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Thread: Living DNA new chip "Sirius"

  1. #1
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    Living DNA new chip "Sirius"

    I have forwarded to their helpdesk the problem with my Y-DNA haplogroup and got this interesting reply :

    "I passed this information on to our science team, and they have now got back to me.

    It is an exciting time here at Living DNA, as we have just begun using a new and improved chip on which to test your DNA - in fact, your sample was in one of the first two batches to be tested on the new chip. This means that we have had to develop new processes to analyse the data. As with all new scientific and technical endeavours, there are sometimes teething problems!

    The science team have identified an issue with the way the I1 haplogroup was being called when our systems analysed the data.

    The good news is that we have now rectified the problem, and I am re-processing your results now. You may receive some emails from us about the status of your test as this is being done - please ignore these as they are automatic."

    There is about 660 000 values in the Raw data at the moment.

    # Living DNA customer genotype data download file version: 1.0.2
    # File creation date: 10-10-2018
    # Genotype chip: Sirius

    Results Prior re-processing

    https://anthrogenica.com/showthread....l=1#post504873

    Results now

    now.png

    Slight change here. Some close admixture have to be interchangeable.

    Eastern Balkan dominate now. The 1.4% Iberia and 1.4% Western Russia are gone. Solid Germanic.

    But give me that re-processing switch as I can try and see all the different probabilities of admixture !
    Last edited by cercle; 10-12-2018 at 12:21 PM. Reason: new results after reprocessing

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  3. #2
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    Living DNA has moved from their Orion chip to Sirius?

    This should be interesting but I wish they'd concentrate on upgrading reference populations and rolling out DNA matching.
     
    Estimated ancestry after reviewing Ancestry.com, 23&Me, FTDNA My Origins, Living DNA and known family history:
    English 32%, Scottish 27%, Welsh 20%, Irish 16%, German/Netherlands/French 4%, Danish 1%

    Y-DNA leads to Isle of Skye, Scottish Highlands: R1b>M343>L278>L754>L389>P297>M269>L23>L51>L151/L11>P312>Z290>L21/M529>DF13>L513/DF1>S5668>A7>Z21253> S7834 > S7828 > BY11203 > BY11186 (about 320-550 years old)

    MTDNA leads to Glamorganshire, South Wales: K1a4a1f

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  5. #3
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    Duplicate...
     
    Estimated ancestry after reviewing Ancestry.com, 23&Me, FTDNA My Origins, Living DNA and known family history:
    English 32%, Scottish 27%, Welsh 20%, Irish 16%, German/Netherlands/French 4%, Danish 1%

    Y-DNA leads to Isle of Skye, Scottish Highlands: R1b>M343>L278>L754>L389>P297>M269>L23>L51>L151/L11>P312>Z290>L21/M529>DF13>L513/DF1>S5668>A7>Z21253> S7834 > S7828 > BY11203 > BY11186 (about 320-550 years old)

    MTDNA leads to Glamorganshire, South Wales: K1a4a1f

  6. #4
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    It looks like it is the case. Maybe an official announcement will come in the next few days. Yeah I wonder whether if it affects other developpment such as the ones you mention.

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  8. #5
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    Quote Originally Posted by cercle View Post
    It looks like it is the case. Maybe an official announcement will come in the next few days. Yeah I wonder whether if it affects other developpment such as the ones you mention.
    i hope they will update
    results of people who already tested with orion chip
    to sirius chip

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  10. #6
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    Quote Originally Posted by kingjohn View Post
    i hope they will update
    results of people who already tested with orion chip
    to sirius chip
    Yea its only fair. Considering 23andme hasn't though, this may not happen sadly.
    Known Ancestry: Albanian
    23andme results: 94% Balkan, 0.9% Italian, 0.8% Middle Eastern, 2.2% broadly southern European, 0.3 British & Irish, 0.3% Japanese, 0.5% unassigned
    MyOrigins2.0: 100% Southeast European
    MyAncientOrigins: 62% Farmer, 24% Hunter Gatherer, 14% Metal Age Invader
    MyHeritage: 76% Greek, 16% Balkan, 8% Italian
    WeGene: 99.5% Balkan, 0.5% unassigned
    GenePlaza: 92.7% East Mediterranean, 5.2% Southwestern European, 1.5% Ambiguous
    DNA.LAND: 95% Balkan, 5% Sardinian

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  12. #7
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    Quote Originally Posted by Dibran View Post
    Yea its only fair. Considering 23andme hasn't though, this may not happen sadly.
    Doubt it would make financial sense. I might upgrade mine myself if they reach Alpha Centauri.
    YSEQ:#37; YFull: YF01405 (Y Elite 2013)
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    Hidden Content

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  14. #8
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    It wouldn't make financial sense but they did promise free updates, not that I actually expect to do it because of what they said in the past.
    Ancestry: Ireland (Roscommon, Galway, Mayo)
    Paternal ancestor (Y): Martin Kelly b. c1830 in Co. Roscommon (Uí Maine/Hy Many)
    Father's mtDNA: Catherine Fleming b. c1831 in Co. Roscommon (H27e)
    Maternal ancestor (mt): Anne McDermott b. c1814 in Co. Roscommon
    Paternal great grandfather (mt): Mary Connella b. c1798 in Co. Roscommon (T2a1a8)

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  16. #9
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    i have both in cautious mode and in standard mode
    this
    :

    Europe (unassigned) 2.4%
    When calculating your ancestry we've identified some DNA that is found in multiple areas of Europe.
    These have been listed as "Unassigned", since we cannot pinpoint as confidently, specifically which regions that DNA is similar to. As our methods improve you will see your results updated and a lower proportion of Unassigned appearing.


    p.s
    i hope they will solved it
    only in complete mode it turn to something 2.4% iberia but they are not sure about it
    maybe with this new chip or futuer updates .......

  17. #10
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    One wonders what they have changed with the new chip.

    Guessing it is still GSA-based, which means that there's only so much that can be done. Hopefully they've fixed some of the Y-SNPs that were called wrongly on the old chip, and chosen equivalents instead.

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