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Thread: Phylogenetic Structure of Q-M378 Subclade Based On Full Y-Chromosome Sequencing

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    Phylogenetic Structure of Q-M378 Subclade Based On Full Y-Chromosome Sequencing

    Vladimir Gurianov, Leon Kull, Roman Sychev, Vladimir Tagankin, Vadim Urasin

    Phylogenetic Structure of Q-M378 Subclade Based On Full Y-Chromosome Sequencing

    Q-M378 subclade, which is downstream of Q-L275 haplogroup, is marked by a wide area of its distribution and a minor share of presence in modern populations of Eurasia. Phylogenetic structure of the subclade, known so far, did not allow for matching SNP Y-chromosomes to specific populations and to reconstruct possible directions of their migrations in retrospect.

    The conducted research enabled us to form a consistent phylogenetic structure of Q-M378 subclade, validated by analysis of SNP and STR-markers, based on the data of full Y-chromosome sequencing using next generation sequencers. As part of the research, new phylogenetic levels of Q-Y2250 (downstream of Q-M378 and including Q-L301), Q-Y2220 (downstream of Q-L245), Q-
    Y2200 (downstream of Q-Y2220) were defined.

    SNPs, which, in the future, may possibly mark certain European and Asian subclusters of Q-Y2220 (including the Armenian subcluster), as well as separate branches of the Jewish cluster Q-Y2200, were defined as well.

    The research also confirmed connection of Q-M378 subclade distribution with migration of Indo-European language carriers from Central Asia via Afghanistan and Iran to the West.
    http://rjgg.org/index.php/RJGGRE/article/view/134
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     BMG (02-23-2014),  Humanist (01-08-2014),  Tįltos (01-09-2014)

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    Шад very well done! Thank you so much, this article really made my night. And may we continue to learn more about our haplogroup in the future.

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    Last edited by Шад; 01-11-2014 at 12:19 PM.
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    Quote Originally Posted by Шад View Post
    Thank you, this is wonderful! Graphs, maps, and pictures always enhance my understanding of something. Maybe can be used in a DNA project?

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    is there some way to calculate the age of Q-L275 and subclades with these data?

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    Quote Originally Posted by bicicleur View Post
    is there some way to calculate the age of Q-L275 and subclades with these data?
    This is in our plans for the future.
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    ISOGG SNP tree (update)
    Hg Q
    http://www.isogg.org/tree/ISOGG_HapgrpQ.html
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    Quote Originally Posted by Шад View Post
    That is awesome! Please advise me in the future which SNPs I should test my brother for.

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    New article on Q1b
    The new data of full Y-chromosome sequencing allowed the update of the Q1b (Q-L275) haplogroup struc- ture, as well as in identifying new subclades: Q-Y2990 (downstream Q-Y2250), Q-Y2225 (downstream Q-Y2220) and Q-Y3030 (downstream Q-Y2200). It created the background for continuation of further researches of the in- ner structure of the pointed subclades and on comparing of their existing ethno-population composition with the migration of the Indo-European tribes.
    https://www.academia.edu/7117246/The...ome_sequencing

    A big thank you to Dr. Gurianov and his colleagues! Excellent work!

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    Shad asked me to cross-post this in our discussion of Q1b:

    Quote Originally Posted by Tįltos View Post
    I saw that too. I hope that person decides to test further it would be interesting to see.
    Quote Originally Posted by Humanist View Post
    I believe that he had a Big Y test done last month. Shad is analyzing the results. Looking forward to reading about what he has learned from the data.
    Here is what Shad had to say regarding the results:

    [The Assyrian's] SNPs divide Y2220 cluster

    He is Y2228+ Y2209-

    Assirian Q1b probably form new subbranch under L245 and ex-Y2200 branches.


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