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Jean M
09-02-2016, 12:51 PM
Joe Pickrell tweets: https://twitter.com/joe_pickrell/status/770269194902536193


Want a look at your genome sequence? We're looking for beta testers of our genome app http://seeq.io/

On the website, it says $50, then provide a saliva sample and drop it off in any USPS mailbox. So US only.

But on Redditt https://www.reddit.com/r/science/comments/4ybtym/science_ama_series_we_are_yaniv_erlich_and_joe/

Hello Reddit! We are:

Yaniv Erlich: Professor of computer science at Columbia University and the New York Genome Center

Joe Pickrell: Professor of biology at Columbia University and the New York Genome Center

We develop new, fun ways to analyze genetic data, which we use to understand aspects of genetic privacy, infer ancient history, improve medicine, and much more.

More importantly, we want these tools to be available to everyone, including you. If you have your personal genome data, you can sign up at DNA.Land to contribute to research and learn more about your DNA. If you don't have your data, you can sign up to get sequenced by our project Seeq.

Ann Turner
10-14-2016, 11:49 PM
I signed up for this and recently received some results. The first to come in was an anlysis of my spit microbiome. Today I received an ancestry report. My known ancestry is Germain and English, so the southeast Mediterranean component must fall in the ancient category.

12152
Actually, my main motivation was to see if raw data results would be compatible with GEDmatch, and those are not yet available.

jpb
10-15-2016, 12:28 AM
I also got my Ancestry results from Seeq today. They were 54% Northwestern European, 24% Northeastern European, and 22% Southwestern European.

jpb
10-21-2016, 04:02 AM
Raw data not compatible with GEDMatch.

Ann Turner
10-22-2016, 08:38 AM
Raw data not compatible with GEDMatch.How did you get your raw data?

jpb
10-23-2016, 02:18 PM
On the app click the three white dots and click request raw data. That sends an email to your account with a link to the download.

AnnieD
10-23-2016, 07:53 PM
So this is DNA.Land "grown-up" into a commercial test that can compete with 23andMe if I understand the features offered? ;) Ancestry, Microbiomes, relative sharing - all for $50. Sounds like a bargain.

Ann Turner
10-24-2016, 11:21 AM
On the app click the three white dots and click request raw data. That sends an email to your account with a link to the download.
Thanks -- I don't see that option, but I sent a message to support.

tippy
10-24-2016, 11:31 AM
So this is DNA.Land "grown-up" into a commercial test that can compete with 23andMe if I understand the features offered? ;) Ancestry, Microbiomes, relative sharing - all for $50. Sounds like a bargain.

It's what 23andme would be charging if they weren't overpriced.

Ann Turner
10-24-2016, 11:33 AM
So this is DNA.Land "grown-up" into a commercial test that can compete with 23andMe if I understand the features offered? ;) Ancestry, Microbiomes, relative sharing - all for $50. Sounds like a bargain.
DNA.Land does relative matching in their database. Seeq.io lets you send an invitation to a specific person to view your results. I haven't actually tried that.

Ann Turner
10-24-2016, 07:33 PM
Thanks -- I don't see that option, but I sent a message to support.
I received a very prompt reply. It turns out that I needed to update the app, which did not happen automatically because I didn't have enough room on my smartphone.

The raw data is even rawer than we're used to seeing from the genealogy testing companies. It's a huge BAM file, so I need to bite the bullet and learn how to extract data from that type of file.

Ann Turner
10-27-2016, 02:40 PM
The raw data is even rawer than we're used to seeing from the genealogy testing companies. It's a huge BAM file, so I need to bite the bullet and learn how to extract data from that type of file.
For a first pass, I tried the utility kit from Felix Immanuel

http://www.y-str.org/2014/04/bam-analysis-kit.html

I'm skeptical about the output because of the very high percentage of homozygous calls. I don't know if that's a problem with the utility or low coverage in the BAM kit. I did get decent (but not perfect) results for my mtDNA, which there's only one possible allele (unless there's heteroplasmy).

If there are some BAM experts willing to take a look at this sample, you can write to me directly [email protected]

Ann Turner
10-27-2016, 02:57 PM
For a first pass, I tried the utility kit from Felix Immanuel

http://www.y-str.org/2014/04/bam-analysis-kit.html

I'm skeptical about the output because of the very high percentage of homozygous calls. I don't know if that's a problem with the utility or low coverage in the BAM kit. I did get decent (but not perfect) results for my mtDNA, which there's only one possible allele (unless there's heteroplasmy).

If there are some BAM experts willing to take a look at this sample, you can write to me directly [email protected]
I think I've answered my own question. There is very low coverage (0.10.5x).

https://medium.com/the-seeq-blog/introducing-seeq-2bc3b664f16#.io199wuf7

mtDNA probably does relatively well because there are hundreds to thousands of mtDNA molecules per cell.

Erik
10-27-2016, 07:57 PM
Just sent mine in. Anyone received their results yet? If so, please share them and also tell how long they took.