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View Full Version : Complete Genenome of Neanderthal from the Altai Mountains ( Prüfer 2013)



Jean M
12-18-2013, 07:49 PM
Kay Prüfer, The complete genome sequence of a Neanderthal from the Altai Mountains, Nature (Published online 18 December 2013)

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12886.html


We present a high-quality genome sequence of a Neanderthal woman from Siberia. We show that her parents were related at the level of half-siblings and that mating among close relatives was common among her recent ancestors. We also sequenced the genome of a Neanderthal from the Caucasus to low coverage. An analysis of the relationships and population history of available archaic genomes and 25 present-day human genomes shows that several gene flow events occurred among Neanderthals, Denisovans and early modern humans, possibly including gene flow into Denisovans from an unknown archaic group. Thus, interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene. In addition, the high-quality Neanderthal genome allows us to establish a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neanderthals and Denisovans.

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Comment from Dienekes http://dienekes.blogspot.co.uk/2013/12/a-neandertal-from-altai-mountains.html

Jean M
12-19-2013, 03:50 PM
Razib Khan weighs in to the discussion: http://www.unz.com/gnxp/not-separate-but-not-equal/

He gives us the same diagram that Dienekes picked out:

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A possible model of gene flow events in the late Pleistocene.

GailT
12-22-2013, 05:47 AM
John Hawks has a summary of the conclusions and an interesting discussion (link). (http://johnhawks.net/weblog/reviews/neandertals/neandertal_dna/altai-neandertal-genome-2013.html) He makes the point: "Some of the conclusions in this paper will not last long as more ancient genomes are sequenced." It is an amazing time for human origins research.