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Ebizur
06-16-2021, 12:38 PM
In Wook Hwang, Kicheol Kim, Eun Ji Choi, and Han Jun Jin, "Association of mitochondrial haplogroup F with physical performance in Korean population." Genomics & Informatics 2019; 17(1): e11. Published online: March 31, 2019. DOI: https://doi.org/10.5808/GI.2019.17.1.e11


We analyzed a total of 111 athletes (85 males and 26 females) enrolled in College of Sports Science at Dankook University (https://en.wikipedia.org/wiki/Dankook_University) in Cheonan, Korea (Table 1). The athlete group included subjects who participated in basketball, climbing, rugby, soccer, golf, baseball, ssireum, rowing, speed skating, short track, soft ball, tennis, soft tennis, marathon, running, judo, badminton, swimming, horse-riding, weight lifting, aerobics, jazz dance, body building, rhythmic gymnastics, squash, taekwondo, shooting, and futsal. The control group involved a total of randomly selected (therefore, likely to be unrelated) 145 subjects (72 males, 73 females) among students of College of Natural Science at Dankook University; none were regularly trained for athletics or had success in any official competitions.

Athletes (85 males and 26 females) enrolled in College of Sports Science at Dankook University in Cheonan, Korea
9/111 = 8.1% A
15/111 = 13.5% B4
4/111 = 3.6% B5
20/111 = 18.1% D4(xD4a, D4b)
5/111 = 4.5% D4a
1/111 = 0.9% D4b
7/111 = 6.3% D5
14/111 = 12.6% F
6/111 = 5.4% G
1/111 = 0.9% M
11/111 = 9.9% M7
5/111 = 4.5% M8
2/111 = 1.8% M9
3/111 = 2.7% M10
7/111 = 6.3% N9a
1/111 = 0.9% Y

Randomly selected students of College of Natural Science at Dankook University
17/145 = 11.7% A
16/145 = 11.0% B4
7/145 = 4.8% B5
33/145 = 22.8% D4(xD4a, D4b)
11/145 = 7.6% D4a
7/145 = 4.8% D4b
9/145 = 6.2% D5
6/145 = 4.1% F
7/145 = 4.8% G
13/145 = 9.0% M7
8/145 = 5.5% M8
1/145 = 0.7% M9
1/145 = 0.7% M10
1/145 = 0.7% M11
5/145 = 3.4% N9a
3/145 = 2.1% Y

Dankook University total
26/256 = 10.2% A

31/256 = 12.1% B4
11/256 = 4.3% B5
42/256 = 16.4% B total

53/256 = 20.7% D4(xD4a, D4b)
16/256 = 6.3% D4a
8/256 = 3.1% D4b
77/256 = 30.1% D4 total
16/256 = 6.3% D5
93/256 = 36.3% D total

20/256 = 7.8% F

13/256 = 5.1% G

1/256 = 0.4% M(xD, G, M7, M8, M9, M10, M11)
24/256 = 9.4% M7
13/256 = 5.1% M8
3/256 = 1.2% M9
4/256 = 1.6% M10
1/256 = 0.4% M11

12/256 = 4.7% N9a
4/256 = 1.6% Y

Bon San Koo, Yoonah Song, Seunghun Lee, Yoon-Kyoung Sung, Kyoung-Jin Shin, Nam H. Cho, and Jae-Bum Jun, "Analysis of Asian Mitochondrial DNA Haplogroups Associated With the Progression of Knee Osteoarthritis in Koreans." Journal of Rheumatic Diseases 2020; 27(3): 168-173. https://doi.org/10.4078/jrd.2020.27.3.168


As described in our previous study [Koo BS, Song Y, Lee S, Sung YK, Shin KJ, Cho NH, et al. "Association of Asian mitochondrial DNA haplogroup B with new development of knee osteoarthritis in Koreans." Int J Rheum Dis 2019;22:411-6.], we used the Ansung (https://en.wikipedia.org/wiki/Anseong) cohort of an ongoing, prospective cohort study that is part of the Korean Genome and Epidemiology Study.

30/309 = 9.71% A
49/309 = 15.86% B

1/309 = 0.32% D(xD4, D5)
31/309 = 10.03% D4(xD4a, D4b, D4e)
18/309 = 5.83% D4a
3/309 = 0.97% D4b(xD4b2)
20/309 = 6.47% D4b2
5/309 = 1.62% D4j
11/309 = 3.56% D4e
1/309 = 0.32% D4a/D4b
25/309 = 8.09% D5
115/309 = 37.2% D total

28/309 = 9.06% F
19/309 = 6.15% G
3/309 = 0.97% M(xD, G, M7, M8, M9, M10)
21/309 = 6.80% M7
19/309 = 6.15% M8
5/309 = 1.62% M9
2/309 = 0.65% M10
18/309 = 5.83% N9

Ebizur
07-24-2021, 11:54 AM
cf. Jungeun Kim, Sungwon Jeon, Jae-Pil Choi, et al., "The Origin and Composition of Korean Ethnicity Analyzed by Ancient and Present-Day Genome Sequences." Genome Biol Evol. 2020 May; 12(5): 553–565. Published online 2020 Mar 27. doi: 10.1093/gbe/evaa062

High-resolution mtDNA haplogroup assignments of 88 Korean samples from the KoVariome database

1/88 A
1/88 A+152+16362
2/88 A+152+16362+200
1/88 A3
1/88 A5a
1/88 A5a1
1/88 A5a1a1b
1/88 B4a1c3a
1/88 B4a1c3b
1/88 B4b1a2
1/88 B4c1b1
1/88 B4d3a1
1/88 B5a2a1b
1/88 B5b1
1/88 [email protected]
1/88 B5b3a
1/88 C4a1a
1/88 C4a1a+195
1/88 C4a2a1
1/88 C4a2b
1/88 C7
2/88 C7a1c
1/88 D4
1/88 D4a
2/88 D4a1
1/88 D4a1b
1/88 D4a2
1/88 D4b1a
1/88 D4b1a1a
1/88 D4b2b
2/88 D4b2b6
1/88 D4b2d
1/88 D4d
1/88 D4e
1/88 D4e1a2a
1/88 D4e2a
2/88 D4f1
1/88 D4g1
1/88 D4j
1/88 D4j3a
2/88 D4k
1/88 D5a2a1
3/88 D5b1a1
1/88 D5b1b
1/88 D5b1b2
1/88 D6a1
3/88 F1a1
1/88 F1b1a
1/88 F1b1a1a1
1/88 F1b1d
2/88 G1a1a
2/88 G2a1+16189
1/88 G2a1e
1/88 G2a5
2/88 G3a2a
1/88 M7a1a
2/88 M7a1a7
1/88 M7b1a1a
1/88 M7b1a1a1
2/88 M7b1a1a1b
1/88 M9a4b
1/88 M10a1b
1/88 M11a
1/88 N9a1
1/88 N9a2a
1/88 N9a2a2
1/88 N9a5
2/88 R11b
2/88 Y1
2/88 Z3

Ebizur
10-20-2021, 07:36 AM
In Wook Hwang, Kicheol Kim, Eun Ji Choi, and Han Jun Jin, "Association of mitochondrial haplogroup F with physical performance in Korean population." Genomics & Informatics 2019; 17(1): e11. Published online: March 31, 2019. DOI: https://doi.org/10.5808/GI.2019.17.1.e11

Athletes (85 males and 26 females) enrolled in College of Sports Science at Dankook University in Cheonan, Korea
9/111 = 8.1% A
15/111 = 13.5% B4
4/111 = 3.6% B5
20/111 = 18.1% D4(xD4a, D4b)
5/111 = 4.5% D4a
1/111 = 0.9% D4b
7/111 = 6.3% D5
14/111 = 12.6% F
6/111 = 5.4% G
1/111 = 0.9% M
11/111 = 9.9% M7
5/111 = 4.5% M8
2/111 = 1.8% M9
3/111 = 2.7% M10
7/111 = 6.3% N9a
1/111 = 0.9% Y

Randomly selected students of College of Natural Science at Dankook University
17/145 = 11.7% A
16/145 = 11.0% B4
7/145 = 4.8% B5
33/145 = 22.8% D4(xD4a, D4b)
11/145 = 7.6% D4a
7/145 = 4.8% D4b
9/145 = 6.2% D5
6/145 = 4.1% F
7/145 = 4.8% G
13/145 = 9.0% M7
8/145 = 5.5% M8
1/145 = 0.7% M9
1/145 = 0.7% M10
1/145 = 0.7% M11
5/145 = 3.4% N9a
3/145 = 2.1% YAccording to Wikipedia (https://en.wikipedia.org/wiki/Dankook_University), Dankook University's College of Natural Science is located on their Jukjeon Campus in Yongin, Gyeonggi Province, South Korea. Therefore, these two samples from Dankook University probably have been collected at two different sampling locations. However, the municipalities in which the two campuses of Dankook University are located (Cheonan, South Chungcheong Province and Yongin, Gyeonggi Province) are separated only by the city of Anseong (Ansung), so they are quite close to each other, and the sampled individuals likely have originated from various locations in South Korea.

The following is a new sample of Koreans collected in Seoul:

cf. Yeonmi Lee, Sun-Mi Lee, Jiwan Choi, et al., "Mitochondrial DNA Haplogroup Related to the Prevalence of Helicobacter pylori." Cells 2021, 10, 2482. https://doi.org/10.3390/cells10092482.


2. Materials and Methods
2.1. Subjects and Sample Collection
All subjects were recruited from Asan Medical Center, Seoul, Korea. Written informed
consent was obtained from each subject. Two mucosal biopsy specimens from 43 subjects,
45–78-year-old of Korean people, were obtained from the gastric antrum and corpus greater
curvature using standard-sized biopsy forceps during endoscopy. The H. pylori test was
performed on both the antrum and body because the H. pylori positivity rate in the antrum
and body may be different depending on the patient’s gastric acid secretion level. The
positive or negative of H. pylori in mucosal biopsy specimens were confirmed by culturing
on Brucella broth agar. This study was approved by the Institutional Review Board for
Human Research at Asan Medical Center (IRB number: 2020-0108).1/43 A
1/43 B4a
1/43 B4b
2/43 B4c
2/43 B5a
3/43 B5b
1/43 C
2/43 D4a
2/43 D4b
1/43 D4f
1/43 D4g
1/43 D4h
2/43 D4i
2/43 D4j
1/43 D5a
2/43 F1a
1/43 F1b
1/43 G1a
1/43 G2a
2/43 G3a
4/43 M7b
2/43 M7c
1/43 M8a
1/43 M9a
2/43 M10a
3/43 N9a

47117

Ebizur
07-03-2022, 03:31 AM
cf. In Wook Hwang, Bit Na Kwon, Hyung Jun Kim, Seung Hun Han, Noo Ri Lee, Myung Ho Lim, Ho Jang Kwon, and Han Jun Jin, "Assessment of associations between mitochondrial DNA haplogroups and attention deficit and hyperactivity disorder in Korean children." Mitochondrion 47:174-178 (2019 Jul). doi: 10.1016/j.mito.2018.11.003. Epub 2018 Nov 10.

28/472 = 5.93% A
51/472 = 10.81% B4
18/472 = 3.81% B5
41/472 = 8.69% F

27/472 = 5.72% N9a
12/472 = 2.54% Y
1/472 = 0.21% N9(xN9a, Y)
2/472 = 0.42% N*

180/472 = 38.14% N total

40/472 = 8.47% D4a
26/472 = 5.51% D4b
76/472 = 16.10% D4(xD4a, D4b)
24/472 = 5.08% D5
166/472 = 35.17% D total

40/472 = 8.47% G
42/472 = 8.90% M7
23/472 = 4.87% M8'CZ
9/472 = 1.91% M9
7/472 = 1.48% M10
2/472 = 0.42% M11
3/472 = 0.64% M*

292/472 = 61.86% M total


We analyzed a total of 472 children who were collected from the Children’s
Health and Environmental Research (CHEER) cohort study (Ha et al., 2009)
and the study of Kwon et al. (2014). Of these, 120 Children with ADHD and
322 controls were recruited from the CHEER cohort study and 30 Children with
ADHD were recruited from a subset of Kwon et al.’s study (2014). The CHEER
study was conducted from 2005 to 2010. The participants in the survey included
elementary school children from 10 cities in Korea, and they were followed up
biennially. An interview was randomly conducted with children using the
Korean version of the Dupaul Attention Deficit Hyperactivity Disorder Rating
Scales (K-ARS) (Kim et al., 2002), including 18 items based on the DSM-IV
diagnostic criteria for ADHD.


Ha, M., Kwon, H.J., Lim, M.H., Jee, Y.K., Hong, Y.C., Leem, J.H., Sakong, J.,
Bae, J.M., Hong, S.J., Roh, Y.M., Jo, S.J., 2009. Low blood levels of lead
and mercury and symptoms of attention deficit hyperactivity in children: a
report of the children's health and environment research (CHEER).
Neurotoxicology. 30, 31-6.


Kwon, H.J., Jin, H.J., Lim, M.H., 2014. Association between monoamine
oxidase gene polymorphisms and attention deficit hyperactivity disorder in
Korean children. Genet. Test. Mol. Biomarkers. 18, 505-509.

Ebizur
07-03-2022, 02:10 PM
cf. Miroslava Derenko, Boris Malyarchuk, Tomasz Grzybowski, Galina Denisova, Irina Dambueva, Maria Perkova, Choduraa Dorzhu, Faina Luzina, Hong Kyu Lee, Tomas Vanecek, Richard Villems, and Ilia Zakharov, "Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations." Am. J. Hum. Genet. 2007; 81:1025–1041. DOI: 10.1086/522933

Koreans from South Korea
3/103 = 2.9% A4
4/103 = 3.9% A5
13/103 = 12.6% B4
8/103 = 7.8% B5
1/103 = 1.0% C(xC1, C4, C5)
33/103 = 32.0% D4
8/103 = 7.8% D5
5/103 = 4.9% F1
2/103 = 1.9% G1
3/103 = 2.9% G2a
2/103 = 1.9% G3
10/103 = 9.7% M7
5/103 = 4.9% M8a2
2/103 = 1.9% M9a
1/103 = 1.0% Y
3/103 = 2.9% N9a

Ebizur
07-07-2022, 12:29 PM
cf. Wook Kim, Tag-Keun Yoo, Dong-Jik Shin, Hyun-Wook Rho, Han-Jun Jin, Eun-Tak Kim, and Yoon-Sun Bae (2008), "Mitochondrial DNA Haplogroup Analysis Reveals no Association between the Common Genetic Lineages and Prostate Cancer in the Korean Population." PLoS ONE 3(5): e2211. doi:10.1371/journal.pone.0002211


Patients and controls
We analyzed a total of 139 Korean prostate cancer patients, who were recruited for the study from the urology department of the Eulji University School of Medicine in Seoul and Daejeon, Korea. The DNA samples included subsets of the samples examined by Kim et al. [16]. Histological classification of prostate cancer was determined according to the World Health Organization (WHO) recommendations and the Gleason pattern (Table 1). Prostate cancer tissue specimens from all of the patients were collected from frozen samples. In addition, a total of 122 Korean men who had been diagnosed as free of prostate cancer by the Eulji University hospital in Seoul and Daejeon, Korea were recruited as normal controls. These subjects were selected at random (and therefore likely to be unrelated) from the same geographical area as the cases. This study was approved by the Ethics Committee and institutional review boards of Eulji Medical Center of the Eulji University School of Medicine in Seoul, and separate written informed consent was obtained for screening and for enrollment from all participants.

7/261 = 2.7% D-5178A(xD4-3010A, D5-10397A)
18/261 = 6.9% D4a-14979C
20/261 = 7.7% D4b-8020A
36/261 = 13.8% D4-3010A(xD4a-14979C, D4b-8020A)
14/261 = 5.4% D5 (-10394DdeI/-10397AluI)
11/261 = 4.2% G-4833G(xG2a-7600A)
5/261 = 1.9% G2a-7600A
8/261 = 3.1% M7-6455T(xM7a-4386C, M7b1a1-12811C)
2/261 = 0.8% M7a-4386C
5/261 = 1.9% M7b1a1-12811C
2/261 = 0.8% C-13263G
4/261 = 1.5% M8-15487T(xC-13263G, M8a-8684T)
22/261 = 8.4% M8a-8684T
6/261 = 2.3% M*
2/261 = 0.8% N*
13/261 = 5.0% N9-5417A(xY-14178C)
1/261 = 0.4% Y-14178C
20/261 = 7.7% A-1736G
32/261 = 12.3% B-9bpd(xB5-10398G)
15/261 = 5.7% B5-10398G
6/261 = 2.3% R9-3970T(xF1-12410G)
12/261 = 4.6% F1-12410G (-12406HpaI/HincII)