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Thread: Usefulness of Higher Density SNP Testing in Autosomal Matching

  1. #1
    Registered Users
    Wisconsin, USA
    Y-DNA (P)
    mtDNA (M)

    Ireland England Netherlands Germany France

    Usefulness of Higher Density SNP Testing in Autosomal Matching

    While reviewing the products offered on IrelandsDNA, I noticed that their autosomal tests cover 3-4x the number of SNPs as their competitors now that most of them have switched over to the V4 chips. What they don't offer is any form of tool to compare with others. This has me wondering... Is there a benefit for autosomal relative matching by testing out to this level if something like GedMatch allowed uploads and comparison? Would the higher density decrease or increase the likelihood of IBS on shorter shared segments?

    If anyone has some pointers to some good papers on this, I'd love to take a look.

  2. The Following User Says Thank You to JamesKane For This Useful Post:

     AJL (01-03-2014)

  3. #2
    Registered Users
    Mixed Euro/Near East
    Y-DNA (P)
    mtDNA (M)

    Canada Franco-Manitoban European Union Ottoman Empire Russia Imperial United States Grand Union
    Looking at several close relatives in combination, I can safely say that it's possible a fair proportion of current "matches" would not stand up to the scrutiny of denser testing and/or proper phasing, though this also depends on levels of endogamy, for example.

    Whether the denser testing at IDNA/BDNA/SDNA would actually compensate for this meaningfully, I don't know; also, since has to allow for various platforms, I wouldn't think uploading denser results would eliminate any false matches there because you would still be matching at the resolution of the lowest level tested. In effect, this might be compared to upgrading your RAM to the highest level possible while keeping a primitive CPU and hard drive: you probably won't see benefits.

    Other ancestral Y lines:

    E1b-M81 Ukraine (Ashkenazi)
    E1b-V13 England
    I1-M253 Ireland
    I2-M423 Ukraine
    R1a-L176.1 Scotland
    R1b-L584 Syria/Turkey (Sephardi)
    R1b-L20 Ireland
    R1b-L21 (1)England; (2)Wales?>Connecticut
    R1b-L48 England
    R1b-P312 Scotland
    R1b-FGC32576 Ireland

    Other ancestral mtDNA lines:

    H1b2a Ukraine (Ashkenazi)
    H6a1a3 Ukraine
    K1a9 Belarus (Ashkenazi)
    K1c2 Ireland
    V7a Ukraine

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