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Neelvar
02-08-2016, 01:59 PM
I am a complete newbie to all this, so would appreciate if someone could illustrate the origin (ie - where was the u5a1 maternal ancestor likely born, what population did she represent) as well as how that line ended up in the Punjab region of India.

I just got my 23andme results and I am u5a1.

Punjabi Sikh as far back as I can trace.

evon
02-08-2016, 02:50 PM
From what I understand U5 is European (From the Ice age period), U5a is common in eastern Europe, so this could reflect a pre-Indo European movement of peoples from Europe into India.

You can see here:
http://www.anthrogenica.com/showthread.php?6383-Palaeolithic-aDNA-from-Europe-Posth-et-al-2016

Krefter
02-08-2016, 04:36 PM
At some-point your U5a1 probably migrated out of Europe and eventually made it to India. Your U5a1 could have been in India for 10,000 or a few hundred years, there's no way to know. Your U5a1 doesn't tell anything about recent ancestry, since it has maybe been Indian for maybe 1,000s and 1,000s of years.

Do you have HVR1, HVR2, and Coding region data of your mtDNA? Because if so I can look at it, and tell you if you have any matches among the 100s of U5a1s I have on hand. If you're really interested in finding the origins of your U5a1, you need to take a higher-coverage mtDNA test. There are certain sublineages of U5a1 which look like they expanded out of Russia in the last 5,000 years all over Eurasia.

GailT
02-08-2016, 06:29 PM
I agree with previous comments - U5a1 probably originated in southern Europe during or at the end of the last glacial maximum, and then expanded into northern and eastern Europe. Several subclades of U5a1 (U5a1a1, U5a1b, U5a1d2, U5a1g) seen to have originated in eastern European hunter-gatherers and later merged with populations from the Near East in the Steppe region, and finally spread throughout Europe and south Asia with migrations that brought Indo-European languages to these regions. You can also try using James Lick's mthap tool to see if you have any extra mutations that identify a more specific subclade of U5a1.

Neelvar
02-08-2016, 09:44 PM
Here is what I got from the James Lick tool. Does this shed additional light? I have no idea how to interpret this.

1) U5a1f1

Defining Markers for haplogroup U5a1f1:
HVR2: 73G 263G
CR: 750G 1438G 2706G 3197C 4769G 5585A 6023A 7028T 7569G 8860G 9477A 11467G 11719A 12308G 12372A 13617C 14766T 14793G 15218G 15326G
HVR1: 16192T 16256T 16270T 16311C 16399G

Marker path from rCRS to haplogroup U5a1f1a (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 14766T ⇨ R0 ⇨ 73G 11719A ⇨ R ⇨ 11467G 12308G 12372A ⇨ U ⇨ 16192T 16270T ⇨ U5 ⇨ 3197C 9477A 13617C ⇨ U5a'b ⇨ 14793G 16256T ⇨ U5a ⇨ 15218G 16399G ⇨ U5a1 ⇨ 6023A ⇨ U5a1f ⇨ 5585A 7569G 16311C ⇨ U5a1f1 ⇨ 199C 8251A ⇨ U5a1f1a ⇨ 200G 5586T 7403G

evon
02-08-2016, 10:01 PM
Here is what I got from the James Lick tool. Does this shed additional light? I have no idea how to interpret this.

1) U5a1f1

Defining Markers for haplogroup U5a1f1:
HVR2: 73G 263G
CR: 750G 1438G 2706G 3197C 4769G 5585A 6023A 7028T 7569G 8860G 9477A 11467G 11719A 12308G 12372A 13617C 14766T 14793G 15218G 15326G
HVR1: 16192T 16256T 16270T 16311C 16399G

Marker path from rCRS to haplogroup U5a1f1a (plus extra markers):
H2a2a1(rCRS) ⇨ 263G ⇨ H2a2a ⇨ 8860G 15326G ⇨ H2a2 ⇨ 750G ⇨ H2a ⇨ 4769G ⇨ H2 ⇨ 1438G ⇨ H ⇨ 2706G 7028T ⇨ HV ⇨ 14766T ⇨ R0 ⇨ 73G 11719A ⇨ R ⇨ 11467G 12308G 12372A ⇨ U ⇨ 16192T 16270T ⇨ U5 ⇨ 3197C 9477A 13617C ⇨ U5a'b ⇨ 14793G 16256T ⇨ U5a ⇨ 15218G 16399G ⇨ U5a1 ⇨ 6023A ⇨ U5a1f ⇨ 5585A 7569G 16311C ⇨ U5a1f1 ⇨ 199C 8251A ⇨ U5a1f1a ⇨ 200G 5586T 7403G

Here is some more info on U5 Sub-clades:
http://www.eupedia.com/europe/Haplogroup_U5_mtDNA.shtml#subclades

http://www.ianlogan.co.uk/sequences_by_group/u5a1f_genbank_sequences.htm

Leeroy Jenkins
02-08-2016, 11:06 PM
One of the ancient Srubnaya males was mtDNA U5a1f2 and your particular subclade, U5a1f1, is supposedly most common in Central and Northern Europeans, so my guess would be that your mtDNA is of Indo-European origins, as well.

GailT
02-09-2016, 03:14 AM
mthap predicts that you are in U5a1f1a and you also have 3 more extra mutations: 200G, 5586T, 7403G. There are three samples in U5a1f1a, a person from Poland, a Hungarian Jew and an Adygei from the Caucasus Mountains, and there are several people from northern Europe and Russia in its only subclade U5a1f1a1. One thing about your results that is a bit of a puzzle is that your extra mutation 7403 is also found in several people who are in U5a1f1 but not U5a1f1a. You can see those samples at the link above on Ian Logan's page.

C J Wyatt III
02-09-2016, 06:02 AM
I am a complete newbie to all this, so would appreciate if someone could illustrate the origin (ie - where was the u5a1 maternal ancestor likely born, what population did she represent) as well as how that line ended up in the Punjab region of India.

I just got my 23andme results and I am u5a1.

Punjabi Sikh as far back as I can trace.

Have you uploaded your atDNA from 23andMe to GEDmatch yet? I believe some autosomal DNA comparisons could shed some light on your situation.

Jack

Star93
08-01-2016, 04:05 PM
U5a1 was found in Andronovo (http://www.eupedia.com/genetics/andronovo_culture.shtml) culture as well as Bronze age Kazakhstan. Maybe there is an Indo-Iranian link.