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Johane Derite
02-27-2018, 12:39 AM
I am U1a1a and since there is very little information about this rare mtdna haplogroup online I will open this thread to dump any U1 relevant things that are found.

First I will start with this bronze age U1a1 that appeared in a sample found in Bulgaria, in the Genomic History of Southeast Europe paper:

https://www.nature.com/articles/natu...#extended-data

https://i.imgur.com/9eD0DM4.png

Johane Derite
02-27-2018, 12:40 AM
Some U1a1 showed up in the Ancestral heterogeneity of ancient Eurasians paper: https://www.biorxiv.org/content/early/2018/02/20/268524.figures-only






https://i.imgur.com/OeMbkcP.png

Johane Derite
02-27-2018, 12:42 AM
Some more U1 showed up in the "Genetic diversity in Svaneti and its implications for the human settlement of the Highland Caucasus"

paper here: http://onlinelibrary.wiley.com/doi/1...23324/abstract

https://i.imgur.com/P6nUb7Q.png

Johane Derite
02-27-2018, 12:44 AM
4 out of the 80+ female samples are U1 in the "pheonician mtdna from sardinia" here: http://journals.plos.org/plosone/art...l.pone.0190169



https://i.imgur.com/V8WSAmk.png

Johane Derite
02-27-2018, 12:46 AM
From the U1 mtDNA group at FTDNA: https://www.familytreedna.com/groups...out/background



https://i.imgur.com/grglNmB.png




https://i.imgur.com/i7CpCyt.png

Johane Derite
02-27-2018, 12:49 AM
From the Swedish Dna project:


https://i.imgur.com/bG6PvQF.png

Johane Derite
02-27-2018, 12:50 AM
Mtdna pie charts of the regions of Italy (from Ethnopedia). U1 only shows up in North Italy:

https://i.imgur.com/BbnOkf5.png

Johane Derite
02-27-2018, 12:52 AM
U1 appears twice in the "Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods" : https://www.nature.com/articles/ncomms15694



https://i.imgur.com/Ayik13j.png

Johane Derite
02-27-2018, 12:55 AM
U1 appears here in this paper titled Deep common ancestry of Indian and western-Eurasian mitochondrial DNA lineages:

http://www.cell.com/current-biology/abstract/S0960-9822(00)80057-3





https://i.imgur.com/X31mDlp.png

Johane Derite
02-27-2018, 01:04 AM
U1a1a was found in the paper titled "Complete Mitochondrial Genome Sequencing of a Burial from a Romano–Christian Cemetery in the Dakhleh Oasis, Egypt":

http://www.mdpi.com/2073-4425/8/10/262


"Over time Kellis was a diverse municipality with a combination of pagan, popular magic, and Manichean and Christian beliefs; however, when abandoned near the mid-4th century AD, it was Christian [11]. Kellis was also a sophisticated community attested by the recovery of multiple texts written in Manichaean, Greek, and Coptic [11,12].

Here we report and discuss the preliminary implications of the presence of mitochondrial haplotype U1a1a in Kellis during the Romano-Christian period. Moreover, this result is compared to similar data recently reported from Abusir el-Meleq. Importantly, the ancient population of Kellis represents an uncommon opportunity to characterize a stable community over a period of 400 years. The study of temporal and spatial migration using genetic markers of the K2 population shall increase understanding of the movement patterns of people in antiquity.

Johane Derite
02-27-2018, 01:45 AM
U1 showed up in the Complete Mitochondrial DNA Diversity in Iranians here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080673#pone-0080673-t002



"Besides haplogroup U7, sub-haplogroups U1 and U3 exist at considerable levels in the Iranian populations studied, reaching their highest frequencies in Azeris (9%) and Qashqais (8%), respectively (Table 2). To further assess the variability of haplogroups U1 and U3 found in the mitochondrial gene pool of Iranians we reconstructed the complete mtDNA genome phylogeny based on our and all available published data (Figure S3). It is obvious that these haplogroups have a likely pre-LGM time depth characterized by an overall coalescence time estimates of 38–50 kya and 32–41 kya, respectively, and both have a very distinctive geographic distribution which might be highly informative about the demographic history of the Middle East. Haplogroup U1 presents two basal branches, named - U1a’c and U1b. The latter is found mostly among Europeans, and its estimated age of ∼9–14 kya indicates a postglacial or Late Glacial expansion. Sub-clade U1a’c, with coalescence age estimate of 29–44 kya, is the most represented of U1 clades, and it probably originated in Southwest Asia and split early into three branches. The first branch, U1a, comprises a series of sub-clades (U1a1, U1a2, U1a3, and U1a4) dating to 13–15 kya; it was found across Southwest and South Asia, the Caucasus region and Europe, but at least one lineage within U1a3, which we called here U1a3b, was restricted to Iran. It is characterized by coalescence age estimates of about 10–16 kya thus placing its origin to postglacial or Late Glacial time. It should be noted, that the Persian-specific U1a3a branch is also found in Sardinians, and its estimated age of 8–10 kya points to a long-standing link between them.



https://i.imgur.com/hjphmIG.png





https://i.imgur.com/XKEWWXA.png




https://i.imgur.com/JoKvJdY.png

Tirunelvi
03-03-2018, 05:35 AM
Thank you so much, I hope even more research is done on U1 and its descendants in the future as well as more research on its presence in Kerala and South India.

Johane Derite
03-04-2018, 02:00 AM
I hope even more research is done on U1 and its descendants in the future as well as more research on its presence in Kerala and South India.

Me too. It's definitely an important part of the story of the entire U mtdna haplogroups. There is so much U2 that's showing up in many samples in Europe so there is an interesting angle there.

Johane Derite
03-29-2018, 08:12 PM
https://haplogroup.org/mtdna/rsrs/l123456/l23456/l2346/l346/l34/l3/n/r/u/u1/u1a/u1a1/u1a1a/

Johane Derite
03-29-2018, 08:16 PM
http://www.cagetti.com/Genetics/U1a-haplogroup.html

Johane Derite
03-29-2018, 08:19 PM
The spread of haplogroup U in west Eurasia with emphasis on branch U3

MtDNA haplogroup U has a prominent West/Central Eurasian geographic range. Its first radiation seems to have occurred in the initial stable warm phase of the MIS 3 interstadial around 50 kya (Table ​(Table1).1). We situated its hypothetical center of expansion in the Dahoguz province of Turkmenistan (Table ​(Table1).1). Next expansions, at around 43 and 33 kya, involved branches U1, U2 and U8 and branches U3, U5 and U6 respectively, and occurred also in periods of relatively mild temperatures. A more recent radiation was dominated by branches U4, U7, U9, and K around 24 kya, just before the Last Glacial Maximum. All these dispersion waves had rather overlapping ranges and preferably southward expansions [42]. Most probably, U1, U3, and U9 went to the Middle East [43–46]; U2i and U7 mainly to South Asia [47–49]; U2e, U4, U5 and U8 to Europe [50–52], and U6 to North Africa and the Mediterranean basin [53–57]. The recent analysis of the mitogenome of a 35 ky-old modern human from Romania, resulted in being a basic U6* sequence, supporting a Paleolithic Eurasian origin for this African lineage [58]. Secondary branches of these haplogroups have revealed more recent and limited human migrations in all the regions mentioned above. Interesting examples are the expansions to the Volga-Ural and Siberian regions of numerous sub-branches of U1a, U2e, U3b, U4, U5b, U7a, U8a and K1a [59, 60], to India of U2i and U7 [61], to Europe of K [62], or in North Africa of U5b [63]. Advances in ancient DNA technology have also made diachronic studies of human populations possible. An outstanding case was the genome sequencing of a 45 ky-old modern human from western Siberia that already carried a basic mtDNA U* lineage [64]. Haplogroups U4, U5, and U8 were the most prominent U lineages in Paleolithic hunter-gatherers of North and Central Europe, but its frequencies drastically diminished with the Neolithic expansion into the area [65–69], while other U lineages as U2, U3, and K, drastically increased in subsequent periods [66, 70–73]. The fact that Neolithic and Bronze Age migrations introduced southern Siberian U5a1b1e and U5b2a2 lineages to Ireland is noteworthy too [74]. It has been also reported the presence of western U2e, U5a and U7 lineages in prehistoric remains as far as the Tarim Basin and Northeast Mongolia [75, 76].

LINK : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442693/

Johane Derite
03-31-2018, 06:16 PM
9 U1 samples showed up in the Central and South Asian DNA Paper:

https://i.imgur.com/0VlUMnw.png



LINK: https://www.biorxiv.org/content/early/2018/03/31/292581.figures-only

Johane Derite
04-10-2018, 11:32 PM
https://i.imgur.com/QUjFYZw.png























U Mtdna Phylogeny: http://www.phylotree.org/tree/U.htm

Johane Derite
04-11-2018, 04:35 PM
Upper Casts in South India Tamils have U1a in this paper: "Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms"


LINK: https://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156-9-86#Tab5




https://i.imgur.com/JgCPFvA.png

Johane Derite
05-17-2018, 08:20 PM
3 new U1's showed up in the "Genetic prehistory of the Greater Caucasus" paper.

Its interesting because they are on the complete other side of the black sea to the Bulgarian U1 that showed up in the recent paper yet not too seperated in time.


LINK: https://www.biorxiv.org/content/early/2018/05/16/322347

https://i.imgur.com/ekDO5Fa.png


https://i.imgur.com/P5tjuR4.png

tipirneni
12-19-2018, 02:46 PM
Upper Casts in South India Tamils have U1a in this paper: "Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms"


LINK: https://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156-9-86#Tab5




https://i.imgur.com/JgCPFvA.png

U1a found among Telugu upper caste like Kamma. Many studies don't have resources to recruit from Upper castes so the data is skewed

Chelsaroo650
02-14-2019, 07:51 AM
So interesting, I am a descendent of haplogroup U1a3 and my mother is of Italian descent (though some dna sites can't tell the difference and pegged it Greek). I think we have a substantial Balkan or near eastern influence in our genetics.

Mandoos
02-14-2019, 07:57 AM
^ what do you get using mthap (james lick)? I am U1a3 on 23andme too

Mak
08-16-2019, 01:10 PM
I am U1a1b and not only there is not much info, there doesn't seem to be many people with the similar haplogroup.

vishankar
08-16-2019, 02:51 PM
I am a Nair( non brahmin upper caste ) from the state of Kerala....glad to be part of such a thread!...in the name of the mother!!!

Johane Derite
11-07-2019, 11:58 PM
Two mtdna U1 samples in Rome:

R42 SCR; 67; Isola Sacra Petrous Isola Sacra Roman Imperial Yes 22 - 120 calCE Imperial Rome Imperial 30-min (partial) 473507 Female U1a1
R114 burial 114 Petrous Via Paisiello (Necropoli Salaria) Roman Imperial No 0 - 200 CE Imperial Rome Imperial 30-min (partial) 365698 Female U1b1

from: https://science.sciencemag.org/content/366/6466/708/tab-figures-data

Johane Derite
05-29-2020, 02:12 PM
Three U1 samples in new Anatolia, South Caucasus paper:

ALA017: U1a1d
ART015: U1a1d
IKI024:. U1b1

https://www.sciencedirect.com/science/article/pii/S0092867420305092

https://anthrogenica.com/attachment.php?attachmentid=37800&d=1590741879

Johane Derite
05-29-2020, 03:21 PM
Two U1 samples from

A Genetic History of the Near East from an aDNA Time Course Sampling Eight Points in the Past 4,000 Years:

SFI-56 Iron Age II female - U1a1a
SFI-50 Iron Age III female - U1a

https://www.cell.com/ajhg/fulltext/S0002-9297(20)30155-5

Johane Derite
05-29-2020, 03:29 PM
Three U1 samples from the "The Genomic History of the Bronze Age Southern Levant"

I10771 Megiddo_MLBA 1650-1550 BCE U1a1a3
I7184 Yehud_ 2500-2000 BCE U1a1
I6572 Baqah_MLBA 1550-1150 BCE U1a'c


https://www.cell.com/ajhg/fulltext/S0002-9297(20)30155-5

1938helerich
02-16-2021, 06:02 PM
Did U1a3 come to South Asia with Iranian farmers/hunter-gatherers? I recently found out my maternal haplogroup is U1a3. According to a website, U1a3 seems to be present in people from Kerala, people from northwest India, Assyrian Christians, and people of Sicily. I was wondering what population spread this haplogroup to South Asia.

vishankar
02-17-2021, 04:37 PM
Did U1a3 come to South Asia with Iranian farmers/hunter-gatherers? I recently found out my maternal haplogroup is U1a3. According to a website, U1a3 seems to be present in people from Kerala, people from northwest India, Assyrian Christians, and people of Sicily. I was wondering what population spread this haplogroup to South Asia.

i have been in personal communication with mr caccio cagetti , who has a U1 page....the distribution as mentioned is likely to be an ancient neolithic farmer population which fanned out of the middle east and levant to mediterranean europe and south west asia and , areas of pakistan( possibly the brahui and balochis) and south india....possibly these people formed the upper caste non brahmin strata in south india, which would explain the presence among nairs, kammas, syrian christians etc...in old rather outdated textbooks of anthropology there is mention of a paleo mediterranean race....i think these would broadly the people who would be carriers of this mitochondrial haplogroup!....

Lilou
04-28-2021, 11:22 PM
Hello I just got the result of 23andme, I am U1a1. I am trying to collect information on this branch but it is not the most detailed haplogroup! I hesitate to ask for the adnmt at ftdna. Will I know much more about my haplogroup?
And, thanks for this post.

GailT
04-30-2021, 04:14 AM
Hello I just got the result of 23andme, I am U1a1. I am trying to collect information on this branch but it is not the most detailed haplogroup! I hesitate to ask for the adnmt at ftdna. Will I know much more about my haplogroup?
And, thanks for this post.

U1a1 is estimated to be about 24,000 years old and it has many subclades. You can upload the 23andMe results to James Lick's mthap web tool to see if any extra mutations were found that identify a more specific subclade. That analysis should help determine if it is worthwhile testing the full mtDNA sequence.

chocoholic
05-11-2021, 05:24 PM
Hello I just got the result of 23andme, I am U1a1. I am trying to collect information on this branch but it is not the most detailed haplogroup! I hesitate to ask for the adnmt at ftdna. Will I know much more about my haplogroup?
And, thanks for this post.

If your maternal grandma was Algerian Jewish, your haplogroup makes sense. That haplogroup has been found in Chuetas (crypto-Jews) who live in the Balearic Islands. My Jewish great grandpa has that same haplogroup and I was told by a historian that many Jews from the Balearic Islands went to Abruzzo, Italy, which makes sense given that he was from that region!

Lilou
05-12-2021, 09:19 PM
U1a1 is estimated to be about 24,000 years old and it has many subclades. You can upload the 23andMe results to James Lick's mthap web tool to see if any extra mutations were found that identify a more specific subclade. That analysis should help determine if it is worthwhile testing the full mtDNA sequence.

The Geneanet and James Lick sites gave me the U1a1a1 branch. This haplogroup comes from my Jewish maternal grandmother in Algeria.The oldest ancestor in the matrilineal line lived in Algeria in the early 18th century.

GailT
05-13-2021, 03:37 AM
The Geneanet and James Lick sites gave me the U1a1a1 branch. This haplogroup comes from my Jewish maternal grandmother in Algeria.The oldest ancestor in the matrilineal line lived in Algeria in the early 18th century.

U1a1a1 is estimated to be about 13,000 years old and probably originated in the Middle East. Most people in this group have several extra mutations. If mthap identified any extra mutations, they can be useful to identify a more specific subclade of U1a1a1. If not, you might consider testing the full mtDNA sequence. You can see full sequence U1a1a1 samples that have been published in the research data base GenBank on Ian Logan's webpage. (http://www.ianlogan.co.uk/sequences_by_group/u1_genbank_sequences.htm)

Lilou
05-13-2021, 06:34 AM
U1a1a1 is estimated to be about 13,000 years old and probably originated in the Middle East. Most people in this group have several extra mutations. If mthap identified any extra mutations, they can be useful to identify a more specific subclade of U1a1a1. If not, you might consider testing the full mtDNA sequence. You can see full sequence U1a1a1 samples that have been published in the research data base GenBank on Ian Logan's webpage. (http://www.ianlogan.co.uk/sequences_by_group/u1_genbank_sequences.htm)

I contacted Ian Logan a few days ago and he told me that FTDNA says it has not found anyone in U1a1a1, but has found 10 people in U1a1a1a; but he said that this doesn't fit with us knowing that 'FTDNA kit number 189104' is 'U1a1a1-C14272T'.

GailT
05-13-2021, 08:13 PM
I contacted Ian Logan a few days ago and he told me that FTDNA says it has not found anyone in U1a1a1, but has found 10 people in U1a1a1a; but he said that this doesn't fit with us knowing that 'FTDNA kit number 189104' is 'U1a1a1-C14272T'.

FTDNA appears to have a bug in their software that is not correctly labeling the samples as U1a1a1, but they do have a large number of U1a1a1 samples (all mistakenly identified as U1a1a). You can see them listed on the U1 project page (https://www.familytreedna.com/public/U1mtDNA?iframe=mtresults)divided into proposed new subclades of U1a1a1.

kit number 189104 is in U1a1a1* Group C (defined by extra mutations 3882 and 16362) on the FTDNA project page.


One problem is that Phylotree defines U1a1a1 by two mutations: 573.XC and G9575A. but
insertions of one or more extra C's at marker 573 are extremely common and highly variable, so it should not be used to define a branch of the tree. Instead, U1a1a1 should be defined only by G9575A.