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Thread: Genetic evolutionary differences in Italians: North vs South

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    Genetic evolutionary differences in Italians: North vs South

    Results
    We provided evidence for the early divergence of Italian groups dating back to the Late Glacial and for Neolithic and distinct Bronze Age migrations having further differentiated their gene pools. We inferred adaptive evolution at insulin-related loci in people from Italian regions with a temperate climate, while possible adaptations to pathogens and ultraviolet radiation were observed in Mediterranean Italians. Some of these adaptive events may also have secondarily modulated population disease or longevity predisposition.

    Conclusions
    We disentangled the contribution of multiple migratory and adaptive events in shaping the heterogeneous Italian genomic background, which exemplify population dynamics and gene-environment interactions that played significant roles also in the formation of the Continental and Southern European genomic landscapes.



    https://bmcbiol.biomedcentral.com/ar...0-00778-4#Abs1

  2. The Following 5 Users Say Thank You to Lancer For This Useful Post:

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