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Thread: COVID-19 (no politics)

  1. #1
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    COVID-19 (no politics)

    Third thread about the Covid-19 with no politics I hope this time.


    I have a question regarding Ancient DNA, since scientist/ biologist /anthropologist already have many unpublished samples, can't they work at home ?

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    Quote Originally Posted by Dieu View Post
    Third thread about the Covid-19 with no politics I hope this time.

    . . .
    Good luck with that. Honestly, good luck.

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    Quote Originally Posted by rms2 View Post
    Good luck with that. Honestly, good luck.
    Yep.

    Are we going to simply discuss the genetics of the virus, or relay daily news? If it’s the latter it will be in some way inseparable from the many ticks.

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    Quote Originally Posted by spruithean View Post
    Yep.

    Are we going to simply discuss the genetics of the virus, or relay daily news? If it’s the latter it will be in some way inseparable from the many ticks.
    I plan to stay out of it altogether except for periodic check-ins to see if what I think will happen does in fact happen.

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    Quote Originally Posted by rms2 View Post
    Good luck with that. Honestly, good luck.
    I don't care about politics but I don't want admins to go crazy and close this thread, rules are rules unfortunately. And The pandemic is global, speaking about one specific country Covid-19 politics is almost meaningless.

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    What about SNP rs4804803? It is mentioned those with AG and GG have some protection against SARS, which is a similar corona virus to COVID 19.

    SARS Coronavirus
    DC-SIGN shares 77% amino acid similarity with CLEC4M, the usual binding receptor for the SARS coronavirus (SARS-CoV) [PMID 10975799]. It was found to interact with the spike protein of the virus, facilitating viral transmission to susceptible cells [PMID 15140961OA-icon.png].
    SARS patients with a -336G-positive genotype (either AG or GG) have a 2.5-fold greater chance of having lower lactate dehydrogenase (LDH) levels compared with -336AA patients (one SNP tested; significance threshold = 0.05; p = 0.014) [PMID 20359516]. High LDH levels are known to be an independent predictor for poor SARS clinical outcome, possibly because of the increased tissue destruction that is the result of immune hyperactivity [PMID 20359516]. Thus, SARS patients with the AA genotype have a 60% greater chance of a poor prognosis than GG or AG patients [PMID 20359516].

    https://www.snpedia.com/index.php/rs4804803

    I am AA, unfortunately open for infection.

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    Quote Originally Posted by eastara View Post
    What about SNP rs4804803? It is mentioned those with AG and GG have some protection against SARS, which is a similar corona virus to COVID 19.

    SARS Coronavirus
    DC-SIGN shares 77% amino acid similarity with CLEC4M, the usual binding receptor for the SARS coronavirus (SARS-CoV) [PMID 10975799]. It was found to interact with the spike protein of the virus, facilitating viral transmission to susceptible cells [PMID 15140961OA-icon.png].
    SARS patients with a -336G-positive genotype (either AG or GG) have a 2.5-fold greater chance of having lower lactate dehydrogenase (LDH) levels compared with -336AA patients (one SNP tested; significance threshold = 0.05; p = 0.014) [PMID 20359516]. High LDH levels are known to be an independent predictor for poor SARS clinical outcome, possibly because of the increased tissue destruction that is the result of immune hyperactivity [PMID 20359516]. Thus, SARS patients with the AA genotype have a 60% greater chance of a poor prognosis than GG or AG patients [PMID 20359516].

    https://www.snpedia.com/index.php/rs4804803

    I am AA, unfortunately open for infection.
    Yikes, fellow AA here
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    AA, first person to come back with a G has to bring me food

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