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View Full Version : Karmin 2015 got M458 wrong



lgmayka
03-17-2015, 03:51 AM
Figure S37 of Karmin 2015 includes the following caption:
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In one case, the relationship of the branches does not follow previous work: in the Y-chromosome minimal reference phylogeny (van Oven et al. 2013), R-L260 is nested within R-M458, whereas in our dataset, the branch defined by L260 constitutes an outgroup for the group containing the branch carrying M458.
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We know, of course, that M458 is actually upstream of L260. FTDNA has no difficulty detecting M458 using either Sanger sequencing (individual SNP tests), microarrays (Geno 2.0), or next-generation sequencing (the Big Y); but apparently the authors had difficulty with it.