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Thread: U3 Frequencies From Al-Zahery et al. 2011

  1. #1
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    U3 Frequencies From Al-Zahery et al. 2011

    Posting for possible further discussion.

    Al-Zahery et al. 2011 [+ Assyrian frequency]

    In descending order of U3 frequency:

    Code:
    7.9%	Crete
    7.3%	Assyrian
    5.5%	Iraq (Marsh Arab)
    4.9%	Georgia
    4.0%	Iraq
    3.8%	Egypt
    3.5%	Bulgaria 
    3.3%	Turkey
    3.1%	Italy (North)
    2.9%	Kurds
    2.9%	Iran
    2.4%	Saudi Arabia
    2.2%	Italy (Centre)
    2.2%	Germany
    2.1%	Azerbaijan 
    2.1%	Greece
    2.1%	Italy (Sardinia)
    2.0%	Italy (South)
    1.9%	Slovenia
    1.9%	Caucasus
    1.6%	United Arab Emirates
    1.6%	Tunisia
    1.5%	Scotland
    1.4%	Turkmenistan
    1.2%	Czech Republic 
    1.1%	Morocco (Berber)
    1.0%	Austria 
    1.0%	Ireland
    0.7%	Bosnia
    0.5%	Yemen 
    0.5%	Spain
    0.3%	Hungary
    0.2%	Pakistan
    0.1%	India
    0.0%	Morocco
    0.0%	Tajikistan

    U3 aDNA from Jean Manco's site:

    Neolithic
    1. Dnieper-Donets Ukraine 5474–5225 BC

    2. LBK Germany 5000 BC ?

    Chalcolithic
    3. Israel Wadi el‐Makkukh 4490-4335 BC


    U3 appears to be significant in the "Dead Sea sample," in the below study:

    Mitochondrial DNA variation in Jordanians and their genetic relationship to other Middle East populations.

    González et al. 2008

    RESULTS: Statistical analysis revealed that, whereas the sample from Amman did not significantly differ from their Levantine neighbours, the Dead Sea sample clearly behaved as a genetic outlier in the region. Its outstanding Eurasian haplogroup U3 frequency (39%) and its south-Saharan Africa lineages (19%) are the highest in the Middle East. On the contrary, the lack ((preHV)1) or comparatively low frequency (J and T) of Neolithic lineages is also striking. Although strong drift by geographic isolation could explain the anomalous mtDNA pool of the Dead Sea sample, the fact that its mtDNA lineage composition mirrors, in geographic origin and haplogroup frequencies, its Y-chromosome pool, points to founder effect as the main cause. Ancestral M1 lineages detected in Jordan that have affinities with those recently found in Northwest but not East Africa question the African origin of the M1 haplogroup.

    CONCLUSION: Results are in agreement with an old human settlement in the Jordan region. However, in spite of the attested migratory spreads, genetically divergent populations, such as that of the Dead Sea, still exist in the area.

    Calculated the U3 frequencies from Behar et al. (2008)

    Counting the Founders: The Matrilineal Genetic Ancestry of the Jewish Diaspora

    In descending order of U3 frequency:

    Code:
    11.1%	Iraq	Jewish
    3.4%	Azerbaijan	Jewish
    3.4%	Yemen	Jewish
    2.6%	Druze	
    2.4%	Iran	Jewish
    0.9%	Palestinian	
    0.8%	Turkey	Jewish
    0.7%	Morocco	Jewish
    0.0%	Georgia	Jewish
    0.0%	Ethiopia	Jewish
    0.0%	Bnei Israel	Jewish
    0.0%	Cochin	Jewish
    0.0%	Libya	Jewish
    0.0%	Tunisia	Jewish
    0.0%	Belmonte	Jewish
    0.0%	Bulgaria	Jewish
    0.0%	Bedouin

    The information on Wikipedia, as is often the case with regard to genetics, is incomplete:

    [U3] is found at low levels throughout Europe (about 1% of the population), the Near East (about 2.5% of the population), and Central Asia (1%). U3 is present at higher levels among populations in the Caucasus (about 6%) in Svan population from Svaneti region(Georgia, Caucasus) 4,2% and among Lithuanian Romani, Polish Romani, and Spanish Romani populations (36-56%).
    Last edited by Humanist; 09-22-2013 at 04:22 AM.

  2. #2
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    Where do u think U3 originated. mtDNA is so much more complicated than Y DNA maybe because of the differences between men and women. Almost all of Europe has basically the same haplogroup percentages and it is extremely similar to the near east which really gets annoying. There are some Paleoithic European groups were they or their ancestral version arrived in Europe probably over 30,000ybp from the near east. U(U5, U2, U8, probably more), H(H1, H3, H17 or H27, maybe more), HV(later V), maybe RO and N. Since T2b and K were in 6,700-7,400bc pre pottery Neolithic Syrian samples and early Neolithic European samples from LBK Germany about 5,000bc. I think both came to Europe in Neolithic actulley all T2 which is almost all T in ancient European samples when they can get the subclade. So maybe even T1 which was popular (10.3% of total mtDNA vast majority of T) in Indo Iranian samples in asia during late bronze and iron age like Scythians which was surprising I was thinking it might be popular in northern Russia were their ancestry may have originated which I saw one study showed it was around that range in Udmurts of Volga Russia.
    Also I am not sure but J may have also came to Europe from the near east in the Neolithic. mtDNA in Europe and near east is so extremely connected all mtDNA in Europe at somepoint came there from the Near east same with most Y DNA. I wonder why there have been so many migration from the Near east into Europe throughout history do u think it has something to do with Geography.

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    Quote Originally Posted by Fire Haired View Post
    Where do u think U3 originated
    I think the problem with U3 is that it's found at such low levels everywhere, for instance in the UK there are 11 listed:

    http://www.familytreedna.com/public/...?section=mtmap

    There was some mention of us coming into Europe with the Indo-Europeans who brought farming, some sort of link to R1b?

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    Quote Originally Posted by Humanist View Post
    Posting for possible further discussion.

    Al-Zahery et al. 2011 [+ Assyrian frequency]

    In descending order of U3 frequency:

    Code:
    7.9%	Crete
    7.3%	Assyrian
    5.5%	Iraq (Marsh Arab)
    4.9%	Georgia
    4.0%	Iraq
    3.8%	Egypt
    3.5%	Bulgaria <---- MODERN BULGARIANS
    3.3%	Turkey
    3.1%	Italy (North)
    2.9%	Kurds
    2.9%	Iran
    2.4%	Saudi Arabia
    2.2%	Italy (Centre)
    2.2%	Germany
    2.1%	Azerbaijan 
    2.1%	Greece
    2.1%	Italy (Sardinia)
    2.0%	Italy (South)
    1.9%	Slovenia
    1.9%	Caucasus
    1.6%	United Arab Emirates
    1.6%	Tunisia
    1.5%	Scotland
    1.4%	Turkmenistan
    1.2%	Czech Republic 
    1.1%	Morocco (Berber)
    1.0%	Austria 
    1.0%	Ireland
    0.7%	Bosnia
    0.5%	Yemen 
    0.5%	Spain
    0.3%	Hungary
    0.2%	Pakistan
    0.1%	India
    0.0%	Morocco
    0.0%	Tajikistan

    U3 aDNA from Jean Manco's site:

    Neolithic
    1. Dnieper-Donets Ukraine 5474–5225 BC

    2. LBK Germany 5000 BC ?

    Chalcolithic
    3. Israel Wadi el‐Makkukh 4490-4335 BC


    U3 appears to be significant in the "Dead Sea sample," in the below study:

    Mitochondrial DNA variation in Jordanians and their genetic relationship to other Middle East populations.

    González et al. 2008


    Calculated the U3 frequencies from Behar et al. (2008)

    Counting the Founders: The Matrilineal Genetic Ancestry of the Jewish Diaspora

    In descending order of U3 frequency:

    Code:
    11.1%	Iraq	Jewish
    3.4%	Azerbaijan	Jewish
    3.4%	Yemen	Jewish
    2.6%	Druze	
    2.4%	Iran	Jewish
    0.9%	Palestinian	
    0.8%	Turkey	Jewish
    0.7%	Morocco	Jewish
    0.0%	Georgia	Jewish
    0.0%	Ethiopia	Jewish
    0.0%	Bnei Israel	Jewish
    0.0%	Cochin	Jewish
    0.0%	Libya	Jewish
    0.0%	Tunisia	Jewish
    0.0%	Belmonte	Jewish
    0.0%	Bulgaria	Jewish
    0.0%	Bedouin
    The information on Wikipedia, as is often the case with regard to genetics, is incomplete:
    Read about a new study from a post on Dienekes' site:

    The American Journal of Human Genetics (2013), http://dx.doi.org/10.1016/j.ajhg.2013.10.002

    Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries

    Meredith L. Carpenter et al.

    We were able to tentatively call mtDNA haplogroups for these samples (Table S1). The two Bulgarian Iron Age individuals (P192-1 and T2G5) fell into haplogroups U3b and HV(16311), respectively. Haplogroup U3 is especially common in the countries surrounding the Black Sea, including Bulgaria, and in the Near East, and HV is also found at low frequencies in Europe and peaks in the Near East.
    Last edited by Humanist; 10-26-2013 at 06:03 PM.

  5. #5
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    Resurrecting this thread.
    A few new samples of U3 from Anatolian Aceramic early Farmers (AFF):
    ZKO, 8300-7800 BCE, Boncuklu, U3 (Y-DNA: G2a2b2b)
    ZHJ, 8300-7800 BCE, Boncuklu, U3
    ZHAJ, 8269-8210 cal BCE, U3

    Feldman et al. “Late Pleistocene human genome suggests a local origin for the first farmers of central Anatolia.”
    https://www.biorxiv.org/content/early/2018/09/20/422295

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