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Thread: Question about 23andme Discrepancy

  1. #1
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    Question about 23andme Discrepancy

    Ok, so I have tested my 23andme raw data pretty widely, and except for 23andme, I get the same result at all places:

    Eurogenes K15 = 52.74% SSA, 9.18% East Asian + Native American, 38.08% Euro

    Eurogenes K13 = 52.4% SSA, 9.54% East Asian + Native American (East Asian), 38.06% Euro

    Eurogenes K12 = 52.18% SSA, 9.07% East Asian + Native American, 38.75% Euro

    Eurogenes K12b = 52.28% SSA, East Asian 9.24%, 37.96% Euro

    Eurogenes K11 = 52.2% SSA, East Asian + Native American, 38.5% Euro

    Eurogenes K10 = 52.2 SSA, 9.3% East Asian + Native American, 38.5% Euro

    Eurogenes K9 = 52.2% SSA, 9.32% East Asian + Native American, 38.48% Euro

    Eurogenes K9b = 51.27% SSA, 10.34% East Asian, 38.39% Euro

    McDonald = 53.1% SSA, 8.8% East Asian, 38.1% Euro

    FTDNA = 52.8% SSA, 9.1% East Asian, 38.1% Euro

    Dodecad World9 = 51.55% SSA, 9.78% East Asian, 38.67% Euro

    Dodecad K7 = 52.5% SSA, 9.03% East Asian, 38.47% Euro

    Dodecad K12 = 53.04% SSA, 9.12% East Asian, 37.84% Euro

    Harrapa = 52.83% SSA, 8.84% East Asian, 38.33% Euro

    DNA Tribes = 51.7% SSA, 9.2% East Asian, 39.1% Euro

    These results were all generated with 23andme raw data. As you can see, they are all, more or less, within a tight 1% range.

    ----------------------------------------------------------------------------------------

    23andme = 58% SSA, 8% East Asian, 34% Euro

    Honestly, I am quite surprised by this result since it deviates from all of the other results by a statistically meaningful amount. What do you guys think? Also, with the update coming at 23andme, do you think it like that my 23andme results will converge with the pack?
    Last edited by cyna; 11-23-2013 at 01:55 AM.

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    I haven't seen such consistent results before. Count yourself lucky I suppose. Some of ours vary wildly with each service. There's a significant difference in my results even between Eurogenes calculators.

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    One difference might be the populations used as reference samples. 23andMe has added quite a few samples based on the Where Are You From? survey.

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    They also just added a whole host of new populations and are undertaking a re-computation. Chance that 23andme will converge on the rest? The population sets are the same ones used by the others from what I understand.

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    Quote Originally Posted by Dr_McNinja View Post
    I haven't seen such consistent results before. Count yourself lucky I suppose. Some of ours vary wildly with each service. There's a significant difference in my results even between Eurogenes calculators.
    I agree (and I confirm) : your results are amazingly similar with the different calculators.

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    Except for 23andme

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    As has been pointed out before, the 23andMe AC is not intended to do exactly the same thing as the Eurogenes or Dodecad utilities.

    AC is not just counting SNPs. It looks at windows of SNPs in an attempt to assign some identity to them, an identity within a timeframe that has historical meaning for people today. Then runs of windows are smoothed, which will tend to reduce traces of older ancestry. The design goal of the algorithm is summarized in the "500 years" phrase which often appears to be misunderstood.

    Even with all of that, your 23andMe results do not differ much from the admixture calculators.
    Last edited by S9 H9; 12-02-2013 at 12:43 AM.

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    I second S9 H9 on this. Also, 23andMe has some East African samples to power the "Sub-Saharan African" category. This probably explains the higher African percentage at 23andMe, since some of your West Eurasian ancestry is being absorbed into that category.

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