PDA

View Full Version : Haplogroup H



bradly88
07-23-2014, 06:39 PM
I took the Family Tree DNA test and came out H on my mtPlus test. So far most of my matches turned out to be H1-C16239T.

geebee
07-31-2014, 06:57 AM
I can only find two places in the R0 subtree (see http://www.phylotree.org/tree/subtree_R0.htm) where C16239T appears.

One is as the defining SNP of an unnamed sub-branch that includes H1bf, H1bg, and H1bh. The other is as one of three defining SNPs of H17c. But if you don't have A73G! -- a back mutation of one of the defining SNPs of R0, G73A -- you're not in H17c.

Chances are, you're in H1. But the trouble is -- if I recall correctly -- mtPlus only includes HVR1 and HVR2. So the defining SNP for H1, G3010A, won't be included in your results. Now if you or any of your matches has C16242T, you might be in H1bf1.

Unfortunately, H1bf, H1bg, and H1bh -- which all have C16239T -- are also defined by SNPs in the coding region.

Although normally my matches only show people who match in all three regions (including coding), I can change the filter to show just HVR1 and HVR2 matches. This increases my number of matches from three to sixty-nine.

All but two of the HVR1, HVR2 matches simply show "H". However, none of these "H" matches took the FMS test (full mitochondrial sequence). It's quite likely that most would be in at least H1 if they had.

Basically, if you really want to know your actual mtDNA haplogroup, you're going to have to take the FMS.

bradly88
08-09-2014, 12:50 AM
Here is my HVR1 and HVR2 results

HVR1 REFERENCE SEQUENCE
Show All Positions
Position CRS Your Result
C16239T, T16519C

HVR2 REFERENCE SEQUENCE
Show All Positions
Position CRS Your Result
A263G, 315.1 C

This could be my haplogroup:

Haplogroup H1bh: (A263G)(315.1C) A750G A1438G G3010A A4769G A8860G G11377A A15326G T16093C (C16239T)(T16519C)

geebee
08-09-2014, 02:52 AM
To begin with, I see that you're using CRS. Nothing wrong with that, it just means that all SNPs are given with reference to CRS, or "Cambridge Reference Sequence". (The testing company is surely actually using rCRS, which corrected some errors in the original published sequence.) The CRS, as it turns out, belongs to haplogroup H2a2a.

Anyway, for phylogenic purposes, only one of the positions you mentioned is important: C16239T. More on that in a moment.

Now since you've already said you're in H, I'm assuming that's what the company that did your testing has told you. Most likely, this means that even if they've only given you HVR1 and HVR2 results, they did test for G2706A and T7028C, which are the defining SNPs for H. But even if they hadn't, not having 73G means you do have G73A, which is the defining SNP for R0, and within R0 (at least) C16239T signals a branch of H.

But which branch? It can't be H17c, because this has the defining SNP A73G! ("!" means a back mutation to the previous version). The other possibility is a branch without a name, which is therefore sometimes referred to simply as H-C16239T.

This branch includes H1bf, H1bg (which I'm in), and H1bh. Unfortunately, the defining SNPs for each of these are not in HVR1 or HVR2, but the coding region. There is a branch of H1bf -- H1bf1 -- that is defined by C16242T, but obviously you don't have that.

So there's a good chance you are in H1bf, H1bg, or H1bh -- though you could presumably just be in H-C16239T*. Unfortunately, the only way to find out would be to take the FMS, or full mitochondrial sequence test.

bradly88
08-09-2014, 04:04 AM
This is from my RSRS:

Your Results

RSRS Values rCRS Values mtDNA Community
HVR1 DIFFERENCES FROM RSRS
A16129G T16187C C16189T T16223C G16230A C16239T T16278C C16311T
HVR2 DIFFERENCES FROM RSRS
G73A C146T C152T C195T A247G 315.1C 522.1A 522.2C

geebee
08-09-2014, 06:04 AM
Looks sort of familiar, doesn't it:

HVR1 DIFFERENCES FROM RSRS
A16129G T16187C C16189T T16223C G16230A C16239T T16278C C16311T
HVR2 DIFFERENCES FROM RSRS
G73A C146T C152T C195T A247G 315.1C 522.1A 522.2C

Those are my HVR1 and HVR2 results. May I ask what company you tested with? If FTDNA, you're probably one of my matches -- well, when I use the HVR1, HVR2 filter, anyway. My "most distant (known) matrilineal ancestor" was Marie Catherine Anne Berda dit Picard. She was born near Biloxi (Mississippi) around 1726-30.

geebee
08-09-2014, 06:18 AM
Obviously I haven't been paying close enough attention to the earlier posts in the thread -- not even my own post of just a couple of weeks ago. (Maybe old age creeping up. Or galloping up.) I can see that you've already said you took the test at Family Tree DNA. :doh:

I can't find a "Bradly" among my matches, but I presume you may be listed under a different name. Otherwise I can't think of why you wouldn't be one of my 67 HVR1, HVR2 matches. I do have a match listed only as "male relative".

Anyway, I'd still suggest upgrading from mtPlus to FMS.

bradly88
08-09-2014, 12:46 PM
You could be a match for me, Geebee. And my extended haplogroup could be H1bg. I tested with Family Tree DNA.

bradly88
09-18-2014, 04:13 PM
Hey GeeBee, guess what? I'm taking the FMS test later on in Feb. of 2015.