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GailT
10-22-2012, 09:13 AM
I looked at the HVR test results for U5 in the Behar et al paper on the Basque region. We have a lot of diversity in U5 test results for this region, including Spain, France and also the UK and Ireland, so I expected to find some interesting results in the Basque region.

The most interesting result is that U5b1f is the dominant U5 subclade in the Basque region. Using the combination of 16319A and 533G, I counted 99 U5b1f samples, or nearly 11% of the total 908 sample size. U5b1f was equally distributed among French and Basque speakers but only 3.2% among Castillian. In constrast, among nearly 1,000 U5 FMS samples available in GenBank and the FTDNA U5 project, we only have 4 FMS test results for U5b1f: DQ156208 and HQ675036 (both apparently from Spain), JX286537 from Germany and a fourth person in the U5 project with ancestry from France.

Summary of U5b1f by language
Basque 75/599 12.5%
French 20/164 12.2%
Castillian 4/124 3.2%


The remaining U5 were only 5.7% of the 908 samples, although I might have missed a few U5 with the 16270 back mutation. There are two samples I predicted to be U5b1i, another very rare subclade with only 4 known samples, from Sardinia, Germany, England and Ireland. There were also several samples for the fairly rare subclades U5a1d2a and U5b1c1a.

There were only three U5a2 samples, an unusually small percentage. I was not able to predict subclades for most of the U5a1 and U5b (excluding U5b1f) test results. There are also two samples that could be either U5a or U5b, (1370 and 1751) and it would be very interesting to test these for the full genome.

I emailed Dr. Behar about the results, and he does plan to do more FMS testing of the non-H samples, however, funding is not currently available. It might be interesting to do contributions to help support some additional testing of both U5b1f and some of the other unusual test results.

R.Rocca
07-02-2013, 02:40 PM
@GailT, I took a look at the Boattini et al. 2013 study from Italy. In Sardinia, U5b reaches 7.1%. There also seems to be some kinship between the Basques and Sardinians on a Y-DNA level with I-M26, where it reaches 39% in Sardinia, 7% in Basques, and only in trace quantities elsewhere.

GailT
07-05-2013, 05:53 AM
@GailT, I took a look at the Boattini et al. 2013 study from Italy. In Sardinia, U5b reaches 7.1%. There also seems to be some kinship between the Basques and Sardinians on a Y-DNA level with I-M26, where it reaches 39% in Sardinia, 7% in Basques, and only in trace quantities elsewhere.

The Sardinian samples have a large percentage of U5b3a1a, while the Basques are mostly a young subclade of U5b1f, so I don't think that the high percentages of U5 in both groups indicates kinship. Instead, both groups probably adopted U5 hunter-gatherers into their communities, and genetic drift in a small community might have caused a single, young subclade of U5 to become large percentage of the present day population.