View Full Version : Gene For Episodic Memory

01-23-2015, 01:35 AM
I have two TT alleles for rs17070145.Yippee!!!B)


People with at least one T at rs17070145 performed about 20% better than those with a C at both copies of the SNP five minutes and 24 hours after seeing or hearing the lists.


In a Swiss cohort: "Carriers of KIBRA rs17070145 T allele had 24% better free recall performance 5 min after word presentation (P = 0.000004) and 19% better free recall performance 24 hours after word presentation (P = 0.0008) than did noncarriers."

In a US cohort: "T allele carriers had significantly better memory scores than non-carriers in the Buschke's Selective Reminding Test (SRT). Performance on another episodic memory task, the Rey Auditory Verbal Learning Test (AVLT), was also significantly different between allele groups." In another Swiss cohort, with a visual episodic memory task: "T allele carriers also performed significantly better than did noncarriers in this population." "Functional magnetic resonance imaging detected KIBRA allele-dependent differences in hippocampal activations during memory retrieval."

[PMID 17353070] Replication in a healthy elderly cohor