Page 1 of 2 12 LastLast
Results 1 to 10 of 19

Thread: 23andme Y haplogroup: dubious results

  1. #1
    Registered Users
    Posts
    20
    Sex
    Location
    France
    Ethnicity
    French
    Nationality
    French
    Y-DNA
    G-CTS4803*

    23andme Y haplogroup: dubious results

    23andme has predicted that my Y haplogroup is G-Z30771.

    I have downloaded the raw data of 23andme, and had a look at my Y chromosome:

    -First checking: as Z30771 is a subclade of CTS4803, I have first searched for CTS4803.

    In genetichomeland.com I have found the following information:

    CTS4803: 15833180 (hg19) G (Anc) A (alt)

    And in my file: 15833180 A

    First checking OK.

    -Second checking: I have searched for my terminal subclade Z30071.

    In genetichomeland.com I have found the following information:

    Z30771 : 23632194 (hg19) C (Anc) T (alt)

    And in my file: i705237 Y 23632194 --


    What a shame! There is no call for the 23632194 SNP position and despite this 23andme put me in this subclade!

  2. The Following User Says Thank You to Phil1973 For This Useful Post:

     aaronbee2010 (10-16-2018)

  3. #2
    Registered Users
    Posts
    2,040
    Sex

    Will you try the tool here and Save Displayed Table as a CSV then rename the file with an of TXT then attach it here?

  4. #3
    Registered Users
    Posts
    2,040
    Sex

    I figured out what the problem is.....

    The ISOGG 2015 tree at https://isogg.org/tree/2015/ISOGG_HapgrpG15.html has Z30771, Z3441^, Z16029.2 as equivalents with the longhand name of G2a2b2a1a1b1a2a2

    23andme tests for Z3441 which is rs778087854 position 22063860. The mutation is A to C.

    23andme uses the first SNP in the group of phylogenetic equivalents even if the specific SNP is not tested.

  5. #4
    Registered Users
    Posts
    20
    Sex
    Location
    France
    Ethnicity
    French
    Nationality
    French
    Y-DNA
    G-CTS4803*

    Hello,

    Ref attached my 23andme Y results.

    According to YFull: Z3441 is on the same level as CTS4803, not Z30771.
    Attached Files Attached Files

  6. The Following User Says Thank You to Phil1973 For This Useful Post:

     ArmandoR1b (10-17-2018)

  7. #5
    Registered Users
    Posts
    20
    Sex
    Location
    France
    Ethnicity
    French
    Nationality
    French
    Y-DNA
    G-CTS4803*

    Attached the results after having processed my raw data with your tool.
    Attached Files Attached Files

  8. The Following User Says Thank You to Phil1973 For This Useful Post:

     ArmandoR1b (10-17-2018)

  9. #6
    Registered Users
    Posts
    20
    Sex
    Location
    France
    Ethnicity
    French
    Nationality
    French
    Y-DNA
    G-CTS4803*

    Just a remark: thanks to your tool I have noticed that I have been tested negatively for Z17787 (subclade of Z30771) and "Not Tested or No Call" for Z30771.

    Apparently Z6150 is equivalent to Z30771, but not present in the file.

    So as far as I can see, there is no reason to put me in the subclade Z30771.

  10. The Following User Says Thank You to Phil1973 For This Useful Post:

     ArmandoR1b (10-17-2018)

  11. #7
    Gold Class Member
    Posts
    340
    Sex
    Location
    Ohio
    Ethnicity
    German
    Nationality
    Galactic Empire
    Y-DNA
    R-Z324, Z5055, L188+
    mtDNA
    H5

    Some of the reads are unreliable. If 23andMe didn't report it then they know that location is not consistently called across samples. THis is the problem with SNP chips. Don't rely on just looking at your personal results and believe they are 100% accurate.

  12. The Following User Says Thank You to Cofgene For This Useful Post:

     Táltos (01-18-2019)

  13. #8
    Registered Users
    Posts
    2,040
    Sex

    Quote Originally Posted by Cofgene View Post
    Some of the reads are unreliable. If 23andMe didn't report it then they know that location is not consistently called across samples. THis is the problem with SNP chips. Don't rely on just looking at your personal results and believe they are 100% accurate.
    Will you give us examples of what you are mentioning? I have identified a few but need more if more have been found.

  14. The Following User Says Thank You to ArmandoR1b For This Useful Post:

     Táltos (01-18-2019)

  15. #9
    Registered Users
    Posts
    2,040
    Sex

    Quote Originally Posted by Phil1973 View Post
    Hello,

    Ref attached my 23andme Y results.

    According to YFull: Z3441 is on the same level as CTS4803, not Z30771.
    Quote Originally Posted by Phil1973 View Post
    Just a remark: thanks to your tool I have noticed that I have been tested negatively for Z17787 (subclade of Z30771) and "Not Tested or No Call" for Z30771.

    Apparently Z6150 is equivalent to Z30771, but not present in the file.

    So as far as I can see, there is no reason to put me in the subclade Z30771.
    23andme doesn't use the YFull tree. They use an outdated ISOGG tree. The placement of Z30771 changed in 2016 or 2017. 23andme should be using the 2017 tree but for a long time 23andme has been a follower in Y-DNA testing and not a leader so they aren't up to date with the phylogeny. It's wrong but it is what it is. In 2015 Z3441 was a phylogenetic equivalent of Z30771. All I can do is explain the reasoning behind your result at 23andme.

    The tool reports all of the RSIDs and positions included in the raw data. If an SNP isn't found it isn't tested or was not in the 2017 ISOGG tree. Z6150 is position 7081962 in hg19/gr37. That position is not included in the raw data by 23andme.

    No one at 23andme is tested for Z30771. There is a column, in the results of the tool that I updated, named Tested that tells you if the SNP is tested for not. None of the more than 12 kits that I have looked at have a result for i705237 so that rsid has No in the Tested column.

  16. The Following User Says Thank You to ArmandoR1b For This Useful Post:

     Táltos (01-18-2019)

  17. #10
    Registered Users
    Posts
    20
    Sex
    Location
    France
    Ethnicity
    French
    Nationality
    French
    Y-DNA
    G-CTS4803*

    OK thanks, so for the final verdict I will have to wait for my Yseq results (G superclade).

    Thomas Krahn wrote to me:

    "While the 23andMe chip uses a fixed selection of Y SNPs, we use discrete DNA testing of all Y-SNPs that are currently known and available for testing. Our panels are updated every few months and we are open for suggestions to add new SNPs to our panels as long as the testing hasn't been completed. This makes sure that we are identifying your position on the Y tree as precise as it is technically possible. In the most cases this is several levels downstream from what the fixed 23andMe chip provides. We are actively involved in the scientific research of the Y chromosome phylogeny and we contribute our services to ISOGG."

    It seems to be more serious.

  18. The Following 2 Users Say Thank You to Phil1973 For This Useful Post:

     MacUalraig (10-17-2018),  Táltos (01-18-2019)

Page 1 of 2 12 LastLast

Similar Threads

  1. 23andMe Haplogroup v5 chip
    By anderson.clayton in forum 23andMe
    Replies: 14
    Last Post: 10-10-2018, 12:11 PM
  2. Inaccurate 23andMe Haplogroup results
    By ajc347 in forum 23andMe
    Replies: 31
    Last Post: 08-05-2018, 11:21 PM
  3. 23andme 's new Paternal Haplogroup Report
    By sgdavies@hotmail.com in forum 23andMe
    Replies: 23
    Last Post: 09-16-2017, 12:10 PM
  4. Scottish Clans and Dubious Histories
    By castle3 in forum General
    Replies: 110
    Last Post: 08-01-2017, 01:53 AM
  5. Replies: 30
    Last Post: 09-22-2016, 06:30 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •