Results 1 to 9 of 9

Thread: Best company for testing

  1. #1
    Registered Users
    Posts
    27
    Sex

    Turkey Ottoman Empire Albania Ottoman Empire 2 Bosnia and Herzegovina Lazistan

    Best company for testing

    I did ancestry dna, but I did not like the test, and the results were very wrong for what we know to be our background is there any company that you would recommend is better then ancestry? Is ftdna pretty accurate.

  2. #2
    Registered Users
    Posts
    378
    Sex
    Location
    Honolulu, Hawaii
    Ethnicity
    7/8 European,1/8 Hawaiian
    Nationality
    American
    Y-DNA (P)
    R-L2>BY4242-Germany
    mtDNA (M)
    H3h-Germany
    Y-DNA (M)
    E-FT41362-Azores, Pt
    mtDNA (P)
    W6a-Slovakia

    United States of America Germany Italy Azores Slovakia Hawaii
    Is your goal is the ethnicity percentages or to find genetic cousins to assist with family reasearch?

  3. #3
    Silver Class Member
    Posts
    4,643
    Sex
    Nationality
    Canadian
    Y-DNA (P)
    R-Z198 (DF27)
    mtDNA (M)
    T2B-T152C

    England Scotland Poland Germany Canada Quebec Netherlands
    IMO ftDNA is the worst of the major companies, and 23andme is the best for autosomal ethnicity estimate.

  4. The Following 2 Users Say Thank You to sktibo For This Useful Post:

     Robert1 (10-27-2017),  [email protected] (10-27-2017)

  5. #4
    Registered Users
    Posts
    993
    Sex
    Location
    Norfolk, East Anglia, UK
    Ethnicity
    English
    Nationality
    British
    Y-DNA (P)
    L-SK1414
    mtDNA (M)
    H6a1a8

    East Anglia England European Union
    In my opinion there isn't a good autosomal DNA test for ancestry - yet! None of them are accurate below regional, or sometimes even Continental level, although some appear slightly better for identifying a few specific populations.

    Best option on autosomal is to take multiple tests, use admixture calculators, and also to look at any matches. Even then, never take the results as an indisputable truth.

  6. The Following 6 Users Say Thank You to A Norfolk L-M20 For This Useful Post:

     Amerijoe (04-26-2017),  Cascio (11-11-2017),  JMcB (04-26-2017),  Maximilian (05-22-2017),  Mixed (05-14-2017),  Robert1 (10-27-2017)

  7. #5
    Registered Users
    Posts
    742

    Quote Originally Posted by A Norfolk L-M20 View Post
    In my opinion there isn't a good autosomal DNA test for ancestry - yet! None of them are accurate below regional, or sometimes even Continental level, although some appear slightly better for identifying a few specific populations.

    Best option on autosomal is to take multiple tests, use admixture calculators, and also to look at any matches. Even then, never take the results as an indisputable truth.
    I noticed on websites that use the Joe Pickrell algorithm like DNA Land, Geneplaza, and Gencove I get high percentages of Southwestern European and North Slavic, Eastern European, and Ashkenazi. Yet on most of the commercial testing ethnicity estimates I donít.

    Then it occurred to me that there does not seem to be any reference samples from Western or Central continental Europe. The Northwestern category seems to just involve the British Isles and Scandinavia. So if you have ancestors from Western or Central Europe your ethnicity estimate is going to show larger percentages from neighboring regions to substitute a type of false equilibrium for this discrepancy.

    A lot of these companies including the commercial ones are misleading their customers about their true ancestry because they are assigning neighboring regions to make up for a lack of reference samples. Until these companies make the effort to get many more reference samples and to split up their current regions into smaller regions these ethnicity estimates are always going to be pretty incomplete and often misleading.

  8. The Following User Says Thank You to mwauthy For This Useful Post:

     A Norfolk L-M20 (10-27-2017)

  9. #6
    Registered Users
    Posts
    869
    Sex
    Location
    USA
    Nationality
    USA
    Y-DNA (P)
    I-FT248579
    mtDNA (M)
    H5

    United States of America Canada
    Quote Originally Posted by sktibo View Post
    IMO ftDNA is the worst of the major companies, and 23andme is the best for autosomal ethnicity estimate.
    Some may do admixture better than others, but if you are interested in matching to find relatives especially using GEDmatch, FTDNA Family Finder is the only one that is still producing what I consider a "standard" kit. The others are selling reduced SNP's (ones used for genealogy) kits.

    I would not go anywhere near 23andMe's new V5 chipset kits that actually makes up results (imputation).

    Jack Wyatt

  10. The Following User Says Thank You to C J Wyatt III For This Useful Post:

     Robert1 (10-27-2017)

  11. #7
    Registered Users
    Posts
    1,416
    Sex
    Location
    Glasgow, Scotland
    Ethnicity
    Pictland/Deira
    Y-DNA (P)
    R1b-M222-FGC5864
    mtDNA (M)
    H5r*

    Quote Originally Posted by C J Wyatt III View Post
    Some may do admixture better than others, but if you are interested in matching to find relatives especially using GEDmatch, FTDNA Family Finder is the only one that is still producing what I consider a "standard" kit. The others are selling reduced SNP's (ones used for genealogy) kits.

    I would not go anywhere near 23andMe's new V5 chipset kits that actually makes up results (imputation).

    Jack Wyatt
    No, the 23andMe chip contains tagSNPs that studies have proven are powerful predictors for other SNPs. The chips themselves don't impute so the calls in the raw data are all real genotyped calls.
    YSEQ:#37; YFull: YF01405 (Y Elite 2013)
    WGS (Full Genomes Nov 2015, YSEQ Feb 2019, Dante Mar 2019, FGC-10X Linked Reads Apr 2019, Dante-Nanopore May 2019, Chronomics Jan 2020, Sano Genetics Feb 2020, Nebula Genomics June 2020)
    Ancestry GCs: Scots in central Scotland & Ulster, Ireland; English in Yorkshire & Pennines
    Hidden Content
    FBIMatch: A------ (autosomal DNA) for segment matching DO NOT POST ADMIXTURE REPORTS USING MY KIT

  12. The Following User Says Thank You to MacUalraig For This Useful Post:

     sktibo (10-27-2017)

  13. #8
    Registered Users
    Posts
    869
    Sex
    Location
    USA
    Nationality
    USA
    Y-DNA (P)
    I-FT248579
    mtDNA (M)
    H5

    United States of America Canada
    Quote Originally Posted by MacUalraig View Post
    No, the 23andMe chip contains tagSNPs that studies have proven are powerful predictors for other SNPs. The chips themselves don't impute so the calls in the raw data are all real genotyped calls.
    Just a lot fewer SNP's than we are used to. OK, the imputation is being done outside of the chip.

    The trouble with imputation is the same with admixture analysis. The experts are missing something really big. It is the reason why we have so many matches, but only can see how we are related with just a handful.

    I'll take real SNP's, please, for my matching.

    Jack Wyatt

  14. The Following User Says Thank You to C J Wyatt III For This Useful Post:

     sktibo (10-27-2017)

  15. #9
    Registered Users
    Posts
    452
    Sex

    Lifestyle health and research with third party services, single test does all, may contribute to commercial research, , only recently available outside US/UK, possibly non-CLIA certifiied lab: AncestryDNA
    Validated, clear and actionable health information for extra payment, advanced ancestry analysis used in peer-reviewed publications, rough maternal/paternal haplogroups, future-proof multi-ethnicity raw data, contribute to research: 23andMe
    Compatibility with most other autosomal results with autosomal transfer, ability to match by autosomal and maternal/paternal line if tested, genealogy community projects: FTDNA
    Up-and-coming, probably best family tree database and service with subscription, autosomal transfer, most same as FTDNA without maternal/paternal options: MyHeritage
    Free with questionnaires in the USA, health and research with third party utils, genealogy matching with GedMatch genesis: Genes for Good
    Something something, this seemed UK only so I haven't really looked at it before, but now they too are accepting imports: LivingDNA
    Serious genealogy, adoptees: 23andMe Ancestry Only and AncestryDNA, autosomal transfer to FTDNA, MyHeritage, LivingDNA, GedMatch

    According to Debbie Kennett, a renowned genetic genealocist https://cruwys.blogspot.com/2017/08/...nd-revise.html the Illumina OmniExpress used by FTDNA is being phased out in favor of GSA, the new chip currently used by 23andMe and Living DNA. Be it as it may, the GSA has better coverage of multi-ethnic (Caucasian) SNP's, so it would give better matching results for multi-ethnic matches, so GSA will be favored test chip going forward. FTDNA is already handling a large amount of autosomal transfers from services with other chips, so they aren't free of the SNP confusion even now. In principle, only "matches" that represent non-genealogical background-sharing within population should be affected, but it does depend a lot on particular matching implementation.

    N.B. If it matters to you, read the fine print on the Terms of Service carefully. There's lots of misinformation on this. Most services reserve the right to use non-identifiable genetic information in whichever way they want, as well as the right to change the Terms of Service any time. The kind of research that's needed to bring new drugs on market requires strict informed consent, and genetic data without associated survey data is pretty much useless for research, or they could just analyse biological waste and save the acquisition costs.

Similar Threads

  1. Replies: 2
    Last Post: 01-20-2020, 02:47 AM
  2. Are there any DNA testing company with shipment for Iran?
    By Kargar in forum Inquiries Corner
    Replies: 4
    Last Post: 02-09-2018, 07:13 AM
  3. Replies: 3
    Last Post: 02-07-2018, 10:24 PM
  4. Behind the scenes at a DNA testing company
    By therrien.joel in forum Other
    Replies: 16
    Last Post: 12-12-2017, 02:07 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •