Nebula Genomics

[Adamm]

As far as I understand it's only "deep" because it includes haplogroups.

I am expecting my results in about a month and if the partnership is completed by then I might even skip Yfull for now. I think exploring my bigY will keep me entertained for a while.

Believe me, you wanna upload on Yfull. YFULL is going to become the main thing in the future because WGS is becoming cheaper and cheaper, I did DanteLabs and uploaded on YFULL and I know a lot more who did the same. BigY stats 600$ while with WGS you can get it for 150$ (on discount days) and 300$ on normal days. Especially since you're E-M183 I hope you'll upload on Yfull, it will be good for the development of the tree.

[digital_noise]

I agree. Even though you are nowhere near me in the E tree, it’s nice to have as many E’s as we can get.

[Brumcho]

has anyone successfully converted their Nebula VCF to 23andMe file? I used the instructions on Nebula's blog using VCF-to-23andMe and neither FTDNA nor LivingDNA can process the file.

[digital_noise]

has anyone successfully converted their Nebula VCF to 23andMe file? I used the instructions on Nebula's blog using VCF-to-23andMe and neither FTDNA nor LivingDNA can process the file.

I managed to get my .4x coverage .vcf converted to 23 and me format. I had to basically combine it with another raw file to get it to upload. I only uploaded it to Gedmatch though, didn’t try any other places.

[aaronbee2010]

has anyone successfully converted their Nebula VCF to 23andMe file? I used the instructions on Nebula's blog using VCF-to-23andMe and neither FTDNA nor LivingDNA can process the file.

If the Nebula VCF only contains positions with variants relative to the reference genome (and not positions that match the reference genome), you won't get much mileage with the Nebula VCF alone. You can follow my instructions posted previously on this thread, assuming you have a Windows PC with a decent specification (adjust the no. of threads used by samtools to be around 1/2 to 3/4s of the total no. of threads your CPU has).

[Brumcho]

If the Nebula VCF only contains positions with variants relative to the reference genome (and not positions that match the reference genome), you won't get much mileage with the Nebula VCF alone. You can follow my instructions posted previously on this thread, assuming you have a Windows PC with a decent specification (adjust the no. of threads used by samtools to be around 1/2 to 3/4s of the total no. of threads your CPU has).

thank you it worked and took about hour and a half. I did see that post yesterday but blew past it for some reason while racking my brain

So far FTDNA and LivingDNA rejected the combined kit file but accepted the 23andmeV3 version. GedMatch took the combined to my surprise.

[Ibericus]

***All 30x whole-genome sequencing purchases will receive access to an ancestry experience/results, but this feature will not be LIVE or accessible until the end of 2020.***

https://nebulagenomics.zendesk.com/h...llation-Policy

[aaronbee2010]

Nebula have now started offering 100x WGS for $999 (not including membership fees) alongside their standard 30x service. Maybe pmokeefe is interested?

https://nebula.org/whole-genome-sequencing/

[jadegreg]

Going to be saving my pennies for a while on that one..........not quite the savings I was expecting

[pmokeefe]

Nebula have now started offering 100x WGS for $999 (not including membership fees) alongside their standard 30x service. Maybe pmokeefe is interested?

https://nebula.org/whole-genome-sequencing/

Received an email from Nebula with the offer that also said:

Already got 30x Whole Genome Sequencing? You can upgrade to 100x coverage without submitting a new sample! Contact us at [email protected] to learn more (please also share your sample ID).

I responded about the upgrade, this was their reply ...

Hey there,

Thanks for reaching out to Nebula Support, happy to help! If you previously received your 30x results, then we will need to confirm that your sample still has enough DNA to be resequenced again before upgrading.

If you have purchased within the last 30-days and your sample has not entered 30x sequencing yet, we can simply upgrade you by sequencing your data at 100x.


The upgrade fee will be $700. If you're interested please just let us know and my team will invoice you an upgrade charge.

Thanks so much,

Nebula Support

Are their any issues with resequencing a sample?