al. study
Most studies in human evolution and genetic history have used samples from very few locations, often near major metropolitan areas. Here, we show that detailed samples from multiple small, urban areas with a geographically structured sampling design reveal patterns that could not be detected with typical sampling schemes. For example, analyses of multiple sets have confirmed higher continental input in central England and the northernmost samples (Durness, on the north coast of Scotland and the Scottish Isles) and a lower level of continental introgression in southern England and Lowland Scotland. In addition, multiple sample sets revealed heterogeneity in Wales.
Iberian, French, and Central-Northern Italian populations have been shown to have similar Y chromosome compositions, presumably reflecting their common heritage in the European Palaeolithic [14]; Wilson et al. [4] noted that AMH+1 haplotypes at high frequency are associated with the European Palaeolithic. Here, we note that another haplogroup (I1b2) is found almost exclusively in British populations that have experienced little or no continental genetic input (Tables 1 and S1). Intriguingly, earlier studies have shown that it is present in the Iberian Peninsula at low frequencies (0%–5.4%) and in Sardinia at a significant percentage (35.1%) [9, 14]. This group might be another constituent of the European Palaeolithic.
Finally, we note that forensic analyses based on the Y chromosome generally assume homogeneity of Y chromosome haplotypes throughout most of Europe [17]. Our fine-scale investigation of Y chromosome variation demonstrates appreciable frequency differences of Y chromosome haplotypes over relatively short geographic distances. Haplotype 12 13 11 16 25 11 (hg R1a1) (number of repeats, loci as follows: DYS388, 393, 392, 19, 390, 391) is present at frequencies around 5% in Shetland and Orkney, while it is almost completely absent from the other collections. Similarly, haplotype 14 13 11 14 22 10 (hg IxI1b2) was recorded at 6%–7% in the Central-East English samples, but it was absent from Irish, Welsh, and Scottish populations."
http://dx.doi.org/10.1016/S0960-9822(03)00373-7
This reference is included in another paper on the fine scale genetic structure of the British population:-
"This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to southeastern England from Anglo-Saxon migrations to be under half, and identify the regions not carrying genetic material from these migrations. We suggest significant pre-Roman but post-Mesolithic movement into southeastern England from continental Europe, and show that in non-Saxon parts of the United Kingdom, there exist genetically differentiated subgroups rather than a general ‘Celtic’ population."
https://www.nature.com/articles/nature14230