View Full Version : CRISPR,a new technology that can edit DNA

rock hunter
06-23-2016, 05:07 PM
How the Science of CRISPR Can Change Your Genes , TIME’s cover story

One of the most exciting breakthroughs in science is here. CRISPR is a new technology that can edit DNA with remarkable precision, and it has the potential to change human lives forever.

With the ability to easily tweak DNA, scientists could theoretically remove genetic mutations that are responsible for incurable diseases, such as cystic fibrosis, HIV, and even certain cancers. Researchers are now beginning to test those possibilities on human cells in the lab. But CRISPR is already being used on crops, insects and more.

Watch the video below to learn more about how CRISPR works

http://timeinc.brightcove.com.edgesuite.net/rtmp_uds/293884104/201606/2675/293884104_4962654697001_4933348441001.mp4?playerId =1847503743001&lineupId=&affiliateId=&pubId=293884104&videoId=4933348441001

06-23-2016, 11:44 PM
About a year ago, a family history magazine published an article in which they discussed paternal DNA lines, using the surname Paterson/Patterson as an example.
At some stage they must have spelled something wrongly, and used global editing to cut out "pater".
But this step affected "paternal" as well, leaving a whole lot of instances of "nal", with the "pater" cut out.

Something similar was reported to have occurred in an early version of CRISPR in animal trials, with unintended areas being affected, and bits replaced that were not meant to be affected.
The video certainly does not address this.
Has anyone seen a report that adequately addresses this side-effect?
Have sufficient studies been carried out to guard against this?
And if things do go wrong, will senior management:
1) look after anyone adversely affected for the rest of their lives? And their families.
2) accept a considerable custodial sentence and/or give up body part(s) as penalty for the trouble they have caused?

Please bear in mind that any adverse consequence may not be immediately apparent, but could kick in decades later.
This is long after some statutes of limitation in some jurisdictions.