View Full Version : Analysis of the human Y-chromosome haplogroup Q characterizes.. (Grugni et al., 2019)

02-02-2019, 11:50 AM
34 new academic samples from Grugni et al., 2019

NA12 Meso America Mexico https://www.yfull.com/tree/Q-Y4300/
NA34 Central America Panama https://www.yfull.com/tree/Q-M3/
NA58 Meso America Mexico https://www.yfull.com/tree/Q-CTS2731*/
NA3 Central America Panama https://www.yfull.com/tree/Q-Y12421/
NA35 Central America Panama https://www.yfull.com/tree/Q-Y12421/
NA11 South East America Brazil https://www.yfull.com/tree/Q-M3/
NA23 South East America Paraguay https://www.yfull.com/tree/Q-M3/
NA15 South America Peru https://www.yfull.com/tree/Q-CTS4000/
NA13 South America Peru https://www.yfull.com/tree/Q-CTS4000/
NA2 South America Bolivia https://www.yfull.com/tree/Q-CTS4000/
NA30 South East America Argentina https://www.yfull.com/tree/Q-Z5906*/
NA59 South America Peru https://www.yfull.com/tree/Q-Y780*/
NA1 South America Peru https://www.yfull.com/tree/Q-Y805/
NA61 South America Peru https://www.yfull.com/tree/Q-M3/
NA33 South America Peru https://www.yfull.com/tree/Q-Z5911/
NA52 Meso America Mexico https://www.yfull.com/tree/Q-CTS2730/
NA42 Meso America Mexico (Valley Zapotecs) https://www.yfull.com/tree/Q-CTS2730/
NA4 South America Peru https://www.yfull.com/tree/Q-CTS2730/
NA62 Central America Panama https://www.yfull.com/tree/Q-CTS2730/
NA5 South America Colombia https://www.yfull.com/tree/Q-CTS2730/
NA22 Meso America Mexico https://www.yfull.com/tree/Q-YP1111/
NA53 Meso America Mexico https://www.yfull.com/tree/Q-YP921/
NA25 Meso America Mexico https://www.yfull.com/tree/Q-YP921/
NA31 South America Colombia https://www.yfull.com/tree/Q-Z781*/
EA46 East Asia Mongolia/Khovd, Myangad https://www.yfull.com/tree/Q-YP1691/
EA45 East Asia Mongolia/Khovd, Myangad https://www.yfull.com/tree/Q-BZ180/
EA63 Europe Ukraine https://www.yfull.com/tree/Q-Y15684*/
EA38 Siberia Kamchatka (Koryaks) https://www.yfull.com/tree/Q-YP1500/
EA43 South East Asia China https://www.yfull.com/tree/Q-Y515/
EA49 Middle East Iran/Lorestan https://www.yfull.com/tree/Q-YP1677/
EA51 Middle East Iran/Golestan https://www.yfull.com/tree/Q-BZ306/
NA56 Central America Panama https://www.yfull.com/tree/Q-BZ386/
EA47 Europe Italy/Lombardy, Bergamo https://www.yfull.com/tree/Q-Y28557/
EA50 South Asia India (Hindu) https://www.yfull.com/tree/Q-Y34111*/


Research article
Open Access

Analysis of the human Y-chromosome haplogroup Q characterizes ancient population movements in Eurasia and the Americas

Viola Grugni†, Alessandro Raveane†, Linda Ongaro, Vincenza Battaglia, Beniamino Trombetta, Giulia Colombo, Marco Rosario Capodiferro, Anna Olivieri, Alessandro Achilli, Ugo A. Perego, Jorge Motta, Maribel Tribaldos, Scott R. Woodward, Luca Ferretti, Fulvio Cruciani, Antonio Torroni and Ornella SeminoEmail authorView ORCID ID profile

†Contributed equally
BMC Biology201917:3


© The Author(s). 2019

Received: 1 October 2018Accepted: 21 December 2018Published: 24 January 2019



Recent genome studies of modern and ancient samples have proposed that Native Americans derive from a subset of the Eurasian gene pool carried to America by an ancestral Beringian population, from which two well-differentiated components originated and subsequently mixed in different proportion during their spread in the Americas. To assess the timing, places of origin and extent of admixture between these components, we performed an analysis of the Y-chromosome haplogroup Q, which is the only Pan-American haplogroup and accounts for virtually all Native American Y chromosomes in Mesoamerica and South America.


Our analyses of 1.5 Mb of 152 Y chromosomes, 34 re-sequenced in this work, support a “coastal and inland routes scenario” for the first entrance of modern humans in North America. We show a major phase of male population growth in the Americas after 15 thousand years ago (kya), followed by a period of constant population size from 8 to 3 kya, after which a secondary sign of growth was registered. The estimated dates of the first expansion in Mesoamerica and the Isthmo-Colombian Area, mainly revealed by haplogroup Q-Z780, suggest an entrance in South America prior to 15 kya. During the global constant population size phase, local South American hints of growth were registered by different Q-M848 sub-clades. These expansion events, which started during the Holocene with the improvement of climatic conditions, can be ascribed to multiple cultural changes rather than a steady population growth and a single cohesive culture diffusion as it occurred in Europe.


We established and dated a detailed haplogroup Q phylogeny that provides new insights into the geographic distribution of its Eurasian and American branches in modern and ancient samples.

02-02-2019, 12:05 PM
I thin EA49 and EA51 are mixed up. Grugni et al 2012 only has Q-m25 among azerbaijanis and Turkmens from Golestan

03-01-2019, 08:00 PM
I thin EA49 and EA51 are mixed up. Grugni et al 2012 only has Q-m25 among azerbaijanis and Turkmens from Golestan

TRMCA 150 years, I think it is definitely a mixup, the trmca suggests its probably a Turkmen from Golestan, whereas lorestan is not known for their Turkmen population.