View Full Version : Genetic Admixture in the Culturally Unique Peranakan Chinese Population in Southeast

08-23-2021, 05:16 AM
Genetic Admixture in the Culturally Unique Peranakan Chinese Population in Southeast Asia

Degang Wu, Peter Yiqing Li, Bangfen Pan, Zenia Tiang, Jinzhuang Dou, Ivanna Williantarra, Amadeus Yeremia Pribowo, Rizky Nurdiansyah, The SG Peranakan Project Roger S Y Foo, Chaolong Wang Author Notes

Molecular Biology and Evolution, msab187, https://doi.org/10.1093/molbev/msab187

Published: 21 June 2021

The Peranakan Chinese are culturally unique descendants of immigrants from China who settled in the Malay Archipelago ∼300500 years ago. Today, among large communities in Southeast Asia, the Peranakans have preserved Chinese traditions with strong influence from the local indigenous Malays. Yet, whether or to what extent genetic admixture co-occurred with the cultural mixture has been a topic of ongoing debate. We performed whole-genome sequencing (WGS) on 177 Singapore (SG) Peranakans and analyzed the data jointly with WGS data of Asian and European populations. We estimated that Peranakan Chinese inherited ∼5.62% (95% confidence interval [CI]: 4.766.49%) Malay ancestry, much higher than that in SG Chinese (1.08%, 0.651.51%), southern Chinese (0.86%, 0.501.23%), and northern Chinese (0.25%, 0.180.32%). A sex-biased admixture history, in which the Malay ancestry was contributed primarily by females, was supported by X chromosomal variants, and mitochondrial (MT) and Y haplogroups. Finally, we identified an ancient admixture event shared by Peranakan Chinese and SG Chinese ∼1,612 (95% CI: 1,3451,923) years ago, coinciding with the settlement history of Han Chinese in southern China, apart from the recent admixture event with Malays unique to Peranakan Chinese ∼190 (159213) years ago. These findings greatly advance our understanding of the dispersal history of Chinese and their interaction with indigenous populations in Southeast Asia.

sex-biased admixture history, Chinese, Malays, whole-genome sequencing, mitochondrial haplogroups, Y haplogroups

10-09-2021, 09:24 PM
Already posted this in the Southeast Asia subforum (https://anthrogenica.com/showthread.php?24153-Genetic-admixture-in-the-culturally-unique-Peranakan-Chinese-population-in-ISEA), but it never hurts to have duplicate threads!