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Thread: Warrior Gene Rs4680

  1. #1
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    Warrior Gene Rs4680

    Whats your geno type?

    rs4680(A) = Worrier or rs4680(G) = Warrior

    https://www.23andme.com/you/explorer...np_name=Rs4680

    SNP rs4680 is on chromosome 22.

    http://www.pnas.org/content/early/20....full.pdf+html


    GG MJost
    Last edited by MJost; 07-11-2013 at 03:43 AM. Reason: Title Fix *Warrior
    148326, FGC-0FW1R, YSID6 & YF3272 R-DF13>FGC5494>*7448>*5496>*5521>*5511>*5539>*5538>* 5508>*5524
     
    Watterson USA GD1/67 & GD3/111, *5508+. GD1ís fatherís sister-23andme pred. 3rd Cous w/ 0.91% DNA shared-3 seg. Largest on Chr1 w/non-Euro admix affirms my NPE paternal Watterson line via aDNA & YDNA. A 2nd pred. 4th cous has same DKA b. 1840's Georgia and MDKA d 1703 IOM. 3rd Cousin FtDNA FF is from the Watterson Ala. *5538+ b. IOM w/ GD6/67 & GD8/111 -SGD3. FGC5539+ a Scot-Ross GD13/111 -SGD8

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  3. #2
    J Man
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    AG at rs4680. So I am a worrier/warrior lol. Makes sense I guess. ...FTDNA says I do not have the Warrior gene though.

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    Pleased to report I'm a hardcore worrier with AA. Feel free to mail me a lifetime supply of stress balls.

    Worth mentioning I don't perceive myself to be a particularly "worrying" person. SNP's like this should always be accompanied with the nature (+polygenetic coding for traits) vs. nurture tagline.

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    There are a bewildering number of studies of this allele, associating it with lots of things.
    http://snpedia.com/index.php/Rs4680
    http://blog.23andme.com/news/dna-var...-our-routines/

    DNA Variation May Help Us Break Free From Our Routines

    And so begins another Friday night. When it comes to choosing where to go to dinner, my husband likes to stick with the tried and true. I like trying out new places. A new study suggests that the roots of this conflict could spring partly from our genes. It suggests that a DNA variation affecting the neurotransmitter dopamine influence a person’s willingness to explore new options instead of sticking with the status quo.

    The finding comes from a study by Michael Frank and colleagues from Brown University and the University of Arizona. The researchers focused on how people learn from positive and negative feedback. Subjects were confronted with a clock face that counted down five seconds. Before time was up they had to push a button to receive points. In some trials, the experiment was set up so that the faster they pushed the button, the more points they got. In other trials, waiting longer got more points.

    To the researchers’ surprise, people showed wide swings in response speed within each type of trial as they adjusted their timing in an attempt to maximize their scores. Computer models showed that a likely reason for these swings is that people change their strategy (pressing the button faster or slower) in proportion to how uncertain they are that a new strategy (speeding up or slowing down from what they’ve been doing) will yield better results...

    Further analysis of the data ... showed that the extent to which a person tried out new strategies correlated with variations in the COMT gene. People who carried the “Met” version of the gene were more exploratory in the face of uncertainty about what strategy to try next than people with two copies of the “Val” version.... People with two copies of the Met version were the most adventurous, but even those with only one copy were statistically different in their exploration of new strategies from the people with two copies of the Val version.

    (The different versions of the COMT gene are determined by rs4680... A=Met, G =Val)
    Last edited by Jean M; 07-11-2013 at 10:32 AM.

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    I wonder. FtDNA say something about the X chr. in their test. What did they tell you.

    MJost
    148326, FGC-0FW1R, YSID6 & YF3272 R-DF13>FGC5494>*7448>*5496>*5521>*5511>*5539>*5538>* 5508>*5524
     
    Watterson USA GD1/67 & GD3/111, *5508+. GD1ís fatherís sister-23andme pred. 3rd Cous w/ 0.91% DNA shared-3 seg. Largest on Chr1 w/non-Euro admix affirms my NPE paternal Watterson line via aDNA & YDNA. A 2nd pred. 4th cous has same DKA b. 1840's Georgia and MDKA d 1703 IOM. 3rd Cousin FtDNA FF is from the Watterson Ala. *5538+ b. IOM w/ GD6/67 & GD8/111 -SGD3. FGC5539+ a Scot-Ross GD13/111 -SGD8

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    Like my cousin J Man, I am a "woarrier" with AG.

    I guess that means we really want to club our opponents over their head, but are usually too worried they will club us back?
     

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    Other ancestral Y lines:

    E1b-M81 Ukraine (Ashkenazi)
    E1b-V13 England
    I1-M253 Ireland
    I2-M423 Ukraine
    R1a-L176.1 Scotland
    R1b-L584 Syria/Turkey (Sephardi)
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    R1b-L21 (1)England; (2)Wales?>Connecticut
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    R1b-P312 Scotland
    R1b-FGC32576 Ireland

    Other ancestral mtDNA lines:

    H1b2a Ukraine (Ashkenazi)
    H6a1a3 Ukraine
    K1a9 Belarus (Ashkenazi)
    K1c2 Ireland
    V7a Ukraine

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  11. #7
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    I am rs4680(G;G), WARRIOR!

    The funny thing is I'm a mix of warrior and worrier lol. Whats the difference between this gene and MAO-A?

  12. #8
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    Quote Originally Posted by AJL View Post
    Like my cousin J Man, I am a "woarrier" with AG.

    I guess that means we really want to club our opponents over their head, but are usually too worried they will club us back?
    Nice analogy. I sent the result of all my siblings and three of the four paternal siblings have AG too but one went to GG and my two sisters have AA. So did the one GG brother mutate from AG?

    He did say that the GG made much sense to him and explained alot about himself. I said, "Me TOO!"

    MJost
    148326, FGC-0FW1R, YSID6 & YF3272 R-DF13>FGC5494>*7448>*5496>*5521>*5511>*5539>*5538>* 5508>*5524
     
    Watterson USA GD1/67 & GD3/111, *5508+. GD1ís fatherís sister-23andme pred. 3rd Cous w/ 0.91% DNA shared-3 seg. Largest on Chr1 w/non-Euro admix affirms my NPE paternal Watterson line via aDNA & YDNA. A 2nd pred. 4th cous has same DKA b. 1840's Georgia and MDKA d 1703 IOM. 3rd Cousin FtDNA FF is from the Watterson Ala. *5538+ b. IOM w/ GD6/67 & GD8/111 -SGD3. FGC5539+ a Scot-Ross GD13/111 -SGD8

  13. #9
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    I am rs4680(G;G), too. lol

  14. #10
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    Quote Originally Posted by william0509 View Post
    I am rs4680(G;G), too. lol
    The frequency of this SNP suggests Africans and East Asians are "warriors" while Europeans and South Asians are "worriers".

    http://browser.1000genomes.org/Homo_...iation;vf=4466

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