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View Full Version : New study : "The history of the Y chromosome in man." May 2016



E_M81_I3A
06-06-2016, 06:18 PM
Not sure if it was already posted about study by Poznik et al :

"The history of the Y chromosome in man"

Jennifer F Hughes & David C Page
AffiliationsCorresponding author
Nature Genetics 48, 588–589 (2016) doi:10.1038/ng.3580
Published online 27 May 2016

"Studies of the Y chromosome over the past few decades have opened a window into the history of our species, through the reconstruction and exploitation of a patrilineal (Y-genealogical) tree based on several hundred single-nucleotide variants (SNVs). A new study validates, refines and extends this tree by incorporating >65,000 Y-linked variants identified in 1,244 men representing worldwide diversity."

http://www.nature.com/ng/journal/v48/n6/full/ng.3580.html

http://pagelab.wi.mit.edu/pdf/2016-Hughes_Page.pdf

"The new study by Poznik et al. uses the unprecedented data set of whole-genome sequences generated by the 1000 Genomes Project, which includes individuals selected from 26 geographically diverse human populations. In total, the authors analyzed Y-chromosome sequences from 1,244 men... On the basis of the distribution of SNVs, the authors constructed a phylogenetic tree showing the paternal lineages connecting all of the 1,244 men studied. The structure of this new tree mirrors previous trees, which were based on 100-fold fewer SNVs. However, the wealth of information provided by the large number of both Y chromosomes and variants included in the current study further refines the tree and provides new insight into human population dynamics. For example, the expanded analysis identifies a new megagroup, which originated ~55,000 years ago and encompasses nearly all non-African males, and an ancient clade within haplogroup H, which is prominent in South Asia. At least eight major population expansions are evident in the new phylogenetic tree, and the timing of a number of these expansions correlates with notable events in human history ... The authors estimate the date for the most recent common ancestor of all Y chromosomes, which is rooted in Africa, to be ~190,000 years and the date for all non-African Y chromosomes to be ~76,000 years. "

E_M81_I3A
06-06-2016, 07:05 PM
And link to study by Poznik et al.

http://www.anthrogenica.com/showthread.php?7012-quot-Punctuated-bursts-in-human-male-demography-inferred-from-1-244-worldwide-Y-chr-quot&highlight=Poznik