View Full Version : What is A23757 del+ event on YSEQ ?

11-28-2018, 03:33 AM
Hello, I am H-M82+ & certified HM36- on FTDNA.

When I ordered YSEQ I got following in first round allele results.

A23757 ChrY 9555333 9555337 del+
M2854 ChrY 13636950 13636950 G-
SK1225 ChrY 9555331 9555331 T+

Any one know what is this A23757 ?

11-28-2018, 10:07 AM
When YSEQ analyze a SNP marker, they really sequence a region of approximately +/- 200 bases around the SNP that you ordered. You can see that the position of A23757 at ChrY(hg38):9555337 is rather close to the SNP SK1225 at ChrY(hg38):9555331, so it got picked up when they were analyzing SK1225 (which you're positive for). YSEQ say that in most cases those markers are not very helpful for the test taker, but in rare cases they may contain valuable additional information, so they let you know in case it is useful.

The designation del+ means that you have a deletion at position ChrY(hg38):9555337. Insertions and deletions are collectively called INDELs. These are short polymorphisms that corresponds to the addition or removal of a small number of bases in a DNA sequence. INDELs are quite abundant, although not quite as abundant as SNPs. It is estimated that there are 1-2 million short INDELs segregating at low to high frequency in modern human populations.

11-28-2018, 12:13 PM
Thanks for clarifying...