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View Full Version : genohub: Next-Generation Sequencing Services (NGS-WGS) price comparison



ChrisR
03-24-2016, 07:49 AM
Added by Debbie to http://www.isogg.org/wiki/Next_generation_sequencing#Resources

DNA (whole genome) Sequencing and library preparation.
genohub Comparison parameters:

Number of samples to sequence
Minimum coverage per sample OR Minimum number of reads per sample

Current two cheapest prices for 10 WGS 20x (https://genohub.com/shop-by-next-gen-sequencing-project/#query=3efbb09815):


Total: $11,250.00
Academic Provider Location: Darlinghurst, Australia
Instrument: Illumina - HiSeq X
Allocation: 6 lane(s) , 10 sample(s)
Turnaround: ~48 days
Sequencing: $10,200.00
Library prep: $1,000.00
Coverage per sample: ~21.1 X
Output per sample: ~67,500 Mb
Reads per sample: ~450 M Reads
Read length: 2 x 150 (Paired End)
Library type: DNA (whole genome)
Kit: Illumina TruSeq Nano DNA
Notes: For Human WGS Applications Only

Total: $13,118.00
Non-profit Provider CLIA Certified Location: Alabama, USA
Instrument: Illumina - HiSeq X
Allocation: 6 lane(s) , 10 sample(s)
Turnaround: ~45 days
Sequencing: $10,608.00
Library prep: $2,510.00
Coverage per sample: ~21.1 X
Output per sample: ~67,500 Mb
Reads per sample: ~450 M Reads
Read length: 2 x 150 (Paired End)
Library type: DNA (whole genome)
Kit: Illumina TruSeq DNA PCR-Free
Notes: Price includes quality control check, DNA library preparation, and library quality control check.

The Illumina - HiSeq X platform has almost no competition when the cost matters: the most expensive HiSeq X offer is $30,498.00 - only HiSeq 3000/4000 and HiSeq High-Output v4 platforms have offers under this price. Other platforms go well over $100,000.
Will be interesting to see how the prices develop. And by the way: FGC has very competitive offers, since they offer additional handling and interpretation. See the price for one WGS 20x of the same two providers above:
$1,850.00 and $1,989.00

Afshar
03-24-2016, 08:12 AM
I noticed the first one is enriched DNA while the second one is PCR free, which is more desirable. The price of library prep seems too high, that can be lowered. Also I wonder if the use of the Nextseq or Miniseq for this application will produce similar results vs lower cost.