Page 1 of 44 12311 ... LastLast
Results 1 to 10 of 436

Thread: Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria[

  1. #1
    Gold Class Member
    Posts
    787
    Sex
    Location
    San Diego, CA
    Ethnicity
    Polish/British Isles
    Nationality
    U.S.
    Y-DNA (P)
    R-A9185
    mtDNA (M)
    H1
    mtDNA (P)
    J1c2

    Poland England Ireland Munster

    Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria[

    Extended Data Fig. 8: Bayesian phylogenetic tree relating Bacho Kiro Cave mtDNA to 54 present-day humans, 10 directly radiocarbon dated ancient H. sapiens and the Vindija 33.16 Neanderthal.

    Extended Data Table 2 mtDNA branch-shortening estimates

    Supplementary information
    These figures do not appear to be behind the Nature paywall, unlike the main article, unforuntately.

    Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria

    Data availability
    The data that support the findings of this study are available from the corresponding author upon reasonable request. Genetic sequence reads from all libraries and corresponding negative controls are deposited at European Nucleotide Archive under the study accession number PRJEB35466. The FASTA files of the mitochondrial genomes are deposited in GenBank with the accession numbers MN706602–MN706607. Details are as follows: Bacho Kiro AA7-738, MN706602; Bacho Kiro BB7-240, MN706603; Bacho Kiro BK-1653, MN706604; Bacho Kiro CC7-335, MN706605; Bacho Kiro CC7-2289, MN706606; and Bacho Kiro molar F6-620, MN706607.

    Supplementary Discussion 5: Palaeogenetics (Supplementary information)
    ...
    The reconstructed mtDNAs of Bacho Kiro Cave specimens were aligned to 54 present-day
    humans, 12 ancient H. sapiens (SI Tab. 9), 22 Neanderthals, four Denisovans, one Sima de los
    Huesos individual and a chimpanzee to determine to which hominin group they belong. All of the
    six Bacho Kiro Cave mitochondrial genomes fall within the variation of H. sapiens. The
    haplogroups of the reconstructed mtDNAs were identified using HaploGrep and the Phylotree
    database (build 17). Bacho Kiro Cave molar (F6-620) and specimen AA7-738 carry the
    substitutions that define the M haplogroup with 0.98 posterior support (73G, 263G, 489C, 750G,
    1438G, 2706G, 4769G, 7028T, 8701G, 8860G, 9540C, 10398G, 10400T, 10873C, 11719A,
    12705T, 14766T, 14783C, 15043A, 15301A, 15326G, 16223T), along with two substitutions
    (4730T and 5315G) not seen in any present-day human population. The specimens BB7-240 and
    CC7-335 carry the substitutions characteristic of the N haplogroup (73G, 263G, 750G, 1438G,
    2706G, 4769G, 7028T, 8860G, 9456G, 11719A, 12705T, 14766T, 15326G, 16223T) with 0.93 and
    0.92 posterior support, respectively. Both of them share two mutations (4113A, 8155A) not
    detected in any present-day human population along with one specific mutation for each of them
    (194T in BB7-240 and 14790G in CC7-335) and fall basal to the other individuals of the
    macrohaplogroup N, with the smallest number of differences to Oase1. Specimen CC7-2289
    carries the substitutions defining the R haplogroup (73G, 263G, 750G, 1438G, 2706G, 4769G,
    7028T, 8860G, 11719A, 14766T, 15326G) with no private mutations and no additional
    substitutions that define sub-clades of haplogroup R, suggesting a relationship to the mtDNA
    ancestral to present-day haplogroup R. The mitochondrial genome of the specimen BK-1653
    belongs to haplogroup U8, commonly found in other Upper Palaeolithic humans in Europe,
    and shows the smallest number of differences to the mtDNA genome of Kostenki 14.
    Last edited by pmokeefe; 05-11-2020 at 04:25 PM.
    YFull: YF14620 (Dante Labs 2018)

  2. The Following 27 Users Say Thank You to pmokeefe For This Useful Post:

     Agamemnon (05-11-2020),  Angoliga (05-15-2020),  Ariel90 (05-12-2020),  Artmar (05-18-2020),  Helen (05-11-2020),  Helgenes50 (05-12-2020),  J Man (05-11-2020),  J1 DYS388=13 (05-11-2020),  Lank (05-11-2020),  Lenny Nero (10-11-2020),  MacUalraig (05-13-2020),  Max_H (04-09-2021),  Megalophias (05-12-2020),  Michalis Moriopoulos (05-11-2020),  Milkyway (05-11-2020),  Onur Dincer (05-29-2020),  oz (05-11-2020),  Piquerobi (05-11-2020),  RCO (05-11-2020),  rms2 (05-11-2020),  rozenfeld (05-11-2020),  Ryukendo (05-12-2020),  Shuzam87 (04-09-2021),  siberoberingian (05-16-2020),  teepean47 (05-12-2020),  thejkhan (05-11-2020),  tipirneni (05-15-2020)

  3. #2
    Registered Users
    Posts
    309
    Sex
    Omitted

    mtDNA was all they could get?

  4. #3
    Gold Class Member
    Posts
    787
    Sex
    Location
    San Diego, CA
    Ethnicity
    Polish/British Isles
    Nationality
    U.S.
    Y-DNA (P)
    R-A9185
    mtDNA (M)
    H1
    mtDNA (P)
    J1c2

    Poland England Ireland Munster



    "Bayesian phylogenetic tree relating Bacho Kiro Cave mtDNA to 54 present-day humans, 10 directly radiocarbon dated ancient H. sapiens and the Vindija 33.16 Neanderthal."

    Courtesy of parasar.
    YFull: YF14620 (Dante Labs 2018)

  5. The Following 10 Users Say Thank You to pmokeefe For This Useful Post:

     Agamemnon (05-11-2020),  epoch (05-11-2020),  Helen (05-11-2020),  Lenny Nero (10-11-2020),  MacUalraig (05-13-2020),  Onur Dincer (05-29-2020),  parasar (05-12-2020),  RCO (05-11-2020),  rms2 (05-11-2020),  Ryukendo (05-12-2020)

  6. #4
    Gold Class Member
    Posts
    787
    Sex
    Location
    San Diego, CA
    Ethnicity
    Polish/British Isles
    Nationality
    U.S.
    Y-DNA (P)
    R-A9185
    mtDNA (M)
    H1
    mtDNA (P)
    J1c2

    Poland England Ireland Munster
    Quote Originally Posted by TuaMan View Post
    mtDNA was all they could get?
    Researchers then extracted DNA from these bones and the tooth and found that the mitochondrial sequences—the most abundant DNA in many fossils—were those of H. sapiens and related to those of people from Siberia, Spain, and China. The team is now analyzing the fossils’ nuclear DNA.
    Oldest Homo sapiens in Europe—and a cave bear pendant—suggest cultural link to Neanderthals
    YFull: YF14620 (Dante Labs 2018)

  7. The Following 10 Users Say Thank You to pmokeefe For This Useful Post:

     Agamemnon (05-11-2020),  Helen (05-11-2020),  Kale (05-12-2020),  Lenny Nero (10-11-2020),  Onur Dincer (05-29-2020),  parasar (05-12-2020),  rms2 (05-11-2020),  Saetro (05-11-2020),  TuaMan (05-11-2020),  vettor (05-13-2020)

  8. #5
    Registered Users
    Posts
    1,428
    Sex
    Omitted

    Quote Originally Posted by pmokeefe View Post
    Researchers then extracted DNA from these bones and the tooth and found that the mitochondrial sequences—the most abundant DNA in many fossils—were those of H. sapiens and related to those of people from Siberia, Spain, and China. The team is now analyzing the fossils’ nuclear DNA.
    Oldest Homo sapiens in Europe—and a cave bear pendant—suggest cultural link to Neanderthals
    This is some great news. I would love to see their relationship to Oase 1 and 2 and Kostenki 14. Also, this site would have taken a big hit from the Campanian eruption.

  9. The Following 4 Users Say Thank You to epoch For This Useful Post:

     Agamemnon (05-11-2020),  Helen (05-11-2020),  Milkyway (05-11-2020),  pmokeefe (05-11-2020)

  10. #6
    Registered Users
    Posts
    387
    Sex
    Location
    Paris
    Ethnicity
    French
    Nationality
    French
    Y-DNA (P)
    R1b-L21>A7309
    mtDNA (M)
    U6a7a1

    France European Union
    From supplemental information:
    The reconstructed mtDNAs of Bacho Kiro Cave specimens were aligned to 54 present-day
    humans, 12 ancient H. sapiens (SI Tab. 9), 22 Neanderthals, four Denisovans, one Sima de los
    Huesos individual and a chimpanzee to determine to which hominin group they belong. All of the
    six Bacho Kiro Cave mitochondrial genomes fall within the variation of H. sapiens. The
    haplogroups of the reconstructed mtDNAs were identified using HaploGrep87 and the Phylotree
    database (build 17). Bacho Kiro Cave molar (F6-620) and specimen AA7-738 carry the
    substitutions that define the M haplogroup with 0.98 posterior support (73G, 263G, 489C, 750G,
    1438G, 2706G, 4769G, 7028T, 8701G, 8860G, 9540C, 10398G, 10400T, 10873C, 11719A,
    12705T, 14766T, 14783C, 15043A, 15301A, 15326G, 16223T), along with two substitutions
    (4730T and 5315G) not seen in any present-day human population. The specimens BB7-240 and
    CC7-335 carry the substitutions characteristic of the N haplogroup (73G, 263G, 750G, 1438G,
    2706G, 4769G, 7028T, 8860G, 9456G, 11719A, 12705T, 14766T, 15326G, 16223T) with 0.93 and
    0.92 posterior support, respectively. Both of them share two mutations (4113A, 8155A) not
    detected in any present-day human population along with one specific mutation for each of them
    (194T in BB7-240 and 14790G in CC7-335) and fall basal to the other individuals of the
    macrohaplogroup N, with the smallest number of differences to Oase136. Specimen CC7-2289
    carries the substitutions defining the R haplogroup (73G, 263G, 750G, 1438G, 2706G, 4769G,
    7028T, 8860G, 11719A, 14766T, 15326G) with no private mutations and no additional
    substitutions that define sub-clades of haplogroup R, suggesting a relationship to the mtDNA
    ancestral to present-day haplogroup R. The mitochondrial genome of the specimen BK-1653
    belongs to haplogroup U8, commonly found in other Upper Palaeolithic humans in Europe29,110,
    and shows the smallest number of differences to the mtDNA genome of Kostenki 1473.

  11. The Following 7 Users Say Thank You to Bernard For This Useful Post:

     Agamemnon (05-11-2020),  epoch (05-11-2020),  etrusco (05-11-2020),  Onur Dincer (05-29-2020),  RCO (05-11-2020),  Ruderico (05-11-2020),  Saetro (05-11-2020)

  12. #7
    Registered Users
    Posts
    1,428
    Sex
    Omitted

    It's such a pity that only mtDNA was extracted from Fumane 2. I have seen an abstract for a lecture on a new way to extract DNA from a sample from Grotte du Renne, of similar age, but lost track of it. Too bad.

  13. #8
    Gold Class Member
    Posts
    787
    Sex
    Location
    San Diego, CA
    Ethnicity
    Polish/British Isles
    Nationality
    U.S.
    Y-DNA (P)
    R-A9185
    mtDNA (M)
    H1
    mtDNA (P)
    J1c2

    Poland England Ireland Munster
    My mistake.
    Last edited by pmokeefe; 05-11-2020 at 06:02 PM.
    YFull: YF14620 (Dante Labs 2018)

  14. #9
    Registered Users
    Posts
    1,164
    Sex
    Location
    Brazil
    Ethnicity
    Rio de Janeiro Colonial
    Nationality
    Brazilian
    Y-DNA (P)
    J1a1 FGC6064+ M365+
    mtDNA (M)
    H1ao1

    Suebi Kingdom Portugal 1143 Portugal 1485 Portugal Order of Christ Brazilian Empire Brazil
    Amazing revelations. So a population distantly related to Onge and Andamanese also reached Europe in the Palaeolithic.
    J1 FGC5987 to FGC6175 (188 new SNPs)
    MDKAs before Colonial Brazil
    Y-DNA - Milhazes, Barcelos, Minho, Portugal.
    mtDNA - Ilha Terceira, Azores, Portugal
    North_Swedish + PT + PT + PT @ 3.96 EUtest 4

  15. The Following 5 Users Say Thank You to RCO For This Useful Post:

     beyoku (05-20-2020),  etrusco (05-11-2020),  Nasser (02-10-2021),  parasar (05-12-2020),  pmokeefe (05-11-2020)

  16. #10
    Gold Class Member
    Posts
    787
    Sex
    Location
    San Diego, CA
    Ethnicity
    Polish/British Isles
    Nationality
    U.S.
    Y-DNA (P)
    R-A9185
    mtDNA (M)
    H1
    mtDNA (P)
    J1c2

    Poland England Ireland Munster
    Fig. 2: Maximum parsimony tree.
    From: Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria

    Maximum parsimony tree relating Bacho Kiro Cave mtDNAs to 54 present-day humans, 12 ancient H. sapiens, 22 Neanderthals, 4 Denisovans and 1 individual from Sima de los Huesos. The insert shows the part of the tree closest to the mtDNAs of the specimens from Bacho Kiro Cave. Bacho Kiro Cave mtDNAs are red. Asterisks denote mtDNA from ancient H. sapiens (Supplementary Table 9) other than the Bacho Kiro Cave specimens. The number of inferred substitutions per sequence is given above each branch. A chimpanzee mtDNA sequence was used to root the tree (not shown). rCRS, revised Cambridge Reference Sequence. U, R, N, M and L3 refer to the mitochondrial haplogroups.
    YFull: YF14620 (Dante Labs 2018)

  17. The Following 6 Users Say Thank You to pmokeefe For This Useful Post:

     etrusco (05-11-2020),  Lenny Nero (10-11-2020),  Onur Dincer (05-29-2020),  parasar (05-12-2020),  RCO (05-11-2020),  vettor (05-11-2020)

Page 1 of 44 12311 ... LastLast

Similar Threads

  1. Replies: 64
    Last Post: 11-11-2020, 01:15 PM
  2. Replies: 13
    Last Post: 07-21-2019, 03:34 PM
  3. Replies: 0
    Last Post: 02-02-2015, 06:17 AM
  4. Neanderthals did coexist with Homo Sapiens in Europe
    By Jean M in forum Human Evolution
    Replies: 4
    Last Post: 08-25-2014, 09:45 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •