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John Doe
10-16-2014, 04:03 PM
Hello,
I tested with 23andme and they said I'm E1b1b1 M35.1, this subclade is very general, and I'd like to know if I belong to a more specific subclade (like E-V13 or E-M34), which study should I take? FTDNA's 37 markers? Or perhaps Geno 2.0?

ArmandoR1b
10-16-2014, 04:21 PM
23andme tested you for V13, V12, and M34 and since 23andme doesn't show any of those as your terminal SNP you are negative for those. To see what 23andme has tested you for follow the procedure at http://blog.kittycooper.com/2014/04/a-web-site-with-tools-for-y-and-other-dna-analysis/

For SNP testing don't get the Geno 2.0 test. Get the BigY or FullGenomes test or wait for the 50-60 panel tests that FTDNA will be releasing.

If you are willing to spend the money you could always get a 37, or preferably a 67 marker, STR marker test, apart from the SNP tests, with FTDNA to see if you have any matches at that level.

John Doe
10-16-2014, 05:02 PM
23andme tested you for V13, V12, and M34 and since 23andme doesn't show any of those as your terminal SNP you are negative for those. To see what 23andme has tested you for follow the procedure at http://blog.kittycooper.com/2014/04/a-web-site-with-tools-for-y-and-other-dna-analysis/

For SNP testing don't get the Geno 2.0 test. Get the BigY or FullGenomes test or wait for the 50-60 panel tests that FTDNA will be releasing.

If you are willing to spend the money you could always get a 37, or preferably a 67 marker, STR marker test, apart from the SNP tests, with FTDNA to see if you have any matches at that level.
I tested and the most bottom snps that are presented in green are M215/Page40/PF1942, what does that mean?

ArmandoR1b
10-16-2014, 06:01 PM
That's a good question because I don't see M35.1 on the Mendel test file using that same procedure. It's not negative or positive. I hadn't checked that until you mentioned it.

The RefSNP ID for M35.1 is rs375228668 per http://www.isogg.org/tree/ISOGG_YDNA_SNP_Index.html

Go to https://www.23andme.com/you/explorer/ and paste rs375228668 in the field next to SNP and click GO and see if you get a result. If you do and it is C then you are positive for M35.1 and there is a problem with Felix's tool. If you don't have a result at all then you still need to get tested for that SNP but it should be included in BigY, FullGenomes, or the FTDNA panel test.

ArmandoR1b
10-16-2014, 06:25 PM
I just downloaded the Mendel 23andme Y-DNA raw file and rs375228668 isn't showing up in it. It doesn't show in my 23andme file or the 23andme file of a distant relative either. I don't think that there is anything wrong with Felix's programs after all.

John Doe
10-16-2014, 06:44 PM
That's a good question because I don't see M35.1 on the Mendel test file using that same procedure. It's not negative or positive. I hadn't checked that until you mentioned it.

The RefSNP ID for M35.1 is rs375228668 per http://www.isogg.org/tree/ISOGG_YDNA_SNP_Index.html

Go to https://www.23andme.com/you/explorer/ and paste rs375228668 in the field next to SNP and click GO and see if you get a result. If you do and it is C then you are positive for M35.1 and there is a problem with Felix's tool. If you don't have a result at all then you still need to get tested for that SNP but it should be included in BigY, FullGenomes, or the FTDNA panel test.

I searched rs375228668 on 23andme and didn't find it, does that mean I should test with FTDNA and buy the 37 or 67 marker test?

ArmandoR1b
10-17-2014, 02:13 AM
I searched rs375228668 on 23andme and didn't find it, does that mean I should test with FTDNA and buy the 37 or 67 marker test?

Since rs375228668 is not in the Mendel file at I didn't think that you would have it. You can see how to enable and download the Mendel file at http://www.yourgeneticgenealogist.com/2013/12/23andme-releases-sample-of-their-new-v4.html

You need to make a choice which tests you want to get based on the following info.

The Y-DNA67 has the ability to give you matches within about the last 1,000 years. If you have a 66 marker match with another person there is a very high likelihood that you share a common paternal ancestor with that person in those 1,000 years. A majority of the time a match in that time period at that level is really less than 500 years but it isn't guaranteed. If that is something you are looking for you should get that test.

The BigY and FullGenomes tests are for 1,000-5,000 years ago. If you find a match in the BigY it is beyond the 1,000 years. It will help the genetic genealogy community find new SNPs and help you might find private SNPs. You should get the BigY if you are interested in that.

The panel tests are for currently known SNPs and won't find private SNPs. This test is for people not wanting the spend the money on the BigY. The panel tests have not been released yet.