Results 1 to 7 of 7

Thread: rs12458349 Neanderthal Straight Hair Gene

  1. #1
    J Man
    Guest

    rs12458349 Neanderthal Straight Hair Gene

    According to my new updated 23andme results I have one copy of the ''Neanderthal'' origin allele at rs12458349 which according to them is associated with straight hair. I am TG at rs12458349. Funny thing is though I have wavy/curly hair (when I had hair lol). I can't find much information about rs12458349 and hair type though. I also see though that according to some studies it is associated with kidney disease. Anyone else have similar results at 23andme or know more about rs12458349 and Neanderthal ancestry?

  2. #2
    Registered Users
    Posts
    987
    Sex
    Location
    England
    Ethnicity
    Mixed
    Nationality
    British

    United Kingdom Netherlands Mauritius Madagascar India China
    Before I went bald on top my hair was curly and I'm TT for rs12458349
    Ethnogene: 51.4% NW European, 21.6% W European, 10.1% Southeastern African, 9.5% Southeast Asian, 4.4% South Asian, 2% Scandinavian, 1% East African
    Papertrail @ 2xggrandparents: 37.5% London, 25% Dorset, 25% Mauritius, 6.25% Netherlands, 6.25% Hampshire

  3. #3
    J Man
    Guest
    Quote Originally Posted by JFWinstone View Post
    Before I went bald on top my hair was curly and I'm TT for rs12458349
    Yes the G allele is apparently the Neanderthal version at this SNP.

  4. The Following User Says Thank You to J Man For This Useful Post:

     JFWinstone (06-09-2017)

  5. #4
    Registered Users
    Posts
    436
    Sex
    Location
    Saint-Petersburg
    Ethnicity
    Russian, German
    Nationality
    Russian
    Y-DNA (P)
    R1b-DF99
    mtDNA (M)
    U5b1e

    TT and wavy.

  6. #5
    Registered Users
    Posts
    2,098
    Sex
    Location
    Chicago, Illinois
    Ethnicity
    mixed European
    Nationality
    USA
    Y-DNA (P)
    Dad: R1b/L21/DF63
    mtDNA (M)
    K2b2
    Y-DNA (M)
    R1b-M269
    mtDNA (P)
    K2b1a1a

    United States of America England Wales Sweden Germany
    Surprised there's not another Neanderthal thread on the 23 and Me forum. This is the first test I took with the conversation piece about Neanderthal ancestry, so I was kind of looking forward to it.

    I don't have the straight hair variant (although I do have very straight hair). Nor do I have the height or less likely to sneeze after eating dark chocolate variants (I'm slightly below average in height and don't think I've ever noticed an association between dark chocolate -- which I like -- and sneezing). I do have the variant for less back hair. For the record, I do not have back hair, thank goodness!

    Anyway, I have 298 variants, which is apparently more than 82% of 23 and Me testers.

  7. The Following User Says Thank You to msmarjoribanks For This Useful Post:

     JMcB (07-15-2018)

  8. #6
    Gold Class Member
    Posts
    3,036
    Sex
    Location
    Florida, USA.
    Ethnicity
    English, Scottish & Irish
    Nationality
    American
    Y-DNA (P)
    I-FT80854
    mtDNA (M)
    H1e2
    mtDNA (P)
    K1

    England Scotland Ireland Germany Bayern Italy Two Sicilies France
    I have 277 variants which apparently is more than 52% of 23andMe customers. I’m T/T at rs12458349 and have 0 variants for straight hair, chocolate sneezing, back hair and height. I have two Neanderthal variants on 16 markers and only one on 245 marker. Other than that, I feel pretty normal. :-)

  9. The Following User Says Thank You to JMcB For This Useful Post:

     msmarjoribanks (07-16-2018)

  10. #7
    Registered Users
    Posts
    529
    Sex
    Location
    England
    Ethnicity
    English
    Nationality
    British
    Y-DNA (P)
    I1a1b1
    mtDNA (M)
    H1c3

    England Ireland Wales Scotland England North of England European Union
    I have 324 variants whilst my brother has 277.

    For rs12458349 both of us have T/T, we both have slightly curly hair. For the others mentioned in this thread -

    For the back hair variant, both of us have G/G although my brother has far more back hair than I do.

    For height, we're both A/A and G/G and roughly the same height, 5 foot 9.

    For dark chocolate (which I've actually just had some of, incidentally), we're both C/C. Neither of us sneeze after eating dark chocolate, although my brother doesn't like dark chocolate anyway.

  11. The Following User Says Thank You to Stephen1986 For This Useful Post:

     msmarjoribanks (07-16-2018)

Similar Threads

  1. Human-Neanderthal gene variance is involved in autism
    By Amerijoe in forum Medical Genetics
    Replies: 1
    Last Post: 08-04-2016, 11:44 AM
  2. Hidden red hair gene a skin cancer risk
    By rock hunter in forum Medical Genetics
    Replies: 12
    Last Post: 07-13-2016, 05:00 AM
  3. Gene associated with gray hair discovered.
    By Hanna in forum Autosomal (auDNA)
    Replies: 36
    Last Post: 03-06-2016, 03:20 PM
  4. I Discovered the Red hair Gene!!!
    By Krefter in forum Autosomal (auDNA)
    Replies: 29
    Last Post: 12-25-2015, 12:24 AM
  5. Replies: 0
    Last Post: 02-17-2013, 07:38 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •