PDA

View Full Version : Kuwaiti mtDNA (2012)



DMXX
12-23-2012, 05:28 PM
The Genetic Structure of the Kuwaiti Population: mtDNA Inter- and Intra-Population Variation.
Theyab JB, Al-Bustan S, Crawford MH. Hum Biol. 2012 Aug;84(4):379-403. doi: 10.3378/027.084.0403.



Abstract

This study investigated: (1) the mitochondrial DNA (mtDNA) genetic variation in 116 unrelated individuals who originated from the Arabian Peninsula, Iran, or were of Bedouin ethnicity and (2) the genetic structure of Kuwaiti populations and compared it to their neighboring populations. These subpopulations were tested for genetic homogeneity and shown to be heterogeneous. Restriction fragment length polymorphism (RFLP) and mtDNA sequencing analyses of HVRI were used to reconstruct the genetic structure of Kuwait. The results indicated that the combined Kuwaiti population has a high frequency of haplogroup R0 (17%), J (12%), and U (12%) similar to other Arabian populations. In addition, contemporary African gene flow was detected through the presence of sub-haplogroup L (L1 and L2) (2%) and the absence of L3 which is reflective of an earlier migration. Furthermore, the multidimensional scaling (MDS) plot showed that the Kuwaiti population clusters with neighboring populations, including Iran and Saudi Arabia indicating gene flow into Kuwait. According to this study, the Kuwaiti population may be undergoing an expansion in a relatively short period of time, and the maternal genetic structure of Kuwait resembles both Saudi Arabia and Iran.


Scroll down to the Appendix in this link (http://www.bioone.org/doi/abs/10.3378/027.084.0403?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed&) to view the full HVR1 haplotypes.

Humanist
12-25-2012, 09:19 PM
Thanks, DMXX. Interesting study. Though, I wonder if the authors from the study have any idea about history, and geography. I am referring to this bit from the study:


Furthermore, the multidimensional scaling (MDS) plot showed that the Kuwaiti population clusters with neighboring populations, including Iran and Saudi Arabia indicating gene flow into Kuwait. According to this study, the Kuwaiti population may be undergoing an expansion in a relatively short period of time, and the maternal genetic structure of Kuwait resembles both Saudi Arabia and Iran.


http://wwwnc.cdc.gov/travel/images/map-kuwait.png

Source: http://wwwnc.cdc.gov/travel/images/map-kuwait.png


http://destinationterre2.files.wordpress.com/2012/02/carte_elam.jpg?w=640

Source: http://destinationterre2.files.wordpress.com/2012/02/carte_elam.jpg?w=640


And, how about the Babylonians, Achaemenids, Parthians, Sassanids...?

Too bad it is behind a paywall.

DMXX
12-26-2012, 01:35 AM
I did find that comment strange also.

Unsure whether it is an intentional over-simplification (i.e. SW-Asian vs. W Asian) or subservience to a major current culturo-linguistic division in the Middle-East (Arabian vs. Iranian). That Kuwait happens to fall on the fault line between the two does not mean modern Kuwaitis are in fact a hybrid between Arabian and Iranian populations. Particularly as all manner of non-Arabic/Iranic groups existed in Mesopotamia (Sumerians, Elamites, whoever else may have facilitated the trade across the Persian Gulf and beyond).

It's a shame no apparent attempt to isolate the putative layers which eventually formed the modern Kuwaiti mtDNA profile was made. Perhaps the full article provides more information.

Ezana
12-26-2012, 07:08 AM
Just a quick note, as I haven't had time to check out the article. It's interesting to note the high (17%) frequency of R0 in Kuwait and elsewhere in the Arabian peninsula such as Yemen (IIRC, up to half) and East Africa (10-15%). On the other hand, it's quite rare in Saudi Arabia (again, if I remember correctly). Just something interesting to consider.

powervr
12-28-2012, 02:47 PM
Hello ezana, I don't want to build an off-topic here, but I want to ask you an question...

do you know if there is some male portuguese haplogroups in the indic area?
near the portuguese fortress, unlike other europeran, the portuguese did mixed with locals... portuguese stayed for more than 100 years with many people, at least near the fortress they build...

I know that ethiopia was an ally of portuguese because of religion.

there are many interesting histories with portuguese there, like defeating with only 600 man the most big army of the period with 23000 ottomans and 70 big ships... with "tomates" :D or balls....

DMXX
12-28-2012, 06:15 PM
^ I wouldn't doubt some Portuguese paternal contribution to places like Goa/Kerala. Many people from that part of India have Portuguese surnames (D'Souza) and are Christian.

Ezana
12-28-2012, 10:56 PM
Yes, I'd look up studies on Goan and Sri Lankan populations. The Portuguese Burghers, e.g., definitely carry Portuguese haplogroups and even speak a Portuguese-based creole. Off the top of my head, I don't know of any specific studies, but the data is likely out there already. It's just a matter of teasing it out.

Krefter
08-12-2015, 11:20 AM
The Genetic Structure of the Kuwaiti Population: mtDNA Inter- and Intra-Population Variation.
Theyab JB, Al-Bustan S, Crawford MH. Hum Biol. 2012 Aug;84(4):379-403. doi: 10.3378/027.084.0403.



Scroll down to the Appendix in this link (http://www.bioone.org/doi/abs/10.3378/027.084.0403?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed&) to view the full HVR1 haplotypes.

I can't find the HV1 haplotypes with that link. What is the Appendix?