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View Full Version : R-U106 negative with FTDNA, positive with 23andMe



BalkanKiwi
05-10-2015, 02:13 AM
Hi all,

So I tested R-L21 which I was predicted for before they reverted back to the default predictions. I tested negative. In the time I waited for that result I received my 23andMe results back, which gave me the haplogroup R-U106. I got a free SNP test at FTDNA so I thought I'd test R-U106 so I could be confirmed with both companies. I came back R-U106 negative.

I have no idea why or where to go to from here. Has anyone heard of this happening before?

VinceT
05-10-2015, 10:24 PM
I had tested U106- in 2006 and P312+ in 2008 with FTDNA. After extending my haplotype to 67 markers in late 2008, I was alerted to the fact that my haplotype had DYS492=13, which is usually associated with R-U106 rather than R-P312. Looking for secondary confirmation of my haplogroup assignment, I ordered a test with 23andMe in early 2009, which revealed that I was in fact P312- and U106+ once results were available in June of that year.

I had also signed up for Thomas Krahn's Walk through the Y (WTY) program in 2009, which required a fresh sample of DNA, as did a full mtDNA sequence which was also ordered from FTDNA at the end of 2008, which was also used to re-test my previous Deep-clade R results. The new mtDNA sample which was used for retesting, supported the 23andMe results.

It wasn't until September 2009 when the WTY test was completed that we were able to confirm that my original SNP results were bogus, and probably came from a completely different donor, possibly as a result of a sample mix-up at the University of Arizona, where my original sample was stored. Testing my father's DNA a year later with FTDNA also confirmed that both my STR haplotype was correct as was the more recent R-U106>L199.1 haplogroup assignment.

Without Thomas Krahn's personal involvement in the matter, I could still be assigned to a completely incorrect haplogroup. I encourage you to seek alternative testing with www.YSEQ.net (http://www.YSEQ.net), which does not rely on your existing (alleged) sample at FTDNA.

BalkanKiwi
05-16-2015, 12:27 PM
I came across this page and thought I'd give it a try, http://blog.kittycooper.com/2014/04/a-web-site-with-tools-for-y-and-other-dna-analysis/

I noticed I match all the SNPs for R1b1a2a1 L51. I haven't heard of L51 before and don't really know where it stands. Is L51 simply one above U106, P312 etc and therefore it isn't anything new?

4591

Wing Genealogist
05-16-2015, 01:09 PM
Are you absolutely certain your 23andMe result documents you are U106+? You can read a FEB 2014 blog which talks about how you can find out which SNPs you have been tested for at 23andme http://blog.kittycooper.com/2014/02/how-to-find-what-y-snps-are-tested-at-23andme/

lgmayka
05-16-2015, 07:30 PM
It wasn't until September 2009 when the WTY test was completed that we were able to confirm that my original SNP results were bogus, and probably came from a completely different donor, possibly as a result of a sample mix-up at the University of Arizona, where my original sample was stored. Testing my father's DNA a year later with FTDNA also confirmed that both my STR haplotype was correct as was the more recent R-U106>L199.1 haplogroup assignment.
Sample mixups at the University of Arizona may have been more common than we thought. Kit 231143 of Poland just received his Big Y results. They categorize him as U106+ Z381+ L48+ . But his Deep Clade at the U of A said that he was P312+ L2+ . His 37 markers, at least, are definitely correct because they are a close match to those of a relative with the same surname (kit 168318).

BalkanKiwi
05-16-2015, 11:29 PM
Are you absolutely certain your 23andMe result documents you are U106+? You can read a FEB 2014 blog which talks about how you can find out which SNPs you have been tested for at 23andme http://blog.kittycooper.com/2014/02/how-to-find-what-y-snps-are-tested-at-23andme/

Since starting this thread I've confirmed I'm U106 negative and I took that blog post one step further and I've used the MorleyDNA.com Y-SNP Terminal Subclade Predictor which suggests I'm most likely R1b-M412.

Now, looking at this R1b chart (I know its 2013 but I couldn't find a new one), http://cdn.eupedia.com/images/content/R1b-tree.gif

If I'm likely to be L51, and I'm negative for U106 and L21, does this suggest I'm a branch of P312?