View Full Version : A Southeast Asian origin for present‐day non‐African human Y chromosomes

09-01-2021, 06:48 PM

The genomes of present-day humans outside Africa originated almost entirely from a single out-migration~50,000 70,000 years ago, followed by mixture with Neanderthals contributing ~ 2% to all non-Africans. However, the details of this initial migration remain poorly understood because no ancient DNA analyses are available from this key time period, and interpretation of present-day autosomal data is complicated due to subsequent population movements/reshaping. One locus, however, does retain male-specific information from this early period: the Y chromosome, where a detailed calibrated phylogeny has been constructed. Three present-day Y lineages were carried by the initial migration: the rare haplogroup D, the moderately rare C, and the very common FT lineage which now dominates most non-African populations. Here, we show that phylogenetic analyses of haplogroup C, D and FT sequences, including very rare deep-rooting lineages, together with phylogeographic analyses of ancient and present-day non-African Y chromosomes, all point to East/Southeast Asia as the origin 50,00055,000 years ago of all known surviving non-African male lineages (apart from recent migrants). This observation contrasts with the expectation of a West Eurasian origin predicted by a simple model of expansion from a source near Africa, and can be interpreted as resulting from extensive genetic drift in the initial population or replacement of early western Y lineages from the east, thus informing and constraining models of the initial expansion.

09-01-2021, 07:05 PM
Welcome to Anthrogenica, Ylang-Ylang! Thanks, that is an interesting link.

09-01-2021, 07:13 PM
According to serial founder model, the earliest-branching non-African lineages are expected to expand and be present closer to Africa (a), but instead have expanded in East or Southeast Asia (b). Simplified Y tree is shown as reference for colours

09-01-2021, 07:56 PM