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View Full Version : How to handle negative results (only found in raw files) for R1b



Rory Cain
11-15-2013, 11:54 PM
I've got 27 now. Is this the right folks? How does the analysis work? Can we get a list of SNPs per person downstream of L21?

Mike, are you happy with just positive results (with plus sign) and presumed positive (in brackets)? Several of these folks took Geno2.0 so have a whole host of negatives.

f20437 Reynolds DF21+ Z246+ DF25+ DF5+ Z248+ L627+ L626+ L625+ and also has 5185401G, 8381834G & 9129841 which lie between Z246 and CTS3655 and may or may not be parallel with any existing SNPs.
f28714 Cain (DF21) (Z246) (DF25) (DF5) (Z248) L658+ (close kin have tested positive for all markers in brackets except DF25, not tested)
fN3362 Maher DF21+
f196041 Williamson DF21+ (S424)
fN36510 Fueston DF21+

Mikewww
11-16-2013, 04:54 PM
Mike, are you happy with just positive results (with plus sign) and presumed positive (in brackets)? Several of these folks took Geno2.0 so have a whole host of negatives.

f20437 Reynolds DF21+ Z246+ DF25+ DF5+ Z248+ L627+ L626+ L625+ and also has 5185401G, 8381834G & 9129841 which lie between Z246 and CTS3655 and may or may not be parallel with any existing SNPs.
f28714 Cain (DF21) (Z246) (DF25) (DF5) (Z248) L658+ (close kin have tested positive for all markers in brackets except DF25, not tested)
fN3362 Maher DF21+
f196041 Williamson DF21+ (S424)
fN36510 Fueston DF21+

I'm not sure if my happiness is of importance to everyone here, but I am not sure what you are saying. Are you talking about the way I use parantheses and squiggly brackets in the spreadsheet? or the Revelant/Downstream SNPs column? We should probably start a different thread if we are talking about Geno 2 or Chromo 2's derived SNP format and things like how Morley's tool works.

Mikewww
11-16-2013, 05:21 PM
Having all of the newly discovered SNPs are great. Negative (ancestral) results are important too, as our positive (derived) results. With so many SNPs, it's quite a flood to things to look at when scanning across results amongst people. Just try going to an FTDNA project Y DNA SNP report screen and looking at Geno 2 results. It's quite an eye test and you have to have a good memory for the current phylogenetic tree and under investigation SNPs to make sense of it. Comparing several simultaneously is nearly impossible for a feeble mind like mine.

Of course, automated help can be found. Chris Morley's tool is very nice for that. I try to use a spreadsheet table of the phylogenetic tree and formulas to pull out the "defining" (current terminal) SNP and the immediately downstream negative results. This works decently for Y DNA SNP report types of input data. It is my understanding that Chromo 2 will provide a the derived SNP signature in a similar type of string of characters.

However, to ascertain negative results versus no calls, opening up raw results files is required today. It's exhaustive and that is the kind of thing David Reynolds has done for L21 in the past. I think that is what FG does in some of their analysis too. That's all good but we are entering the day where we need to compare massive amounts of data in different formats.