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Thread: Results in, K1a on HVR2

  1. #1
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    Results in, K1a on HVR2

    Hi

    I received my cousin's HVR2 results this week so my paternal grandmother is a K.

    K1a and could be in any of about two dozen subclades below that. Only the full-sequence test would determine that. (from admin of K )

    Results

    HVR1 DIFFERENCES FROM RSRS

    A16129G
    T16187C
    C16189T
    T16223C
    T16224C
    G16230A
    T16278C

    HVR2 DIFFERENCES FROM RSRS

    C146T
    C152T
    A247G
    315.1C
    C497T
    522.1A
    522.2C
    522.3A
    522.4C

    HVR1 DIFFERENCES FROM rCRS

    16224C
    16311C
    16519C


    HVR2 DIFFERENCES FROM rCRS

    73G
    195C
    263G
    315.1C
    497T
    523.1C
    523.2A

  2. #2
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    Here is what Gioiello posted on a couple other forums in regards to my K results. I need to contact FTDNA to get his contribution in order to order it at the discounted rate.

    "The hg. K1a21 is carachterized by these mutations:

    HVRI: T16093C T16224C T16311C T16519C
    HVRII: A73G A153G A263G 309.1C 315.1C T408a C497T
    CR: T6407C T9428C T11017C

    But we have fron SMGF these samples from the Far East:
    HVRI: T16093C T16224C T16311C T16519C
    HVRII: A73G A153G A263G 309.1C 315.1C C497T (from Kyrgyzstan)
    and
    HVRI: T16093C T16224C T16311C T16519C
    HVRII: A73G A153G A263G 315.1C C497T (from Mongolia)
    where we may presuppose (if of course after a Coding Region exam they belonged to this haplogroup) that both T408a and 309.1C are the most recent mutation and if the mutation A153G were the most ancient of this subclade owned by the Italian Diana Panara. Also T16093C, not present in Panara, would be a mutation happened during the diffusion to East.

    We have an European sample: Mitosearch 6f4ff
    Most distant known maternal ancestor on the direct female line
    First Name: Anna
    Last Name: Rupprecht
    Year Born: 1824
    Year Died: 1905
    Country of Origin: Bavaria/Bayern, Germany
    093C,224C,311C,519C 073G,153G,263G,309.1C,315.1C,408A,497T,523.1C,523. 2A

    HQ637410 FTDNA Haplogroup [K1a] 07-DEC-2010
    A73G A153G A263G 309.1C 315.1C T408A C497T 523.1C 523.2A A750G T1189C A1438G A1811G A2706G A3480G A4769G T6407C C7028T A8860G G9055A T9428C T9698C A10398G A10550G T11017C T11299C A11467G G11719A A12308G G12372A C14167T C14766T T14798C A15326G T16093C T16224C T16311C T16519C"
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  3. #3
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    (From admin of K)

    "Your 497T mutation gets you into the major K1a subclade that is about 60% of K. 146C is found in many K subclades. 153G is less common, but is still found in more than one lower subclade of K1a. 309.1C is found in most haplogroups and subclades and is not very significant. Your other six mutations are shared by virtually every K. We now have 1,455 members who have taken the full-sequence (mtHVR2toMega or FMS) test which is necessary to officially determine your subclade. The FMS test will also find all your coding-region mutations out of 16,569 bases total (including HVR), including any which might have medical implications."


    From FTDNA Gap page results, "Anna Vona, Roma, Italia Italy Ungrouped K A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 309.1C, 315.1C "
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  4. #4
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    I don't know, I always thought my Grandmothers ancestry went back to Spain with my ggg grandparents....
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  5. #5
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    Update;

    Recent posts on eng.molgen confirm others with 153G.
    From eng.molgen

    "Hi Gioiello,
    I don't think you can call those two SMGF sequences K1a21, unless you have further information. They don't have the required 408a. Mutation 153G is found in several other subclades of K.
    and these are my replies:
    1)
    Hi Bill Hurst, I thank you for your response and you have all the situation under your eyes. It seemed to me that 153G were a mutation pretty rare and stable (see hg. X) and that it were unlikely it were happened twice in the same haplogroup. For this I have contributed to pay the FMS test for Diana Panara, who has had only HVRI and II. My hope is that she has someone of the three mutations of the Coding Region for K1a21 and demonstrates that this subclade comes from Italy. Are the other K1a with 153G tested for the Coding Region? And are you sure that they aren't linked anyway with this subclade in heteroplasmy?
    2)
    These are all the samples found on the mtDNA Project with 153G. The first is the ancestress of Diana Panara. I am seeing that there is a sample also from Italy.
    113856 Anna Vona, Roma, Italia K A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 309.1C, 315.1C
    154040 K T16093C, A16129G, T16187C, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, T408a, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    129834 Anna Maria Marino: Sicily 1890 K1a21 T16093C, A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, T408a, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    138899 Georg Christ, 1655-1712 K1a21 T16093C, A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, T408a, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    E12783 K1a21 T16093C, A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, T408a, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    N21864 Blanche Melvin b 1909 d.2001 K1a4a1 A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 315.1C
    N60447 Baud Mouthon,1807 K1a4a1a2b A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, C16245T, T16278C C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 309.1C, 315.1C
    N47821 Eva Barbara DeCarel K1a4d A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C146T, C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    67707 Lillian Garrison 1850, Salem Co. N.J. K1a4d A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C C64Y, C146T, C152T, A153G, C195T, A247G, C497T, 522.1A, 522.2C, 309.1C, 315.1C, 522.3A, 522.4C
    226646 K1c2 A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C, C16320T A153G, C195T, A247G, C498D, 522.1A, 522.2C, 309.1C, 315.1C
    125714 peche smith soux city iowa K2a2a1 A16129G, T16187C, C16189T, T16223C, T16224C, G16230A, T16278C A153G, C195T, A247G, A512c, 522.1A, 522.2C, 315.1C
    B3231 Sarah Geers b. ABT 1795 d. between 1847-66 K2b1 A16129G, T16187C, C16188T, C16189T, T16223C, T16224C, G16230A, T16278C C152T, A153G, C195T, A247G, 522.1A, 522.2C, 315.1C"
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  6. #6
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    Solothurn and Diana...interesting information. I, too, am a K1a (according to 23andMe) with my earliest known ancestress probably born in the Bad Tolz, Bavaria area in the early 1700s. I gotta do the full mito test with FTDNA so I can participate in this discussion.

  7. The Following User Says Thank You to Grossvater For This Useful Post:

     Diana (08-14-2013)

  8. #7
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    Welcome to the K-world -- my paternal grandfather was a K1a9. K/K1 seem to have originated around West Asia though some subclades of it seem to peak around the Alps.
     

    Other ancestral Y lines:

    E1b-M81 Ukraine (Ashkenazi)
    E1b-V13 England
    I1-M253 Ireland
    I2-M423 Ukraine
    R1a-L176.1 Scotland
    R1b-L584 Syria/Turkey (Sephardi)
    R1b-L20 Ireland
    R1b-L21 (1)England; (2)Wales?>Connecticut
    R1b-L48 England
    R1b-P312 Scotland
    R1b-FGC32576 Ireland

    Other ancestral mtDNA lines:

    H1b2a Ukraine (Ashkenazi)
    H6a1a3 Ukraine
    K1a9 Belarus (Ashkenazi)
    K1c2 Ireland
    V7a Ukraine

  9. The Following 3 Users Say Thank You to AJL For This Useful Post:

     Diana (08-14-2013),  dp (08-18-2014),  Grossvater (08-14-2013)

  10. #8
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    Quote Originally Posted by Grossvater View Post
    Solothurn and Diana...interesting information. I, too, am a K1a (according to 23andMe) with my earliest known ancestress probably born in the Bad Tolz, Bavaria area in the early 1700s. I gotta do the full mito test with FTDNA so I can participate in this discussion.

    Hello, Nice to meet you! Jean keeps a nice record of ancient Eurasian DNA here, http://www.buildinghistory.org/dista...cientdna.shtml

    Check out the K's from Germany once you upgrade which I too am going to do!
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  11. The Following User Says Thank You to Diana For This Useful Post:

     Grossvater (08-14-2013)

  12. #9
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    Quote Originally Posted by AJL View Post
    Welcome to the K-world -- my paternal grandfather was a K1a9. K/K1 seem to have originated around West Asia though some subclades of it seem to peak around the Alps.
    Thank you!!! :-) So thrilled to be finding my family origins!
    R1b1a2a1a1b3 U152+ Z56+ Z144/Z145/Z146+ P312+ U106- M228.2- M160- M126- L4- L21- L2- L196- L176.2- DYS492=14 Roma, Italia.

  13. #10
    J Man
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    ^A very distant relative to haplogroup U as well. Much different histories though. You are descended from ancient farming lasses of Europe while I am descended from ancient hunting and gathering lasses of Europe.

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