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bored
09-23-2014, 11:41 PM
Hi everyone. I just got my 23andme initial results and apparently my mtDNA is U4b1a1. I couldn't find too much information on it. On 23andme, this is what it shows regarding its distribution. I didn't see any other thread on this particular haplogroup. Would be great if anyone else has some insights. Thank You!
Background:I'm from Jammu, which is located in Northwest India.

http://i1283.photobucket.com/albums/a547/koshrozin/ScreenShot2014-09-23at53818PM_zps6a3b1745.png

jesus
09-24-2014, 12:28 AM
From Wiki:
[edit]
Haplogroup U4 has its origin in the Upper Palaeolithic, dating to approximately 25,000 years ago and has been implicated in the expansion of modern humans into Europe occurring before the Last Glacial Maximum.[31] U4 is an ancient mitochondrial haplogroup[32] and is relatively rare in modern populations.[33] U4 is found in Europe with highest concentrations in Scandinavia and the Baltic states[34] and is also associated with the remnants of ancient European hunting-gatherers preserved in the indigenous populations of Siberia.[35][36][37] U4 is found in Nganasans the indigenous inhabitants of the Taimyr Peninsula,[13][38] in the Mansi (16.3%) an endangered people,[37] and in the Ket people (28.9%) of the Yenisey River.[37] U4 is also preserved in the Kalash people a unique tribe among the Indo-Aryan peoples of Pakistan (current population size 3,700)[39] where it attains its highest frequency of 34%.[40][41][42]

Your subclade is most likely related to Kalash people. Upload your raw data to Gedmatch asap.

jesus
09-24-2014, 01:08 AM
U4b1a1: found in Norway, Iceland and Central Asia (Kyrgyzstan, Tajikistan)

http://www.eupedia.com/europe/Haplogroup_U4_mtDNA.shtml

ADW_1981
09-24-2014, 02:51 AM
Hi everyone. I just got my 23andme initial results and apparently my mtDNA is U4b1a1. I couldn't find too much information on it. On 23andme, this is what it shows regarding its distribution. I didn't see any other thread on this particular haplogroup. Would be great if anyone else has some insights. Thank You!
Background:I'm from Jammu, Jammu and Kashmir, which is located in Northwest India.

http://i1283.photobucket.com/albums/a547/koshrozin/ScreenShot2014-09-23at53818PM_zps6a3b1745.png

This may sound silly but I think U4b1a may have arrived in Europe with Indo-Europeans. There are actually a handful of U4b1a people from India I have seen post on the Facebook page. My specific branch is concentrated in NW Europe. Unlike older, more undifferentiated branches of U4 found in Europe probably since the foraging days.

evon
09-24-2014, 08:40 AM
Also found in Italy:
http://www.ianlogan.co.uk/sequences_by_group/u4b1a_genbank_sequences.htm

BMG
09-24-2014, 05:37 PM
From Wiki:
[edit]
Your subclade is most likely related to Kalash people. Upload your raw data to Gedmatch asap.
Kalash U4 is mostly U4a1a which is also the more common U4 subclade among south asians .

bored
09-24-2014, 06:21 PM
Kalash U4 is mostly U4a1a which is also the more common U4 subclade among south asians .

Right. I don't think my maternal haplogroup is common at all in India.

BMG
09-24-2014, 06:36 PM
Right. I don't think my maternal haplogroup is common at all in India.
It is more common in central asia .There are few U4b's in pakistani HDGP samples
HDGP0102-U4b1a1-Hazaara
HDGP0351-U4b1a4-Burusho
HDGP0290-U4b2-Kalash

HDGP0102 mutations wrt CRS . You can compare it with your result.

A73G T195C A263G G499A A750G A1438G A1811G T2083C A2706G C3107N
A3672G T4646C A4769G T5999C A6047G C7028T T7705C A8642G A8860G T9861C
C11332T T11339C A11467G G11719A T12297C A12308G G12372A C14620T C14766T A15326G
T15693C C15789T T16298C T16356C T16362C T16519C

bored
09-27-2014, 04:39 AM
It is more common in central asia .There are few U4b's in pakistani HDGP samples
HDGP0102-U4b1a1-Hazaara
HDGP0351-U4b1a4-Burusho
HDGP0290-U4b2-Kalash

HDGP0102 mutations wrt CRS . You can compare it with your result.

A73G T195C A263G G499A A750G A1438G A1811G T2083C A2706G C3107N
A3672G T4646C A4769G T5999C A6047G C7028T T7705C A8642G A8860G T9861C
C11332T T11339C A11467G G11719A T12297C A12308G G12372A C14620T C14766T A15326G
T15693C C15789T T16298C T16356C T16362C T16519C

Can you explain how I can compare this?
Btw so far I don't see any U4b1a1 South Asians. There is a Kashmiri Pandit with U4b1 and an Afridi Pashtun with U4b but most of them seem to be Euro.

BMG
09-29-2014, 02:26 PM
Can you explain how I can compare this?
Btw so far I don't see any U4b1a1 South Asians. There is a Kashmiri Pandit with U4b1 and an Afridi Pashtun with U4b but most of them seem to be Euro.

Sorry for late response .Go to the following url to access jameslick's tool
http://dna.jameslick.com/mthap/
Upload your 23&me rawdata file and you will get predicted haplogroup along with mutation list .Since 23&me doesnt cover whole mtdna you wont be getting a full list of mutation but still can be used for comparison purpose .

ADW_1981
09-29-2014, 04:22 PM
Can you explain how I can compare this?
Btw so far I don't see any U4b1a1 South Asians. There is a Kashmiri Pandit with U4b1 and an Afridi Pashtun with U4b but most of them seem to be Euro.

I'm sharing with a U4b South Asian at 23andMe. She might post here, I'm not sure.

bored
12-03-2014, 03:34 AM
So I tried James Lick's mthap tool online at http://dna.jameslick.com/mthap/

My top match is U4b1a1a1. On familytreedna website, I found that the project U4 members belonging to U4b1a1a1 subgroup trace their most distantly known direct maternal ancestor to Russia, Italy, France, Germany(2), Czech Republic and the United States.

https://www.familytreedna.com/public/U4mtDNA/default.aspx?section=mtmap

Does anyone have info on its presence in any other areas?

bored
12-03-2014, 03:50 AM
Here is the distribution of U4b according to a Russian website.

http://gentis.ru/img/mt/U4b-s.gif

Distribution of U4 overall

http://gentis.ru/img/mt/U4.gif

bored
12-03-2014, 04:15 AM
According to another Russian website (thanks jesus):


This (U4) haplogroup is separated from the great and ancient mitochondrial haplogroup U. mitochondrial haplogroup called revealed by the analysis of mitochondrial DNA sequences. Letter U is an abbreviation of the name of Ursula (Ursula), which researchers gave the ancient bearer of this haplogroup, from which all its current owners.

Haplogroup U4 was named by scientists Ulrich (Ulrike). It is separated from the maternal haplogroup U about 18 - 20 thousand years ago. Since that time, the owners of haplogroup U4 have been actively colonize the territory of Eurasia. This fact is puzzling scientists, as 20 thousand years ago the world was the ice age, and living conditions in the northern regions were very heavy.

The researchers suggest that carriers U4 waited cold in several areas in the North of Ukraine and southern Russia. This assumption is further supported by the fact that the spread of haplogroup U4 from the Germanic peoples had already begun after the glacier retreated. That is, its media has moved north after it gets warmer.

Currently haplogroup U4 most often found in Eastern Europe, Slavic and Finno-Ugric peoples. Among the Russian prevalence of this haplogroup is 5 percent. Very rarely (in 1-2 percent) U4 common in people of South Siberia and Central Asia (Kyrgyzstan, Uzbeks, Tajiks, Uighurs, Altai, Tuva, Khakassia, Shor, Yakut, Buryat). In Northern Europe in the holder haplogroup Ulrich can accurately recognize the offspring of the Germanic tribes. Therefore, most of this haplogroup is found among the Germans, Norwegians, Swedes and Icelanders. In this case, the European owners of U4 often bear its specific kind - U1b. She almost never occurs in the eastern Slavs and Finno-Finns.

The most unusual with respect to haplogroup Ulrich is that it is most common in the West Siberian Ugrian speaking peoples - Khanty and Mansi. They incidence U4 can be up to 20 percent.


U4 distribution

https://www.i-gene.ru/images/gaplogroups/U4_MT.jpg

GailT
12-03-2014, 05:54 PM
Some branches of U4 arrived in Europe during the Mesolithic, and it's likely that continuing migrations brought more U4 from the Steppe and eastern Europe to western Europe during the Neolithic and metal ages. Debbie is the volunteer adminsitrator for the U4 project and she might have a more specific answer for your sucblade.

There were some interesting Portuguese U4 samples in a recent paper, I'll follow up on those later.

ADW_1981
12-03-2014, 05:59 PM
Here is the distribution of U4b according to a Russian website.

http://gentis.ru/img/mt/U4b-s.gif



There's a very healthy cluster of U4b, in particular downstream branches in NW Europe, and to a lesser extent Scandinavia, so it's pretty clear that the map is a little biased here.

bored
12-03-2014, 08:45 PM
There's a very healthy cluster of U4b, in particular downstream branches in NW Europe, and to a lesser extent Scandinavia, so it's pretty clear that the map is a little biased here.

How do you think it got to South Asia?

Artmar
12-03-2014, 10:04 PM
U4a1b1 here, maternal origins from Netherlands

kenji.aryan
03-01-2015, 03:57 AM
U4b1a1a1: found in the northeast Caucasus, Iran (Persians), central Europe, France and Italy

Ebizur
08-26-2015, 10:00 PM
It is more common in central asia .There are few U4b's in pakistani HDGP samples
HDGP0102-U4b1a1-Hazaara
HDGP0351-U4b1a4-Burusho
HDGP0290-U4b2-KalashAccording to Lippold et al. 2014, HGDP00102 is a Hazara male who belongs to mtDNA haplogroup U4b1a1a and Y-DNA haplogroup R1b-M73, HGDP00351 is a Burusho male who belongs to mtDNA haplogroup U4b2 and Y-DNA haplogroup G2b, and HGDP00290 is a Kalash male who belongs to mtDNA haplogroup U4b1a4 and Y-DNA haplogroup G2a. I thought I should point out this discrepancy; it appears that someone has switched the mtDNA haplogroup assignment of the Kalash individual with that of the Burusho individual. Supplementary Figure 14 of Lippold et al. 2014 also shows the Burusho individual's mtDNA as belonging to an outgroup vis--vis the Kalash individual's mtDNA and the Hazara individual's mtDNA, so I suspect that the assignment of the Burusho individual's mtDNA to U4b2 is the correct one.

Anyway, among these three individuals from the HGDP, bored's mtDNA is most closely related to that of the Hazara. The TMRCA of U4b1a1 (Hazara 0102 and bored) and U4b1a4 (Kalash 0290) is approximately 11,000 to 12,000 years, and the TMRCA of U4b1 (Hazara 0102, bored, and Kalash 0290) and U4b2 (Burusho 0351) is approximately 17,000 years.

Varun R
08-26-2015, 10:14 PM
I have two anonymous DNA Relatives in 23andMe with mtDNA 'U4b' designations. Both are likely Tamil brahmins. Cousin 1's predicted haplogroup= U4b1, y-DNA= H1a. Cousin 2's predicted haplogroup = U4b1a1, y-DNA= R2