View Full Version : [Modern DNA] Rare genetic sequences illuminate early humans' history in Africa

11-04-2018, 08:44 PM
Some interesting excerpts:

These preliminary results suggest that more than 40,000 years ago, two of the groups — the San and the Baka Pygmy — were roughly twice the size of other ethnic groups present at the time, and that the San and Baka overlapped in central-eastern or southern Africa. Researchers presented these as-yet unpublished results at an American Society of Human Genetics (ASHG) meeting in San Diego, California, last week.

Nearly one-fifth of the genetic variation that the team uncovered has never before been reported. Statistical models of the data indicate that the Hadza and the Sandawe people of Tanzania shared an ancestor in the past 30,000 years.

The findings also suggest that there was intermingling during that period between the Hadza, the San in southern Africa and the Baka in central Africa, all of whom were traditionally hunter-gatherers. “I think we are seeing an ancient common ancestry between the major hunter-gatherer groups in Africa,” Tishkoff says.

This knowledge gap might dissipate in the coming years as more teams working on African genome projects publish their results. Gurdasani presented results from an analysis of whole genomes from 2,000 individuals from Uganda at the ASHG meeting last week. And H3Africa has sequenced more than 400 genomes from African individuals, says Charles Rotimi, a Nigerian genetic epidemiologist at the National Human Genome Research Institute in Bethesda, Maryland, who founded the initiative.

Source: Nature News (https://www.nature.com/articles/d41586-018-07164-9)
I wonder what else we'll find once we start getting african aDNA results genotyped with the updated 1240k SNP capture (https://twitter.com/amwkim/status/1043079659712405504).