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Thread: On Ancient Egyptian DNA.

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    On Ancient Egyptian DNA.

    5kXCtde.jpg

    Courtesy of a thread on Eupedia, there's confirmation that Djehutynakht, a mummy whose head was tested for mtDNA was also tested for nuclear DNA.

    This is important since the mummy is:
    A. An overseer.
    B. Early Middle Kingdom that predates foreign rule of Egypt.
    C. A finding in Upper Egypt.

    Now, what do you expect to be found?

    I hope the mummy is part of a wider study with more than one sample that's no younger than 2000 B.C.

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    Quote Originally Posted by Adules View Post
    5kXCtde.jpg
    a mummy whose head was tested for mtDNA
    Test result out yet?

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    The haplotype (deposited in GenBank under accession number MG736653) belongs to mitochondrial DNA lineage U5b2b5, but the specific sequence has not been previously reported in the 35,942 mtGenomes stored in the NCBI GenBank database (as of October 2017). The sequence closest to the mummy’s belongs to a contemporary individual from Lebanon (KT779192 [67]); however, the two haplotypes still differ at five positions, three of them in the control region (CR). A comparison between the mummy CR and the 26,127 CR sequences from the EMPOP database produced no match.
    To better understand the mtDNA lineage of the mummy in the context of known Egyptian mtDNA diversity, the mummy haplogroup was compared to the mtDNA haplogroup distribution of 668 Egyptians from various modern populations [68,69,70,71,72,73]. The dominant haplogroups among this dataset were haplogroup T (11.98%) and L3 (11.23%; Table S3). Out of the 64 individuals who belonged to haplogroup U, seven belonged to haplogroup U5 (1.05%), and three (0.5%) belonged to one of the U5b subgroups (U5b1c; U5b1d1a; U5b2a5).
    The Djehutynakht sequence was also compared to available ancient human DNA sequences (Table S4). Not surprisingly, no direct matches to the Djehutynakht sequence have been reported. However, related U5b2b sequences have been observed in ancient human remains from Europe, and a haplogroup U5b2c1 haplotype was recently discovered in 2000-year-old remains from Phoenicia [67]. When only the mtDNA sequences recovered from ancient Egyptian human remains are considered, the Djehutynakht sequence most closely resembles a U5a lineage from sample JK2903, a 2000-year-old skeleton from Abusir el-Meleq [74].
    That is pretty interesting.

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    Quote Originally Posted by epoch View Post
    That is pretty interesting.
    Somewhat surprising. I was expecting common North African haplotypes like U6 or M1.

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    More impressive since the mummy was an overseer in Upper Egypt during the Early Middle Kingdom (before it became more open to foreigners).

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    I wouldn't be surprised to see him cluster with Copts, but I'm keeping an open mind. What I want to know is if the relationship between Egypt and its southern neighbors was clinal (as I would personally expect) or if we get something more like what we see in the Caucasus with strong differentiation between Maykop and steppe populations north of the mountains. But as far as I know there's no such barrier to gene flow along the Nile so a strong boundary is unlikely. If Nubians were already Beja-like in prehistoric and dynastic times it would be hard for me to believe that contemporaneous Upper Egyptians had only marginal SSA ancestry. We'll see.
    Ελευθερία ή θάνατος.

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    I hope the mention of Henu's tomb confirms we're getting other samples than just Djehutynakht's.

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    How representative would you all call that mummy?

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