View Full Version : U1 General Thread

Johane Derite
02-27-2018, 12:39 AM
I am U1a1a and since there is very little information about this rare mtdna haplogroup online I will open this thread to dump any U1 relevant things that are found.

First I will start with this bronze age U1a1 that appeared in a sample found in Bulgaria, in the Genomic History of Southeast Europe paper:



Johane Derite
02-27-2018, 12:40 AM
Some U1a1 showed up in the Ancestral heterogeneity of ancient Eurasians paper: https://www.biorxiv.org/content/early/2018/02/20/268524.figures-only


Johane Derite
02-27-2018, 12:42 AM
Some more U1 showed up in the "Genetic diversity in Svaneti and its implications for the human settlement of the Highland Caucasus"

paper here: http://onlinelibrary.wiley.com/doi/1...23324/abstract


Johane Derite
02-27-2018, 12:44 AM
4 out of the 80+ female samples are U1 in the "pheonician mtdna from sardinia" here: http://journals.plos.org/plosone/art...l.pone.0190169


Johane Derite
02-27-2018, 12:46 AM
From the U1 mtDNA group at FTDNA: https://www.familytreedna.com/groups...out/background



Johane Derite
02-27-2018, 12:49 AM
From the Swedish Dna project:


Johane Derite
02-27-2018, 12:50 AM
Mtdna pie charts of the regions of Italy (from Ethnopedia). U1 only shows up in North Italy:


Johane Derite
02-27-2018, 12:52 AM
U1 appears twice in the "Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods" : https://www.nature.com/articles/ncomms15694


Johane Derite
02-27-2018, 12:55 AM
U1 appears here in this paper titled Deep common ancestry of Indian and western-Eurasian mitochondrial DNA lineages:



Johane Derite
02-27-2018, 01:04 AM
U1a1a was found in the paper titled "Complete Mitochondrial Genome Sequencing of a Burial from a Romano–Christian Cemetery in the Dakhleh Oasis, Egypt":


"Over time Kellis was a diverse municipality with a combination of pagan, popular magic, and Manichean and Christian beliefs; however, when abandoned near the mid-4th century AD, it was Christian [11]. Kellis was also a sophisticated community attested by the recovery of multiple texts written in Manichaean, Greek, and Coptic [11,12].

Here we report and discuss the preliminary implications of the presence of mitochondrial haplotype U1a1a in Kellis during the Romano-Christian period. Moreover, this result is compared to similar data recently reported from Abusir el-Meleq. Importantly, the ancient population of Kellis represents an uncommon opportunity to characterize a stable community over a period of 400 years. The study of temporal and spatial migration using genetic markers of the K2 population shall increase understanding of the movement patterns of people in antiquity.

Johane Derite
02-27-2018, 01:45 AM
U1 showed up in the Complete Mitochondrial DNA Diversity in Iranians here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080673#pone-0080673-t002

"Besides haplogroup U7, sub-haplogroups U1 and U3 exist at considerable levels in the Iranian populations studied, reaching their highest frequencies in Azeris (9%) and Qashqais (8%), respectively (Table 2). To further assess the variability of haplogroups U1 and U3 found in the mitochondrial gene pool of Iranians we reconstructed the complete mtDNA genome phylogeny based on our and all available published data (Figure S3). It is obvious that these haplogroups have a likely pre-LGM time depth characterized by an overall coalescence time estimates of 38–50 kya and 32–41 kya, respectively, and both have a very distinctive geographic distribution which might be highly informative about the demographic history of the Middle East. Haplogroup U1 presents two basal branches, named - U1a’c and U1b. The latter is found mostly among Europeans, and its estimated age of ∼9–14 kya indicates a postglacial or Late Glacial expansion. Sub-clade U1a’c, with coalescence age estimate of 29–44 kya, is the most represented of U1 clades, and it probably originated in Southwest Asia and split early into three branches. The first branch, U1a, comprises a series of sub-clades (U1a1, U1a2, U1a3, and U1a4) dating to 13–15 kya; it was found across Southwest and South Asia, the Caucasus region and Europe, but at least one lineage within U1a3, which we called here U1a3b, was restricted to Iran. It is characterized by coalescence age estimates of about 10–16 kya thus placing its origin to postglacial or Late Glacial time. It should be noted, that the Persian-specific U1a3a branch is also found in Sardinians, and its estimated age of 8–10 kya points to a long-standing link between them.




03-03-2018, 05:35 AM
Thank you so much, I hope even more research is done on U1 and its descendants in the future as well as more research on its presence in Kerala and South India.

Johane Derite
03-04-2018, 02:00 AM
I hope even more research is done on U1 and its descendants in the future as well as more research on its presence in Kerala and South India.

Me too. It's definitely an important part of the story of the entire U mtdna haplogroups. There is so much U2 that's showing up in many samples in Europe so there is an interesting angle there.

Johane Derite
03-29-2018, 08:12 PM

Johane Derite
03-29-2018, 08:16 PM

Johane Derite
03-29-2018, 08:19 PM
The spread of haplogroup U in west Eurasia with emphasis on branch U3

MtDNA haplogroup U has a prominent West/Central Eurasian geographic range. Its first radiation seems to have occurred in the initial stable warm phase of the MIS 3 interstadial around 50 kya (Table ​(Table1).1). We situated its hypothetical center of expansion in the Dahoguz province of Turkmenistan (Table ​(Table1).1). Next expansions, at around 43 and 33 kya, involved branches U1, U2 and U8 and branches U3, U5 and U6 respectively, and occurred also in periods of relatively mild temperatures. A more recent radiation was dominated by branches U4, U7, U9, and K around 24 kya, just before the Last Glacial Maximum. All these dispersion waves had rather overlapping ranges and preferably southward expansions [42]. Most probably, U1, U3, and U9 went to the Middle East [43–46]; U2i and U7 mainly to South Asia [47–49]; U2e, U4, U5 and U8 to Europe [50–52], and U6 to North Africa and the Mediterranean basin [53–57]. The recent analysis of the mitogenome of a 35 ky-old modern human from Romania, resulted in being a basic U6* sequence, supporting a Paleolithic Eurasian origin for this African lineage [58]. Secondary branches of these haplogroups have revealed more recent and limited human migrations in all the regions mentioned above. Interesting examples are the expansions to the Volga-Ural and Siberian regions of numerous sub-branches of U1a, U2e, U3b, U4, U5b, U7a, U8a and K1a [59, 60], to India of U2i and U7 [61], to Europe of K [62], or in North Africa of U5b [63]. Advances in ancient DNA technology have also made diachronic studies of human populations possible. An outstanding case was the genome sequencing of a 45 ky-old modern human from western Siberia that already carried a basic mtDNA U* lineage [64]. Haplogroups U4, U5, and U8 were the most prominent U lineages in Paleolithic hunter-gatherers of North and Central Europe, but its frequencies drastically diminished with the Neolithic expansion into the area [65–69], while other U lineages as U2, U3, and K, drastically increased in subsequent periods [66, 70–73]. The fact that Neolithic and Bronze Age migrations introduced southern Siberian U5a1b1e and U5b2a2 lineages to Ireland is noteworthy too [74]. It has been also reported the presence of western U2e, U5a and U7 lineages in prehistoric remains as far as the Tarim Basin and Northeast Mongolia [75, 76].

LINK : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442693/

Johane Derite
03-31-2018, 06:16 PM
9 U1 samples showed up in the Central and South Asian DNA Paper:


LINK: https://www.biorxiv.org/content/early/2018/03/31/292581.figures-only

Johane Derite
04-10-2018, 11:32 PM

U Mtdna Phylogeny: http://www.phylotree.org/tree/U.htm

Johane Derite
04-11-2018, 04:35 PM
Upper Casts in South India Tamils have U1a in this paper: "Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms"

LINK: https://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156-9-86#Tab5


Johane Derite
05-17-2018, 08:20 PM
3 new U1's showed up in the "Genetic prehistory of the Greater Caucasus" paper.

Its interesting because they are on the complete other side of the black sea to the Bulgarian U1 that showed up in the recent paper yet not too seperated in time.

LINK: https://www.biorxiv.org/content/early/2018/05/16/322347



12-19-2018, 02:46 PM
Upper Casts in South India Tamils have U1a in this paper: "Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms"

LINK: https://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156-9-86#Tab5


U1a found among Telugu upper caste like Kamma. Many studies don't have resources to recruit from Upper castes so the data is skewed

02-14-2019, 07:51 AM
So interesting, I am a descendent of haplogroup U1a3 and my mother is of Italian descent (though some dna sites can't tell the difference and pegged it Greek). I think we have a substantial Balkan or near eastern influence in our genetics.

02-14-2019, 07:57 AM
^ what do you get using mthap (james lick)? I am U1a3 on 23andme too

08-16-2019, 01:10 PM
I am U1a1b and not only there is not much info, there doesn't seem to be many people with the similar haplogroup.

08-16-2019, 02:51 PM
I am a Nair( non brahmin upper caste ) from the state of Kerala....glad to be part of such a thread!...in the name of the mother!!!

Johane Derite
11-07-2019, 11:58 PM
Two mtdna U1 samples in Rome:

R42 SCR; 67; Isola Sacra Petrous Isola Sacra Roman Imperial Yes 22 - 120 calCE Imperial Rome Imperial 30-min (partial) 473507 Female U1a1
R114 burial 114 Petrous Via Paisiello (Necropoli Salaria) Roman Imperial No 0 - 200 CE Imperial Rome Imperial 30-min (partial) 365698 Female U1b1

from: https://science.sciencemag.org/content/366/6466/708/tab-figures-data

Johane Derite
05-29-2020, 02:12 PM
Three U1 samples in new Anatolia, South Caucasus paper:

ALA017: U1a1d
ART015: U1a1d
IKI024:. U1b1



Johane Derite
05-29-2020, 03:21 PM
Two U1 samples from

A Genetic History of the Near East from an aDNA Time Course Sampling Eight Points in the Past 4,000 Years:

SFI-56 Iron Age II female - U1a1a
SFI-50 Iron Age III female - U1a


Johane Derite
05-29-2020, 03:29 PM
Three U1 samples from the "The Genomic History of the Bronze Age Southern Levant"

I10771 Megiddo_MLBA 1650-1550 BCE U1a1a3
I7184 Yehud_ 2500-2000 BCE U1a1
I6572 Baqah_MLBA 1550-1150 BCE U1a'c