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Thread: A Genomic Compendium of an Island: Documenting Continuity and Change across Irish Hum

  1. #11
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    Looks like Claristown14 (CT14) is A151, as it looks like we should expect for the descendants of Iar mac Dedad, including the Sil Conairi.
    Scandinavian-love structure

    recent and recently discovered Swedish, Danish and Norwegian (many 4th/5th cousins)
    recent East/North German
    Anglo-Saxon from recent rural English (Derbyshire/Staffordshire) with possible trace Danish
    1/16 Bronze Age Swedish from Finland/Karelia
    medieval Norwegian and Danish via Ireland (possibly surviving structure)
    other English and German (regions unknown)
    other NW to NE European

    closest modern Sweden2
    closest ancient Sigtuna vik84001

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  3. #12
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    Two things of interest re: the R1b1a1a2a1a2c1a1a remains:

    1) On the one hand, two of them lie firmly within the territory of the Connachta while the other lies within the territory of the southern O'Neill, which claim descent from the Connachta.

    2) On the other, the two from the West of Ireland (Mayo and Galway) look like they could belong to a line that migrated to Ireland from Britain. From page 189 in the report:

    The most likely candidate migrants from an archaeological perspective are two eastern individuals from Knowth (175-50 cal BC; 86-252 cal AD), whose burial rites are common in Britain and almost unknown in Ireland during the period (McGarry 2010). This interpretation is supported by their placement away from the main distributions of Irish Iron Age and modern variation. However, it must be noted that a number of other Irish Iron Age individuals place even further towards the British cluster, including three unrelated samples from Ballyglass Middle, the only Irish Iron Age site sampled that shows clear ancestral homogeneity among burials. The site itself is unusual in the relatively early date retrieved from unburnt bone (80-420 cal AD), at a time cremation was ubiquitous in Ireland. Two individuals from Derrynamanagh also show increased British affinities, but again the site shows wide differentiation on PCs 2 and 4, despite the close kinship among a number of samples (not included here). Previously undetected relatedness is also seen here between Derrynamanagh04 and Derrynamanagh05, later confirmed through IBD kinship analysis, which revealed the pair to be fourth degree relatives (Appendix II).
    The plot thickens!

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  5. #13
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    The homogenisation of British population structure through admixture
    In contrast to the gentle gradient of ancient Irish variation, British and continental individuals show a
    more punctuated distribution along PC2 (Fig. 4.6B-C), forming two clear clusters at both ends of modern
    British variation. Anglo-Saxons fall with southeastern English variation in this and all other PCs
    considered, alongside a Nordic Iron Age sample, reflecting the large genetic contribution of Germanic
    migrations to this part of the island (Leslie et al. 2015; Schiffels et al. 2016). Iron Age Britons comprise
    another tight grouping at the opposite end of British variation, emphasising the admixed nature of the
    modern population (Leslie et al. 2015; Martiniano et al. 2016; Schiffels et al. 2016). Early snapshots of
    continental introgression events may be represented by two samples that fall midway between the two
    groups, one from an Anglo-Saxon context (O3), which was reported as admixed in the original study
    (Schiffels et al. 2016), and the second from a Roman British population (6DT23)
    , another member of
    which was demonstrated to be of likely Middle Eastern origin (Martiniano et al. 2016). Notably, no Irish
    Iron Age samples are seen to fall into this region of the PC space.
    ^^So 6DRIF23 should NOT be thought of as an "Insular Celt" but as a blend of Continental Europe and Iron Age Briton following early (but not Bronze Age "early") introgression.

    Makes sense, given he's a DF19. But still perplexing since he's the oldest DF19 sample to date, and really hard to pin down.
    R1b>M269>L23>L51>L11>P312>DF19>DF88>FGC11833 >S4281>S4268>Z17112>BY44243

    Ancestors: Francis Cooke (M223/I2a2a) b1583; Hester Mahieu (Cooke) (J1c2 mtDNA) b.1584; Richard Warren (E-M35) b1578; Elizabeth Walker (Warren) (H1j mtDNA) b1583;
    John Mead (I2a1/P37.2) b1634; Rev. Joseph Hull (I1, L1301+ L1302-) b1595; Benjamin Harrington (M223/I2a2a-Y5729) b1618; Joshua Griffith (L21>DF13) b1593;
    John Wing (U106) b1584; Thomas Gunn (DF19) b1605; Hermann Wilhelm (DF19) b1635

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  7. #14
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    Still trying to get a handle on the SNPs and not sure I'm looking in the right place(s) or if I've missed something.

    So all the P312+ samples are either R1b1a1a2a1a2 (P312+ with no other terminal SNP) or R1b1a1a2a1a2c (on the road to L21)?
    R1b>M269>L23>L51>L11>P312>DF19>DF88>FGC11833 >S4281>S4268>Z17112>BY44243

    Ancestors: Francis Cooke (M223/I2a2a) b1583; Hester Mahieu (Cooke) (J1c2 mtDNA) b.1584; Richard Warren (E-M35) b1578; Elizabeth Walker (Warren) (H1j mtDNA) b1583;
    John Mead (I2a1/P37.2) b1634; Rev. Joseph Hull (I1, L1301+ L1302-) b1595; Benjamin Harrington (M223/I2a2a-Y5729) b1618; Joshua Griffith (L21>DF13) b1593;
    John Wing (U106) b1584; Thomas Gunn (DF19) b1605; Hermann Wilhelm (DF19) b1635

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  9. #15
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    Quote Originally Posted by Webb View Post
    it really is a well put together paper. 300 some pages of research. I'm disappointed that there are not any DF27 samples.
    Well, I am too. But if there had been any, I'd bet $5 to a stale donut that they'd have been missed (for DF27) because of the heterozygosity issue; or thrown out (for U152) because of the possible deamination issue. We discussed this, not long ago. https://anthrogenica.com/showthread....l=1#post635193

    If this problem gets raised enough times on enough forums, maybe by 2022 or so they will modify the academic protocols and start finding what they have (by design) been missing. Then in another five years the grad student papers will have been turned into dissertations, the embargoes on those lifted, and the Nature papers published. Then we'll see what else was around in 3000 BC, or whenever. Or, some of you who live that long will see.

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  11. #16
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    Quote Originally Posted by Nibelung View Post
    Looks like Claristown14 (CT14) is A151, as it looks like we should expect for the descendants of Iar mac Dedad, including the Sil Conairi.
    Daniel O'Connell's family belong to A151 and thus the Tara royal above should verify them as Corcu Duibne.
    Scandinavian-love structure

    recent and recently discovered Swedish, Danish and Norwegian (many 4th/5th cousins)
    recent East/North German
    Anglo-Saxon from recent rural English (Derbyshire/Staffordshire) with possible trace Danish
    1/16 Bronze Age Swedish from Finland/Karelia
    medieval Norwegian and Danish via Ireland (possibly surviving structure)
    other English and German (regions unknown)
    other NW to NE European

    closest modern Sweden2
    closest ancient Sigtuna vik84001

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  13. #17
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    Quote Originally Posted by David Mc View Post
    Are they actually M222? I find it hard to remember how to read the old long-form handles, but it looks like BM44 (from Ballyglass, Co. Mayo), DM09 (Derrynamanagh, Co. Galway), and LG14 (Lagore, Co. Meath) are all listed as R1b1a1a2a1a2c1a1a, which I thought was the equivalent of DF49.

    Either way, I'm ecstatic to see so many ancient DNA results coming out of Ireland in one paper. DIdn;t realize it was coming.
    Two of the Iron age ones are namely DM08 and DM09, if you look at the spreadsheet on Google docs they are both shown as M222+ and DF106-. Which is very interesting as DF106 (S658) makes up vast majority of all modern M222+ individuals (on order of 70-80%). It would be interesting to see how they would test for two other major M222 branches namely FGC4077 and S568. Given that they have 1x or so genomes from them it would also be interesting to see if they are negative for any of the SNP's in the 'M222 super block' eg. the 20+ snp's that all M222+ individuals test positive for (and thus are regarded as equivalents for M222)

    Also the early modern sample from Lagore Crannog site in Meath was also confirmed M222+/DF104+

    The Mayo (BM44) site appears to be DF23+ and negative for Z2961 and M222.
    (R1b-DF41+)
    (MtDNA: U4d3)

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  15. #18
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    Quote Originally Posted by Dubhthach View Post
    Two of the Iron age ones are namely DM08 and DM09, if you look at the spreadsheet on Google docs they are both shown as M222+ and DF106-. Which is very interesting as DF106 (S658) makes up vast majority of all modern M222+ individuals (on order of 70-80%). It would be interesting to see how they would test for two other major M222 branches namely FGC4077 and S568. Given that they have 1x or so genomes from them it would also be interesting to see if they are negative for any of the SNP's in the 'M222 super block' eg. the 20+ snp's that all M222+ individuals test positive for (and thus are regarded as equivalents for M222)

    Also the early modern sample from Lagore Crannog site in Meath was also confirmed M222+/DF104+

    The Mayo (BM44) site appears to be DF23+ and negative for Z2961 and M222.
    Thanks for clarifying that for me, Dubhthach! Very helpful.

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  17. #19
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    Quote Originally Posted by Webb View Post
    it really is a well put together paper. 300 some pages of research. I'm disappointed that there are not any DF27 samples.
    ancient DF27 sample I0806 from North Central Germany circa 2300 BC most closely matched present day Irish, so who knows, something may eventually turn up.

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    Quote Originally Posted by MitchellSince1893 View Post
    ancient DF27 sample I0806 from North Central Germany circa 2300 BC most closely matched present day Irish, so who knows, something may eventually turn up.
    I wouldn't trust K36 for this type of thing. Even K15 and K13 are dubious for ancient samples
    YDNA - E-Y31991>PF4428>Y134097>Y134104>Y168273>FT17866 Domingos Rodrigues, b. circa 1690 Hidden Content , Viana do Castelo, Portugal - Stonemason, miller.
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