PDA

View Full Version : 75x Exome vs. 4x Genome



BrianNC
07-01-2016, 05:17 AM
I believe the high coverage exome would be more useful but I dont know for certain so I thought I would ask here.

For the purpose of finding variants related to health conditions, Would the Exome at 75X coverage be more useful then the Genome at 4X coverage?

Thanks,
Brian

Cofgene
07-01-2016, 10:50 AM
absolutely. Coverage is very important for identifying any rare variation present in your results.

BrianNC
07-02-2016, 06:51 PM
Thanks,

I think that I would need 30x coverage of the full genome to make the results reliable so the 75X Exome is a better choice because of the cost.

There are advantages that the full Genome has over the Exome but I may not have the knowledge or access to the tools to find those things anyway.

Has anyone used this company yet? The seem legitimate but new

https://www.genosresearch.com/