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Thread: Yseq’s new WGS400 WGS for $399

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  1. #1
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    Yseq’s new WGS400 WGS for $399

    Yseq has a new WGS test for $399 with 400 base long reads!

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    Very interesting. The stats they post seem better than what I got from my 30x Nebula WGS. I just can't find the number of reads they provide.

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    Quote Originally Posted by Robert McBride View Post
    Yseq has a new WGS test for $399 with 400 base long reads!
    One of the YSEQ Facebook Admins (Y. Alzanama) made an announcement a while back regarding this test, but it's nice to see it available now. The statistics mentioned on the product page look very promising (particularly the improved Y-STR clarity vs 150bp reads).

    Funnily enough, the Y-DNA Warehouse statistics page initially named this test something along the lines of DNBSEQ (YSEQ). I've downloaded a sample chrM BAM file from YSEQ's public FTP server and the read names clearly indicate that these are BGI DNBseq reads. The number of false mismatches per read are quite high but as these are random errors, they can be offset with sufficient coverage.
    Last edited by aaronbee2010; 02-16-2021 at 07:20 PM. Reason: Grammar
    YFull: YF72440 (FTDNA - IN41220)

    Ancestral Haplos (Punjabi Jatt):
    * Father: R2-M479 > M124 > V1180 > SK2142 > Y1379 > Y1383 > Y154920* (xZ6135) - M5a1a-G9064A (185G)
    * Maternal Uncle: R1b-M343 > M269 > Z2103 > Z2109 > Y14416 > Y35099 > Y84821 - U7a3a-A9852G > G6150A > C15433T
    * MGMs MGF: R1a-M420 > M198 > Z93 > L657 > Y7 - ?

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    Funnily enough, the Y-DNA Warehouse statistics page initially named this test something along the lines of DNBSEQ (YSEQ). I've downloaded a sample chrM BAM file from YSEQ's public FTP server and the read name clearly indicates that these are BGI DNBseq reads. The number of false mismatches per read are quite high but as these are random errors, they can be offset with sufficient coverage.[/QUOTE]

    Do you know if this type of test needs a lot of dna? With the previous yseq wgs you had to send them four sample brushes even if they already had your dna in storage .

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    Quote Originally Posted by Robert McBride View Post
    Do you know if this type of test needs a lot of dna? With the previous yseq wgs you had to send them four sample brushes even if they already had your dna in storage .
    Someone asked more or less the same question on the YSEQ Facebook group and T. Krahn answered them with this reply:

    We can use a standard YSEQ sample collection kit (2 brushes).
    YFull: YF72440 (FTDNA - IN41220)

    Ancestral Haplos (Punjabi Jatt):
    * Father: R2-M479 > M124 > V1180 > SK2142 > Y1379 > Y1383 > Y154920* (xZ6135) - M5a1a-G9064A (185G)
    * Maternal Uncle: R1b-M343 > M269 > Z2103 > Z2109 > Y14416 > Y35099 > Y84821 - U7a3a-A9852G > G6150A > C15433T
    * MGMs MGF: R1a-M420 > M198 > Z93 > L657 > Y7 - ?

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    Quote Originally Posted by Robert McBride View Post
    Do you know if this type of test needs a lot of dna? With the previous yseq wgs you had to send them four sample brushes even if they already had your dna in storage .
    According to a question on their Facebook page, Thomas replied:

    “We can use a standard YSEQ sample collection kit (2 brushes).”


    Edit:

    When asked if a customer could use a sample already stored at YSEQ, Thomas said:

    “Generally, yes. If the sample fails the QC for some reason, we’ll use the backup brush or in the worst case, contact you for a new sample”.
    Last edited by JMcB; 02-16-2021 at 07:30 PM.
    Paper Trail: 42.25% English, 31.25% Scottish, 12.5% Irish, 6.25% German, 6.25% Sicilian & 1.5% French. Or: 86% British Isles, 6.25% German, 6.25% Sicilian & 1.5% French.
    LDNA(c): 86.3% British Isles (48.6% English, 37.7% Scottish & Irish), 7.8% NW Germanic, 5.9% Europe South (Aegean 3.4%, Tuscany 1.3%, Sardinia 1.1%)
    BigY 700: I1-Z140 >I-F2642 >Y1966 >Y3649 >A13241 >Y3647 >A13248 (circa 620 AD) >A13242/YSEQ (circa 765 AD) >FT80854 (circa 1650 AD).

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    Quote Originally Posted by aaronbee2010 View Post
    One of the YSEQ Facebook Admins (Y. Alzanama) made an announcement a while back regarding this test, but it's nice to see it available now. The statistics mentioned on the product page look very promising (particularly the improved Y-STR clarity vs 150bp reads).

    Funnily enough, the Y-DNA Warehouse statistics page initially named this test something along the lines of DNBSEQ (YSEQ). I've downloaded a sample chrM BAM file from YSEQ's public FTP server and the read names clearly indicate that these are BGI DNBseq reads. The number of false mismatches per read are quite high but as these are random errors, they can be offset with sufficient coverage.
    According to your personal opinion, would it be worth it to buy this over Nebula, for the extra price? I am planning to get one for my dad, soon.
    Last edited by dosas; 02-17-2021 at 05:24 PM.

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    Even though this would be redundant for me, I’m tempted!
    Paper Trail: 42.25% English, 31.25% Scottish, 12.5% Irish, 6.25% German, 6.25% Sicilian & 1.5% French. Or: 86% British Isles, 6.25% German, 6.25% Sicilian & 1.5% French.
    LDNA(c): 86.3% British Isles (48.6% English, 37.7% Scottish & Irish), 7.8% NW Germanic, 5.9% Europe South (Aegean 3.4%, Tuscany 1.3%, Sardinia 1.1%)
    BigY 700: I1-Z140 >I-F2642 >Y1966 >Y3649 >A13241 >Y3647 >A13248 (circa 620 AD) >A13242/YSEQ (circa 765 AD) >FT80854 (circa 1650 AD).

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    My last three kits were all at 400bp, came in between Feb 4th and 7th. However I paid the full earlier price (e544.35) and now its cheaper!
    YSEQ:#37; YFull: YF01405 (Y Elite 2013)
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