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Thread: Paper: Uncanny similarities of 2019-nCoV to HIV-1

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    Paper: Uncanny similarities of 2019-nCoV to HIV-1

    This is a paper from the month of January. Apologies if it has already been posted.

    Abstract:
    We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019- nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.

    Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gagp

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    Quote Originally Posted by Ibericus View Post
    . . . The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature . . .
    So, if that is unlikely to be fortuitous, that means it is likely to have occurred by design, right?

    In other words, COVID-19 could be a virus designed by some humans. Hmmm . . .

    No desire to become involved in another COVID-19 political thread, but that is interesting. Of course, I'm not scientist enough to pass judgment on it; I just thought it was worthy of note.
    Last edited by rms2; 04-30-2020 at 06:48 PM. Reason: Awkward language

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    Quote Originally Posted by Ibericus View Post
    This is a paper from the month of January. Apologies if it has already been posted.

    Abstract:
    We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019- nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.

    Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gagp
    Wasn’t this paper pretty much disproven?

    https://www.factcheck.org/2020/02/ba...bioengineered/

    Note Bedford and several other experts are mentioned in the factcheck posting, https://mobile.twitter.com/trvrb/sta...37991168380928
    Last edited by spruithean; 05-02-2020 at 01:45 AM.

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