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Thread: Fraud and frequent preprocessing in Genetic data

  1. #1
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    Post Fraud and frequent preprocessing in Genetic data

    Some ethnicities are known to be emotional about Genetic data so resort to pre-processing & post-processing of the genetic data from the test results. These processing are done to remove certain ethnic SNPs from their data. This may be ok as long as the government rules and legislation don't catch them. Say if the genetic tests are used in health data here are the cases that can be filed.

    Laboratory Fraud
    Clinical laboratories and independent diagnostic testing facilities referred to as IDTFs have often been defendants in False Claims Act cases brought by whistleblowers. Common types of fraud by laboratories and IDTFs include:


    Billing tests that were performed by unlicensed personnel, or misrepresenting who performed the test.
    Y: H-M69 -> H-M82 -> SK1225 -> H-Z5888 -> H-Z5890 -> H-CTS8144 [CTS8144/PF1741/M5498] -> Z34531 (H1a1a4b3b1a8~)
    mtDNA: U2a1a
    extras 309.1C 315.1C 522.1A 522.2 CG8572A G8860A T11368C T16093a T16154C C16519T C195T

    G25 Ancients Dist 0.99 Shahr_I_Sokhta_BA3:S8728.E1.L1 65.2 Saidu_Sharif_IA_o:S7722.E1.L1 17.8 Udegram_IA:I1985 7.8 Jordanian:S_Jordanian-1 4.4 Barikot_IA:I6545 2.2 Scotland_N:I26602 Narva_Lithuania: Donkalnis6

    Lactose persistance rs3213871 rs4988243

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  3. #2
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    How do you know about this?

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    Quote Originally Posted by Kulin View Post
    How do you know about this?
    Based on published test results from test studies on the communities vs. the variations shown in the calc results & g25 & validated by phenotype

    Outliers can be spotted easily & accounted for based on the possible additions in the populations
    Last edited by tipirneni; 03-31-2019 at 04:45 PM.

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    What reason would someone have for doing this?

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    Quote Originally Posted by Censored View Post
    What reason would someone have for doing this?
    Many subcaste groups in India believe that they were pure etc... or they used to higher status etc... so remove the Dalit SNPs using pre-processing & add some Aryan SNPs to make a statement. So they will be doing it. There are also instances of newly converts claiming relation to Syeds etc.. among muslims.

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    Quote Originally Posted by tipirneni View Post
    Many subcaste groups in India believe that they were pure etc... or they used to higher status etc... so remove the Dalit SNPs using pre-processing & add some Aryan SNPs to make a statement. So they will be doing it. There are also instances of newly converts claiming relation to Syeds etc.. among muslims.
    How would it affect SNPs analyzed by DNA companies?

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    Quote Originally Posted by tipirneni View Post
    Based on published test results from test studies on the communities vs. the variations shown in the calc results & g25 & validated by phenotype

    Outliers can be spotted easily & accounted for based on the possible additions in the populations
    Can you give an example in relation to g25?

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    Quote Originally Posted by 26284729292 View Post
    Can you give an example in relation to g25?
    Good question. I m seeing many G25 coordinates missing some data. But right now it beyond scope of this Thread.
    Y: H-M69 -> H-M82 -> SK1225 -> H-Z5888 -> H-Z5890 -> H-CTS8144 [CTS8144/PF1741/M5498] -> Z34531 (H1a1a4b3b1a8~)
    mtDNA: U2a1a
    extras 309.1C 315.1C 522.1A 522.2 CG8572A G8860A T11368C T16093a T16154C C16519T C195T

    G25 Ancients Dist 0.99 Shahr_I_Sokhta_BA3:S8728.E1.L1 65.2 Saidu_Sharif_IA_o:S7722.E1.L1 17.8 Udegram_IA:I1985 7.8 Jordanian:S_Jordanian-1 4.4 Barikot_IA:I6545 2.2 Scotland_N:I26602 Narva_Lithuania: Donkalnis6

    Lactose persistance rs3213871 rs4988243

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  17. #9
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    Quote Originally Posted by tipirneni View Post
    Some ethnicities are known to be emotional about Genetic data so resort to pre-processing & post-processing of the genetic data from the test results. These processing are done to remove certain ethnic SNPs from their data. This may be ok as long as the government rules and legislation don't catch them. Say if the genetic tests are used in health data here are the cases that can be filed.

    Laboratory Fraud
    Clinical laboratories and independent diagnostic testing facilities – referred to as IDTFs – have often been defendants in False Claims Act cases brought by whistleblowers. Common types of fraud by laboratories and IDTFs include:


    Billing tests that were performed by unlicensed personnel, or misrepresenting who performed the test.
    While the first portion you said is true for some who doctor their results superficially on boards, the rest of what you wrote makes no sense and its a rather sweeping and ridiculous statement. None of the DNA testing companies are hinged on pandering to emotions for any ethnic group lol, modern populations cluster with their respective ethnic groups using any software whether its Davidski's G25, Poi's checkfit, PAST, qpAdm , F3 stats. We have seen that a gazillion times over on this forum.

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    This sounds like the Cracked.com "article" re-warmed. I was shocked to find that in wake of the "Fake News" trend many, many people on online communities including Reddit, ISOGG FB group etc. consider Cracked.com which bills itself as "America's Only Humor Site" as legitimate, trusted breakign news site - at least as long as the articles confirm their beliefs.

    The "Inside The Shady World Of DNA Testing Companies" article is so riddled with contradictions (Secret informant claims both to have been working there when tests were introduced, and that they weren't yet working there when angry cutomer attacked them, for example) and technical whoopers (Claiming that DNA tests require using mouthwash to purify your DNA, when it's explicitly forbidden by all DTC genetic testing companies etc.) that it's a wonder anybody can read it without their heads exploding. But it's become staple lore among everybody who disagrees with ancestry estimates for whatever reason.

    At the same time these accusations are always tricky, because anybody anywhere can set up shop and start selling DNA ancestry tests that are completely made up. There are threads on LivingDNA forums right now about how LivingDNA is changing people's ancestry estimates to match after they've contacted customer service. However, for any DNA testing compay which offers one-to-one matching to DNA relatives, doctoring actual DNA results would be immediately obvious when people don't match their relatives. And at least the major American DNA testing companies have no conceivable motive for tweaking ancestry analysis according to some country's internal divisions, which I've seen alleged in the past when people don't agree with their results.

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