Run of Homozygosity among Central/South Asians using David Pikes Homozygosity tool

[Kapisa]

Inspired by the following post by Zack, I utilized David Pike's Homozygosity tool to obtain:

1: Total ROH (measured in Mb(= Mbp) = mega base pairs = 1,000,000 bp

2: # of ROH segments more than length 200.

3: ROH % per chromosome (including individual SNPs aside from continuous ROH segments).

4: Total autosomal (chromosome 1-22) ROH %.

5: Large continuous ROH regions (more than 20Mb) per chromosome.

6: Estimated ROH % of the genome F(ROH).

Run of Homozygosity ROH stands for continuous regions within your genome where the "same haplotype is inherited from both parents."
For example, both stands of DNA carry the same base pair.

Furthermore, according to Zack, "the length of these homozygous regions, however, varies depending on the relation of your parents. If your parents are closely related (first cousins in my case), then you will have longer runs. If your parents are distantly related, then over the generations those genes have had a chance to recombine and so you will have shorter runs that are homozygous."

Here is the rest of the article: https://www.zackvision.com/weblog/2011/01/inbreeding/
Here is David Pike's Homozygosity tool:
https://www.math.mun.ca/~dapike/FF23utils/roh.php
Here is the program output for those interested in the following data; I have bold descriptions explaining output data.
Attachment 43420
===============
My numbers are as follows:
Note: I show results from only AncestryDNA kit since in my experience and as pointed out by Zack as well in comments, 23andme kits beyond V2 might be problematic. FTDNA is good.
In the settings u can select yes or no for No-Call SNPs treated as homozygous.
In my experience, default setting are fine. I only list results from default settings.

1: Total ROH=761.54Mb

2: # of ROH segments more than length 200= 77

3: ROH % per chromosome (including individual SNPs aside from continuous ROH segments)
Chr 1: 74.7
Chr 2: 74.52
Chr 3: 69.896
Chr 4: 76
Chr 5: 82.129
Chr 6: 78.575
Chr 7: 78.266
Chr 8: 71.967
Chr 9: 70.175
Chr 10: 76.581
Chr 11: 78.7
Chr 12: 72.819
Chr 13: 70.469
Chr 14: 76.121
Chr 15: 72.914
Chr 16: 74.486
Chr 17: 74.638
Chr 18: 77.002
Chr 19: 73.44
Chr 20: 76.322
Chr 21: 79.876
Chr 22: 72.967

(Note: Setting (No-call=Homozygous) has similar results with (No-Call=Heterozygous) in this case.)

4: Total autosomal (chromosome 1-22) ROH %age=75.137%

5: Large continuous ROH regions (more than 20Mb) per chromosome.

Chromosome 4: ROH of length 4519; DNA segment length 28.37 (Mb)
Chromosome 5: ROH of length 8509; DNA segment length 46.25 (Mb)
Chromosome 5: ROH of length 8640; DNA segment length 40.17 (Mb)
Chromosome 6: ROH of length 6746; DNA segment length 37.07 (Mb)
Chromosome 10: ROH of length 8105; DNA segment length 36.69 (Mb)
Chromosome 11: ROH of length 6011; DNA segment length 33.53 (Mb)
Chromosome 16: ROH of length 2337; DNA segment length 24.71 (Mb)
Chromosome 18: ROH of length 4992; DNA segment length 23.37 (Mb)

6: Estimated ROH% of the genome F(ROH)= 24.9%
calculated using total genome of 3058.1 Mb.

----
The number of ROH segments 77 as compared to the total length of ROH 761.54Mb, points to recent instances of endogamy within the family. As compared to the graph on Central/SouthAsians in the paper below, my results rughly compare to the highly endogamous groups such as Baloch. Individual results might not be the same as population averages and rough estimation is because the methods used in the paper are different.
https://journals.plos.org/plosone/ar...one.0013996#s2
Attachment 43418

Another paper linked below calculates some Rajput communities in Azad Kashmir and Jatt/Chaudhary's to have higher F(ROH). My FROH falls within that range. Usually, these results would be consistent with marriages among close kin.
https://www.biorxiv.org/content/bior...79190.full.pdf
Attachment 43419

High ROH counts are one indication of high number of recessive alleles (disease causing) among endogamous populations (true for my family). Thats one of the reasons I got interested in DNA testing.

======
Has anyone else used this tool? what were your results? Is it consistent with your family history?
Making quantitative assessments of endogamy is also an important part of conversion about population history in the Central South Asian region.

[Amber29]

mine:
I used my ancestry:

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr Y has a No-Call run of length 78 from position 2655180 to position 2911033 (255.85 Kb)
Chr Y has a No-Call run of length 126 from position 6630931 to position 7330975 (700.04 Kb)
Chr Y has a No-Call run of length 183 from position 7401585 to position 8852858 (1451.27 Kb)
Chr Y has a No-Call run of length 97 from position 9108252 to position 14407732 (5299.48 Kb)
Chr Y has a No-Call run of length 50 from position 14432928 to position 14814060 (381.13 Kb)
Chr Y has a No-Call run of length 90 from position 14814550 to position 15028176 (213.63 Kb)
Chr Y has a No-Call run of length 92 from position 15030650 to position 15585558 (554.91 Kb)
Chr Y has a No-Call run of length 155 from position 15587509 to position 16903692 (1316.18 Kb)
Chr Y has a No-Call run of length 338 from position 16904849 to position 21219443 (4314.59 Kb)
Chr Y has a No-Call run of length 117 from position 21225770 to position 21753199 (527.43 Kb)
Chr Y has a No-Call run of length 137 from position 21757306 to position 21983827 (226.52 Kb)
Chr Y has a No-Call run of length 215 from position 22003770 to position 23899533 (1895.76 Kb)
Chr Y has a No-Call run of length 30 from position 23959349 to position 58883690 (34924.34 Kb)

Chr 1 has a ROH of length 1989 from position 71036885 to position 82365041 (11.33 Mb)
Chr 2 has a ROH of length 208 from position 47635062 to position 47643464 ( 0.01 Mb)
Chr 2 has a ROH of length 642 from position 48018102 to position 48039744 ( 0.02 Mb)
Chr 2 has a ROH of length 359 from position 166821406 to position 166913475 ( 0.09 Mb)
Chr 2 has a ROH of length 1554 from position 179395221 to position 179648967 ( 0.25 Mb) (4 heterozygous SNPs treated as homozygous)
Chr 3 has a ROH of length 2269 from position 32839607 to position 39310269 ( 6.47 Mb)
Chr 3 has a ROH of length 288 from position 94209055 to position 97356400 ( 3.15 Mb)
Chr 5 has a ROH of length 324 from position 36886836 to position 37437274 ( 0.55 Mb)
Chr 5 has a ROH of length 665 from position 111984920 to position 112302830 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 2121 from position 471038 to position 6453352 ( 5.98 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 223 from position 32703162 to position 32798091 ( 0.09 Mb)
Chr 6 has a ROH of length 3136 from position 124922347 to position 139526049 (14.60 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 7 has a ROH of length 314 from position 117058220 to position 117347082 ( 0.29 Mb)
Chr 7 has a ROH of length 589 from position 153674630 to position 155225328 ( 1.55 Mb)
Chr 8 has a ROH of length 289 from position 107844447 to position 109595712 ( 1.75 Mb)
Chr 9 has a ROH of length 4605 from position 77411218 to position 97017858 (19.61 Mb)
Chr 10 has a ROH of length 248 from position 89595652 to position 89868930 ( 0.27 Mb)
Chr 11 has a ROH of length 589 from position 16843716 to position 18745177 ( 1.90 Mb)
Chr 11 has a ROH of length 287 from position 63164238 to position 64572560 ( 1.41 Mb)
Chr 11 has a ROH of length 214 from position 108170444 to position 108206694 ( 0.04 Mb)
Chr 11 has a ROH of length 201 from position 111346465 to position 112434430 ( 1.09 Mb)
Chr 12 has a ROH of length 206 from position 9351648 to position 10281255 ( 0.93 Mb)
Chr 12 has a ROH of length 208 from position 49374476 to position 49609808 ( 0.24 Mb)
Chr 13 has a ROH of length 1312 from position 32904299 to position 32915413 ( 0.01 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 13 has a ROH of length 276 from position 52426514 to position 53346606 ( 0.92 Mb)
Chr 14 has a ROH of length 253 from position 23856987 to position 23892881 ( 0.04 Mb)
Chr 15 has a ROH of length 265 from position 48694211 to position 48764862 ( 0.07 Mb)
Chr 16 has a ROH of length 393 from position 2087562 to position 2232121 ( 0.14 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 16 has a ROH of length 332 from position 23607079 to position 23653020 ( 0.05 Mb)
Chr 17 has a ROH of length 1855 from position 41173086 to position 41353410 ( 0.18 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 18 has a ROH of length 3727 from position 22513179 to position 41906424 (19.39 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 542 from position 11210916 to position 11233940 ( 0.02 Mb)
Chr 22 has a ROH of length 405 from position 49420129 to position 50349644 ( 0.93 Mb)
Chr X has a ROH of length 307 from position 38203687 to position 38505492 ( 0.30 Mb)
Chr X has a ROH of length 220 from position 79128154 to position 82236712 ( 3.11 Mb)
Chr X has a ROH of length 484 from position 100559427 to position 102998081 ( 2.44 Mb)
Chr X has a ROH of length 403 from position 107448639 to position 108407096 ( 0.96 Mb)
Chr X has a ROH of length 232 from position 154066677 to position 154916845 ( 0.85 Mb) (1 heterozygous SNPs treated as homozygous)
Chr Y has a ROH of length 1668 from position 5682834 to position 58883690 (53.20 Mb) (4 heterozygous SNPs treated as homozygous)
mtDNA has a ROH of length 224 from position 515 to position 16391 ( 0.02 Mb)
Total ROH Mb: 154.57
Total genome Mb: 3154.06
The detected ROHs account for 4.901 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 70.850 % (35034 of 49448 SNPs) are homozygous, 61 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 69.506 % (37192 of 53509 SNPs) are homozygous, 74 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr 3: 69.137 % (29321 of 42410 SNPs) are homozygous, 56 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 67.375 % (24571 of 36469 SNPs) are homozygous, 49 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 67.588 % (25760 of 38113 SNPs) are homozygous, 55 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 6: 73.852 % (31370 of 42477 SNPs) are homozygous, 74 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 7: 69.767 % (23690 of 33956 SNPs) are homozygous, 41 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 67.425 % (21975 of 32592 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 73.191 % (21300 of 29102 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 67.443 % (21718 of 32202 SNPs) are homozygous, 45 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 70.641 % (22490 of 31837 SNPs) are homozygous, 30 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 69.204 % (21220 of 30663 SNPs) are homozygous, 38 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 70.943 % (17291 of 24373 SNPs) are homozygous, 36 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 14: 69.076 % (14345 of 20767 SNPs) are homozygous, 24 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 68.984 % (14399 of 20873 SNPs) are homozygous, 21 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 69.383 % (15818 of 22798 SNPs) are homozygous, 26 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 17: 73.154 % (16216 of 22167 SNPs) are homozygous, 19 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 18: 74.027 % (13863 of 18727 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 19: 70.897 % (11630 of 16404 SNPs) are homozygous, 27 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 66.849 % (11853 of 17731 SNPs) are homozygous, 16 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 66.640 % ( 6692 of 10042 SNPs) are homozygous, 11 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 68.609 % ( 7416 of 10809 SNPs) are homozygous, 5 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 75.638 % (18824 of 24887 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr Y: 1803 SNPs, 1735 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr XY: 46 SNPs, 0 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 224 SNPs, 1 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 0.126 % ( 803 of 637469 SNPs) are NoCalls
Total autosomal (Chr 1-22): 30.167 % (192305 of 637469 SNPs) are Heterozygous (this tally excludes 12 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 69.833 % (445164 of 637469 SNPs) are Homozygous (this tally includes 12 heterozygous SNPs that were treated as homozygous)


23andme v5

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr 9 has a No-Call run of length 10 from position 44766443 to position 44805175 (38.73 Kb)
Chr 21 has a No-Call run of length 12 from position 10748558 to position 10849946 (101.39 Kb)
Chr Y has a No-Call run of length 3733 from position 1726773 to position 58997092 (57270.32 Kb)

Chr 1 has a ROH of length 2083 from position 71020447 to position 82342336 (11.32 Mb)
Chr 1 has a ROH of length 228 from position 121355922 to position 144896319 (23.54 Mb)
Chr 1 has a ROH of length 224 from position 235062181 to position 236141259 ( 1.08 Mb)
Chr 2 has a ROH of length 391 from position 166606326 to position 166930062 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 2 has a ROH of length 219 from position 179364778 to position 179486037 ( 0.12 Mb)
Chr 3 has a ROH of length 1578 from position 32777275 to position 39313391 ( 6.54 Mb)
Chr 3 has a ROH of length 397 from position 94182127 to position 97398548 ( 3.22 Mb)
Chr 3 has a ROH of length 212 from position 168593055 to position 169084827 ( 0.49 Mb)
Chr 5 has a ROH of length 262 from position 36833115 to position 37582130 ( 0.75 Mb)
Chr 6 has a ROH of length 1758 from position 466907 to position 6453352 ( 5.99 Mb)
Chr 6 has a ROH of length 211 from position 32713188 to position 32797876 ( 0.08 Mb)
Chr 6 has a ROH of length 3156 from position 124915655 to position 139529521 (14.61 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 213 from position 140163298 to position 142027189 ( 1.86 Mb)
Chr 7 has a ROH of length 493 from position 153794933 to position 155225924 ( 1.43 Mb)
Chr 8 has a ROH of length 326 from position 107913227 to position 109601964 ( 1.69 Mb)
Chr 9 has a ROH of length 4345 from position 77398791 to position 97062295 (19.66 Mb)
Chr 10 has a ROH of length 209 from position 64205248 to position 65310986 ( 1.11 Mb)
Chr 11 has a ROH of length 549 from position 16843716 to position 18746427 ( 1.90 Mb)
Chr 11 has a ROH of length 338 from position 63171313 to position 64590854 ( 1.42 Mb)
Chr 12 has a ROH of length 224 from position 9318694 to position 10321383 ( 1.00 Mb)
Chr 12 has a ROH of length 208 from position 56076266 to position 56878301 ( 0.80 Mb)
Chr 13 has a ROH of length 542 from position 32890583 to position 32919384 ( 0.03 Mb)
Chr 13 has a ROH of length 211 from position 32944547 to position 33175434 ( 0.23 Mb)
Chr 14 has a ROH of length 205 from position 23840033 to position 23902297 ( 0.06 Mb)
Chr 16 has a ROH of length 206 from position 32581849 to position 46538405 (13.96 Mb)
Chr 17 has a ROH of length 600 from position 41143775 to position 41448680 ( 0.30 Mb)
Chr 18 has a ROH of length 3576 from position 22517480 to position 41967979 (19.45 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 228 from position 11210898 to position 11234021 ( 0.02 Mb)
Chr 22 has a ROH of length 386 from position 49417110 to position 50417824 ( 1.00 Mb)
Chr X has a ROH of length 223 from position 100559427 to position 103359175 ( 2.80 Mb)
Chr Y has a ROH of length 3733 from position 1726773 to position 58997092 (57.27 Mb)
Total ROH Mb: 194.07
Total genome Mb: 3007.10
The detected ROHs account for 6.454 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 84.478 % (41825 of 49510 SNPs) are homozygous, 1200 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 83.537 % (43248 of 51771 SNPs) are homozygous, 1046 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 3: 83.876 % (36086 of 43023 SNPs) are homozygous, 941 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 83.143 % (32819 of 39473 SNPs) are homozygous, 878 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 83.494 % (30916 of 37028 SNPs) are homozygous, 790 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 6: 84.548 % (37219 of 44021 SNPs) are homozygous, 876 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 7: 84.014 % (28864 of 34356 SNPs) are homozygous, 849 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 82.870 % (26254 of 31681 SNPs) are homozygous, 620 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 85.400 % (22584 of 26445 SNPs) are homozygous, 682 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 82.570 % (25202 of 30522 SNPs) are homozygous, 651 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 83.870 % (25952 of 30943 SNPs) are homozygous, 604 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 82.944 % (24412 of 29432 SNPs) are homozygous, 661 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 83.293 % (18391 of 22080 SNPs) are homozygous, 368 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 14: 82.852 % (16538 of 19961 SNPs) are homozygous, 462 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 83.016 % (15778 of 19006 SNPs) are homozygous, 421 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 82.810 % (16890 of 20396 SNPs) are homozygous, 489 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 17: 84.099 % (16316 of 19401 SNPs) are homozygous, 504 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 18: 85.917 % (15185 of 17674 SNPs) are homozygous, 284 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 19: 82.371 % (12256 of 14879 SNPs) are homozygous, 561 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 81.165 % (11997 of 14781 SNPs) are homozygous, 298 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 82.061 % ( 7063 of 8607 SNPs) are homozygous, 221 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 84.083 % ( 7496 of 8915 SNPs) are homozygous, 271 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 76.509 % (12647 of 16530 SNPs) are homozygous, 544 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr Y: 3733 SNPs, 3733 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 4305 SNPs, 323 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 2.228 % ( 13677 of 613905 SNPs) are NoCalls
Total autosomal (Chr 1-22): 16.389 % (100614 of 613905 SNPs) are Heterozygous (this tally excludes 4 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 83.611 % (513291 of 613905 SNPs) are Homozygous (this tally includes 4 heterozygous SNPs that were treated as homozygous)

[maroco]

mine:
I used my ancestry:

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr Y has a No-Call run of length 78 from position 2655180 to position 2911033 (255.85 Kb)
Chr Y has a No-Call run of length 126 from position 6630931 to position 7330975 (700.04 Kb)
Chr Y has a No-Call run of length 183 from position 7401585 to position 8852858 (1451.27 Kb)
Chr Y has a No-Call run of length 97 from position 9108252 to position 14407732 (5299.48 Kb)
Chr Y has a No-Call run of length 50 from position 14432928 to position 14814060 (381.13 Kb)
Chr Y has a No-Call run of length 90 from position 14814550 to position 15028176 (213.63 Kb)
Chr Y has a No-Call run of length 92 from position 15030650 to position 15585558 (554.91 Kb)
Chr Y has a No-Call run of length 155 from position 15587509 to position 16903692 (1316.18 Kb)
Chr Y has a No-Call run of length 338 from position 16904849 to position 21219443 (4314.59 Kb)
Chr Y has a No-Call run of length 117 from position 21225770 to position 21753199 (527.43 Kb)
Chr Y has a No-Call run of length 137 from position 21757306 to position 21983827 (226.52 Kb)
Chr Y has a No-Call run of length 215 from position 22003770 to position 23899533 (1895.76 Kb)
Chr Y has a No-Call run of length 30 from position 23959349 to position 58883690 (34924.34 Kb)

Chr 1 has a ROH of length 1989 from position 71036885 to position 82365041 (11.33 Mb)
Chr 2 has a ROH of length 208 from position 47635062 to position 47643464 ( 0.01 Mb)
Chr 2 has a ROH of length 642 from position 48018102 to position 48039744 ( 0.02 Mb)
Chr 2 has a ROH of length 359 from position 166821406 to position 166913475 ( 0.09 Mb)
Chr 2 has a ROH of length 1554 from position 179395221 to position 179648967 ( 0.25 Mb) (4 heterozygous SNPs treated as homozygous)
Chr 3 has a ROH of length 2269 from position 32839607 to position 39310269 ( 6.47 Mb)
Chr 3 has a ROH of length 288 from position 94209055 to position 97356400 ( 3.15 Mb)
Chr 5 has a ROH of length 324 from position 36886836 to position 37437274 ( 0.55 Mb)
Chr 5 has a ROH of length 665 from position 111984920 to position 112302830 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 2121 from position 471038 to position 6453352 ( 5.98 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 223 from position 32703162 to position 32798091 ( 0.09 Mb)
Chr 6 has a ROH of length 3136 from position 124922347 to position 139526049 (14.60 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 7 has a ROH of length 314 from position 117058220 to position 117347082 ( 0.29 Mb)
Chr 7 has a ROH of length 589 from position 153674630 to position 155225328 ( 1.55 Mb)
Chr 8 has a ROH of length 289 from position 107844447 to position 109595712 ( 1.75 Mb)
Chr 9 has a ROH of length 4605 from position 77411218 to position 97017858 (19.61 Mb)
Chr 10 has a ROH of length 248 from position 89595652 to position 89868930 ( 0.27 Mb)
Chr 11 has a ROH of length 589 from position 16843716 to position 18745177 ( 1.90 Mb)
Chr 11 has a ROH of length 287 from position 63164238 to position 64572560 ( 1.41 Mb)
Chr 11 has a ROH of length 214 from position 108170444 to position 108206694 ( 0.04 Mb)
Chr 11 has a ROH of length 201 from position 111346465 to position 112434430 ( 1.09 Mb)
Chr 12 has a ROH of length 206 from position 9351648 to position 10281255 ( 0.93 Mb)
Chr 12 has a ROH of length 208 from position 49374476 to position 49609808 ( 0.24 Mb)
Chr 13 has a ROH of length 1312 from position 32904299 to position 32915413 ( 0.01 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 13 has a ROH of length 276 from position 52426514 to position 53346606 ( 0.92 Mb)
Chr 14 has a ROH of length 253 from position 23856987 to position 23892881 ( 0.04 Mb)
Chr 15 has a ROH of length 265 from position 48694211 to position 48764862 ( 0.07 Mb)
Chr 16 has a ROH of length 393 from position 2087562 to position 2232121 ( 0.14 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 16 has a ROH of length 332 from position 23607079 to position 23653020 ( 0.05 Mb)
Chr 17 has a ROH of length 1855 from position 41173086 to position 41353410 ( 0.18 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 18 has a ROH of length 3727 from position 22513179 to position 41906424 (19.39 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 542 from position 11210916 to position 11233940 ( 0.02 Mb)
Chr 22 has a ROH of length 405 from position 49420129 to position 50349644 ( 0.93 Mb)
Chr X has a ROH of length 307 from position 38203687 to position 38505492 ( 0.30 Mb)
Chr X has a ROH of length 220 from position 79128154 to position 82236712 ( 3.11 Mb)
Chr X has a ROH of length 484 from position 100559427 to position 102998081 ( 2.44 Mb)
Chr X has a ROH of length 403 from position 107448639 to position 108407096 ( 0.96 Mb)
Chr X has a ROH of length 232 from position 154066677 to position 154916845 ( 0.85 Mb) (1 heterozygous SNPs treated as homozygous)
Chr Y has a ROH of length 1668 from position 5682834 to position 58883690 (53.20 Mb) (4 heterozygous SNPs treated as homozygous)
mtDNA has a ROH of length 224 from position 515 to position 16391 ( 0.02 Mb)
Total ROH Mb: 154.57
Total genome Mb: 3154.06
The detected ROHs account for 4.901 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 70.850 % (35034 of 49448 SNPs) are homozygous, 61 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 69.506 % (37192 of 53509 SNPs) are homozygous, 74 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr 3: 69.137 % (29321 of 42410 SNPs) are homozygous, 56 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 67.375 % (24571 of 36469 SNPs) are homozygous, 49 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 67.588 % (25760 of 38113 SNPs) are homozygous, 55 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 6: 73.852 % (31370 of 42477 SNPs) are homozygous, 74 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 7: 69.767 % (23690 of 33956 SNPs) are homozygous, 41 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 67.425 % (21975 of 32592 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 73.191 % (21300 of 29102 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 67.443 % (21718 of 32202 SNPs) are homozygous, 45 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 70.641 % (22490 of 31837 SNPs) are homozygous, 30 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 69.204 % (21220 of 30663 SNPs) are homozygous, 38 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 70.943 % (17291 of 24373 SNPs) are homozygous, 36 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 14: 69.076 % (14345 of 20767 SNPs) are homozygous, 24 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 68.984 % (14399 of 20873 SNPs) are homozygous, 21 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 69.383 % (15818 of 22798 SNPs) are homozygous, 26 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 17: 73.154 % (16216 of 22167 SNPs) are homozygous, 19 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 18: 74.027 % (13863 of 18727 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 19: 70.897 % (11630 of 16404 SNPs) are homozygous, 27 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 66.849 % (11853 of 17731 SNPs) are homozygous, 16 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 66.640 % ( 6692 of 10042 SNPs) are homozygous, 11 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 68.609 % ( 7416 of 10809 SNPs) are homozygous, 5 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 75.638 % (18824 of 24887 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr Y: 1803 SNPs, 1735 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr XY: 46 SNPs, 0 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 224 SNPs, 1 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 0.126 % ( 803 of 637469 SNPs) are NoCalls
Total autosomal (Chr 1-22): 30.167 % (192305 of 637469 SNPs) are Heterozygous (this tally excludes 12 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 69.833 % (445164 of 637469 SNPs) are Homozygous (this tally includes 12 heterozygous SNPs that were treated as homozygous)


23andme v5

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr 9 has a No-Call run of length 10 from position 44766443 to position 44805175 (38.73 Kb)
Chr 21 has a No-Call run of length 12 from position 10748558 to position 10849946 (101.39 Kb)
Chr Y has a No-Call run of length 3733 from position 1726773 to position 58997092 (57270.32 Kb)

Chr 1 has a ROH of length 2083 from position 71020447 to position 82342336 (11.32 Mb)
Chr 1 has a ROH of length 228 from position 121355922 to position 144896319 (23.54 Mb)
Chr 1 has a ROH of length 224 from position 235062181 to position 236141259 ( 1.08 Mb)
Chr 2 has a ROH of length 391 from position 166606326 to position 166930062 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 2 has a ROH of length 219 from position 179364778 to position 179486037 ( 0.12 Mb)
Chr 3 has a ROH of length 1578 from position 32777275 to position 39313391 ( 6.54 Mb)
Chr 3 has a ROH of length 397 from position 94182127 to position 97398548 ( 3.22 Mb)
Chr 3 has a ROH of length 212 from position 168593055 to position 169084827 ( 0.49 Mb)
Chr 5 has a ROH of length 262 from position 36833115 to position 37582130 ( 0.75 Mb)
Chr 6 has a ROH of length 1758 from position 466907 to position 6453352 ( 5.99 Mb)
Chr 6 has a ROH of length 211 from position 32713188 to position 32797876 ( 0.08 Mb)
Chr 6 has a ROH of length 3156 from position 124915655 to position 139529521 (14.61 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 213 from position 140163298 to position 142027189 ( 1.86 Mb)
Chr 7 has a ROH of length 493 from position 153794933 to position 155225924 ( 1.43 Mb)
Chr 8 has a ROH of length 326 from position 107913227 to position 109601964 ( 1.69 Mb)
Chr 9 has a ROH of length 4345 from position 77398791 to position 97062295 (19.66 Mb)
Chr 10 has a ROH of length 209 from position 64205248 to position 65310986 ( 1.11 Mb)
Chr 11 has a ROH of length 549 from position 16843716 to position 18746427 ( 1.90 Mb)
Chr 11 has a ROH of length 338 from position 63171313 to position 64590854 ( 1.42 Mb)
Chr 12 has a ROH of length 224 from position 9318694 to position 10321383 ( 1.00 Mb)
Chr 12 has a ROH of length 208 from position 56076266 to position 56878301 ( 0.80 Mb)
Chr 13 has a ROH of length 542 from position 32890583 to position 32919384 ( 0.03 Mb)
Chr 13 has a ROH of length 211 from position 32944547 to position 33175434 ( 0.23 Mb)
Chr 14 has a ROH of length 205 from position 23840033 to position 23902297 ( 0.06 Mb)
Chr 16 has a ROH of length 206 from position 32581849 to position 46538405 (13.96 Mb)
Chr 17 has a ROH of length 600 from position 41143775 to position 41448680 ( 0.30 Mb)
Chr 18 has a ROH of length 3576 from position 22517480 to position 41967979 (19.45 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 228 from position 11210898 to position 11234021 ( 0.02 Mb)
Chr 22 has a ROH of length 386 from position 49417110 to position 50417824 ( 1.00 Mb)
Chr X has a ROH of length 223 from position 100559427 to position 103359175 ( 2.80 Mb)
Chr Y has a ROH of length 3733 from position 1726773 to position 58997092 (57.27 Mb)
Total ROH Mb: 194.07
Total genome Mb: 3007.10
The detected ROHs account for 6.454 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 84.478 % (41825 of 49510 SNPs) are homozygous, 1200 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 83.537 % (43248 of 51771 SNPs) are homozygous, 1046 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 3: 83.876 % (36086 of 43023 SNPs) are homozygous, 941 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 83.143 % (32819 of 39473 SNPs) are homozygous, 878 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 83.494 % (30916 of 37028 SNPs) are homozygous, 790 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 6: 84.548 % (37219 of 44021 SNPs) are homozygous, 876 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 7: 84.014 % (28864 of 34356 SNPs) are homozygous, 849 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 82.870 % (26254 of 31681 SNPs) are homozygous, 620 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 85.400 % (22584 of 26445 SNPs) are homozygous, 682 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 82.570 % (25202 of 30522 SNPs) are homozygous, 651 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 83.870 % (25952 of 30943 SNPs) are homozygous, 604 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 82.944 % (24412 of 29432 SNPs) are homozygous, 661 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 83.293 % (18391 of 22080 SNPs) are homozygous, 368 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 14: 82.852 % (16538 of 19961 SNPs) are homozygous, 462 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 83.016 % (15778 of 19006 SNPs) are homozygous, 421 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 82.810 % (16890 of 20396 SNPs) are homozygous, 489 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 17: 84.099 % (16316 of 19401 SNPs) are homozygous, 504 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 18: 85.917 % (15185 of 17674 SNPs) are homozygous, 284 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 19: 82.371 % (12256 of 14879 SNPs) are homozygous, 561 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 81.165 % (11997 of 14781 SNPs) are homozygous, 298 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 82.061 % ( 7063 of 8607 SNPs) are homozygous, 221 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 84.083 % ( 7496 of 8915 SNPs) are homozygous, 271 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 76.509 % (12647 of 16530 SNPs) are homozygous, 544 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr Y: 3733 SNPs, 3733 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 4305 SNPs, 323 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 2.228 % ( 13677 of 613905 SNPs) are NoCalls
Total autosomal (Chr 1-22): 16.389 % (100614 of 613905 SNPs) are Heterozygous (this tally excludes 4 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 83.611 % (513291 of 613905 SNPs) are Homozygous (this tally includes 4 heterozygous SNPs that were treated as homozygous)

You’re gonna have to teach me this lol

[subzero85]

23andMe v3 data.

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr Y has a No-Call run of length 21 from position 2897433 to position 3004873 (107.44 Kb)
Chr Y has a No-Call run of length 45 from position 3011019 to position 3262129 (251.11 Kb)
Chr Y has a No-Call run of length 16 from position 3310270 to position 3401707 (91.44 Kb)
Chr Y has a No-Call run of length 25 from position 3436718 to position 3480985 (44.27 Kb)
Chr Y has a No-Call run of length 17 from position 3547060 to position 3627909 (80.85 Kb)
Chr Y has a No-Call run of length 17 from position 3640050 to position 3682867 (42.82 Kb)
Chr Y has a No-Call run of length 11 from position 3697126 to position 3711649 (14.52 Kb)
Chr Y has a No-Call run of length 11 from position 3721230 to position 3764211 (42.98 Kb)
Chr Y has a No-Call run of length 34 from position 3790709 to position 4017487 (226.78 Kb)
Chr Y has a No-Call run of length 34 from position 4084431 to position 4239428 (155.00 Kb)
Chr Y has a No-Call run of length 64 from position 4262761 to position 4527871 (265.11 Kb)
Chr Y has a No-Call run of length 44 from position 4559101 to position 4723799 (164.70 Kb)
Chr Y has a No-Call run of length 18 from position 4749584 to position 4800467 (50.88 Kb)
Chr Y has a No-Call run of length 38 from position 4804521 to position 4871809 (67.29 Kb)
Chr Y has a No-Call run of length 24 from position 4882982 to position 4925084 (42.10 Kb)
Chr Y has a No-Call run of length 18 from position 4927998 to position 4939145 (11.15 Kb)
Chr Y has a No-Call run of length 41 from position 4957608 to position 5012099 (54.49 Kb)
Chr Y has a No-Call run of length 46 from position 5060885 to position 5187330 (126.44 Kb)
Chr Y has a No-Call run of length 39 from position 5191781 to position 5292479 (100.70 Kb)
Chr Y has a No-Call run of length 42 from position 5298470 to position 5366585 (68.11 Kb)
Chr Y has a No-Call run of length 85 from position 5385063 to position 5574967 (189.90 Kb)
Chr Y has a No-Call run of length 49 from position 5577743 to position 5754102 (176.36 Kb)
Chr Y has a No-Call run of length 29 from position 5755943 to position 5908658 (152.72 Kb)
Chr Y has a No-Call run of length 14 from position 5949606 to position 6006768 (57.16 Kb)
Chr Y has a No-Call run of length 12 from position 6082930 to position 6449519 (366.59 Kb)
Chr Y has a No-Call run of length 25 from position 6455097 to position 6736154 (281.06 Kb)

Chr 1 has a ROH of length 211 from position 215130169 to position 215899617 ( 0.77 Mb)
Chr 3 has a ROH of length 290 from position 37045903 to position 37125699 ( 0.08 Mb)
Chr 3 has a ROH of length 305 from position 49877585 to position 51755441 ( 1.88 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 3 has a ROH of length 204 from position 88992369 to position 90428286 ( 1.44 Mb)
Chr 3 has a ROH of length 237 from position 107650668 to position 108454021 ( 0.80 Mb)
Chr 3 has a ROH of length 256 from position 153553043 to position 154715596 ( 1.16 Mb)
Chr 3 has a ROH of length 274 from position 155409181 to position 156339632 ( 0.93 Mb)
Chr 3 has a ROH of length 259 from position 165435695 to position 166533427 ( 1.10 Mb)
Chr 4 has a ROH of length 206 from position 79002597 to position 79494430 ( 0.49 Mb)
Chr 4 has a ROH of length 231 from position 99988567 to position 100243952 ( 0.26 Mb)
Chr 6 has a ROH of length 333 from position 17755963 to position 18602913 ( 0.85 Mb)
Chr 7 has a ROH of length 334 from position 5292732 to position 6372038 ( 1.08 Mb)
Chr 7 has a ROH of length 200 from position 21015297 to position 21350308 ( 0.34 Mb)
Chr 7 has a ROH of length 304 from position 98804967 to position 99489005 ( 0.68 Mb)
Chr 7 has a ROH of length 252 from position 116709570 to position 117238445 ( 0.53 Mb)
Chr 8 has a ROH of length 228 from position 119164828 to position 119698024 ( 0.53 Mb)
Chr 9 has a ROH of length 2693 from position 13507764 to position 18769219 ( 5.26 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 9 has a ROH of length 238 from position 28755357 to position 29440074 ( 0.68 Mb)
Chr 10 has a ROH of length 573 from position 93333956 to position 95091023 ( 1.76 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 10 has a ROH of length 417 from position 96469669 to position 97009657 ( 0.54 Mb)
Chr 11 has a ROH of length 234 from position 56247631 to position 56975099 ( 0.73 Mb)
Chr 12 has a ROH of length 276 from position 42736267 to position 43415429 ( 0.68 Mb)
Chr 13 has a ROH of length 410 from position 69212346 to position 70171358 ( 0.96 Mb)
Chr 14 has a ROH of length 249 from position 95015544 to position 95342453 ( 0.33 Mb)
Chr 15 has a ROH of length 242 from position 76103430 to position 77381222 ( 1.28 Mb)
Chr 16 has a ROH of length 542 from position 2087562 to position 2229887 ( 0.14 Mb)
Chr 16 has a ROH of length 223 from position 35213863 to position 48220951 (13.01 Mb)
Chr 16 has a ROH of length 206 from position 77320605 to position 77608741 ( 0.29 Mb)
Chr 17 has a ROH of length 381 from position 48262775 to position 48309874 ( 0.05 Mb)
Chr 17 has a ROH of length 210 from position 58154207 to position 59374867 ( 1.22 Mb)
Chr 18 has a ROH of length 227 from position 24447786 to position 24626796 ( 0.18 Mb)
Chr 18 has a ROH of length 363 from position 34027096 to position 35023785 ( 1.00 Mb)
Chr 21 has a ROH of length 212 from position 21210548 to position 21775361 ( 0.56 Mb)
Chr 22 has a ROH of length 261 from position 42218856 to position 42688724 ( 0.47 Mb)
Total ROH Mb: 42.04
Total genome Mb: 3003.48
The detected ROHs account for 1.400 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 71.058 % (54725 of 77015 SNPs) are homozygous, 387 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 70.273 % (54410 of 77427 SNPs) are homozygous, 376 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 3: 69.796 % (44202 of 63330 SNPs) are homozygous, 270 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 4: 68.735 % (37838 of 55049 SNPs) are homozygous, 261 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 69.105 % (38732 of 56048 SNPs) are homozygous, 254 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 6: 70.768 % (44774 of 63269 SNPs) are homozygous, 344 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 7: 70.264 % (35857 of 51032 SNPs) are homozygous, 287 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 68.660 % (33804 of 49234 SNPs) are homozygous, 239 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 71.244 % (30622 of 42982 SNPs) are homozygous, 254 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 10: 70.552 % (35523 of 50350 SNPs) are homozygous, 246 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 11: 69.703 % (33449 of 47988 SNPs) are homozygous, 242 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 69.520 % (32798 of 47178 SNPs) are homozygous, 228 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 70.514 % (25464 of 36112 SNPs) are homozygous, 156 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 14: 69.456 % (21434 of 30860 SNPs) are homozygous, 130 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 70.463 % (20025 of 28419 SNPs) are homozygous, 124 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 70.280 % (21216 of 30188 SNPs) are homozygous, 160 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 17: 70.643 % (18911 of 26770 SNPs) are homozygous, 146 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 18: 68.819 % (19255 of 27979 SNPs) are homozygous, 130 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 19: 71.734 % (13336 of 18591 SNPs) are homozygous, 122 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 70.204 % (16743 of 23849 SNPs) are homozygous, 109 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 67.740 % ( 9086 of 13413 SNPs) are homozygous, 64 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 71.341 % (10074 of 14121 SNPs) are homozygous, 79 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 2.957 % ( 769 of 26008 SNPs) are homozygous, 442 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr Y: 1906 SNPs, 1004 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 3930 SNPs, 63 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 0.495 % ( 4608 of 931204 SNPs) are NoCalls
Total autosomal (Chr 1-22): 29.953 % (278926 of 931204 SNPs) are Heterozygous (this tally excludes 3 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 70.047 % (652278 of 931204 SNPs) are Homozygous (this tally includes 3 heterozygous SNPs that were treated as homozygous)
Processing Completed.

[subzero85]

mine:
I used my ancestry:
Total autosomal (Chr 1-22): 69.833 % (445164 of 637469 SNPs) are Homozygous (this tally includes 12 heterozygous SNPs that were treated as homozygous)

23andme v5
Total autosomal (Chr 1-22): 83.611 % (513291 of 613905 SNPs) are Homozygous (this tally includes 4 heterozygous SNPs that were treated as homozygous)

Maybe I'm reading this wrong, but this seems like a vast difference?

[Amber29]

You’re gonna have to teach me this lol

he posted a tool at the top but i wonder what it means xD lol

[subzero85]

he posted a tool at the top but i wonder what it means xD lol

It's a measure of how inbred you are AND/OR how endogamous your ancestors were.

[Amber29]

Maybe I'm reading this wrong, but this seems like a vast difference?

yes it is thats why kapisa said - the files of 23andme after v2 will be problematic from the source he mentioned etc.

[Kapisa]

mine:
I used my ancestry:

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr Y has a No-Call run of length 78 from position 2655180 to position 2911033 (255.85 Kb)
Chr Y has a No-Call run of length 126 from position 6630931 to position 7330975 (700.04 Kb)
Chr Y has a No-Call run of length 183 from position 7401585 to position 8852858 (1451.27 Kb)
Chr Y has a No-Call run of length 97 from position 9108252 to position 14407732 (5299.48 Kb)
Chr Y has a No-Call run of length 50 from position 14432928 to position 14814060 (381.13 Kb)
Chr Y has a No-Call run of length 90 from position 14814550 to position 15028176 (213.63 Kb)
Chr Y has a No-Call run of length 92 from position 15030650 to position 15585558 (554.91 Kb)
Chr Y has a No-Call run of length 155 from position 15587509 to position 16903692 (1316.18 Kb)
Chr Y has a No-Call run of length 338 from position 16904849 to position 21219443 (4314.59 Kb)
Chr Y has a No-Call run of length 117 from position 21225770 to position 21753199 (527.43 Kb)
Chr Y has a No-Call run of length 137 from position 21757306 to position 21983827 (226.52 Kb)
Chr Y has a No-Call run of length 215 from position 22003770 to position 23899533 (1895.76 Kb)
Chr Y has a No-Call run of length 30 from position 23959349 to position 58883690 (34924.34 Kb)

Chr 1 has a ROH of length 1989 from position 71036885 to position 82365041 (11.33 Mb)
Chr 2 has a ROH of length 208 from position 47635062 to position 47643464 ( 0.01 Mb)
Chr 2 has a ROH of length 642 from position 48018102 to position 48039744 ( 0.02 Mb)
Chr 2 has a ROH of length 359 from position 166821406 to position 166913475 ( 0.09 Mb)
Chr 2 has a ROH of length 1554 from position 179395221 to position 179648967 ( 0.25 Mb) (4 heterozygous SNPs treated as homozygous)
Chr 3 has a ROH of length 2269 from position 32839607 to position 39310269 ( 6.47 Mb)
Chr 3 has a ROH of length 288 from position 94209055 to position 97356400 ( 3.15 Mb)
Chr 5 has a ROH of length 324 from position 36886836 to position 37437274 ( 0.55 Mb)
Chr 5 has a ROH of length 665 from position 111984920 to position 112302830 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 2121 from position 471038 to position 6453352 ( 5.98 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 223 from position 32703162 to position 32798091 ( 0.09 Mb)
Chr 6 has a ROH of length 3136 from position 124922347 to position 139526049 (14.60 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 7 has a ROH of length 314 from position 117058220 to position 117347082 ( 0.29 Mb)
Chr 7 has a ROH of length 589 from position 153674630 to position 155225328 ( 1.55 Mb)
Chr 8 has a ROH of length 289 from position 107844447 to position 109595712 ( 1.75 Mb)
Chr 9 has a ROH of length 4605 from position 77411218 to position 97017858 (19.61 Mb)
Chr 10 has a ROH of length 248 from position 89595652 to position 89868930 ( 0.27 Mb)
Chr 11 has a ROH of length 589 from position 16843716 to position 18745177 ( 1.90 Mb)
Chr 11 has a ROH of length 287 from position 63164238 to position 64572560 ( 1.41 Mb)
Chr 11 has a ROH of length 214 from position 108170444 to position 108206694 ( 0.04 Mb)
Chr 11 has a ROH of length 201 from position 111346465 to position 112434430 ( 1.09 Mb)
Chr 12 has a ROH of length 206 from position 9351648 to position 10281255 ( 0.93 Mb)
Chr 12 has a ROH of length 208 from position 49374476 to position 49609808 ( 0.24 Mb)
Chr 13 has a ROH of length 1312 from position 32904299 to position 32915413 ( 0.01 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 13 has a ROH of length 276 from position 52426514 to position 53346606 ( 0.92 Mb)
Chr 14 has a ROH of length 253 from position 23856987 to position 23892881 ( 0.04 Mb)
Chr 15 has a ROH of length 265 from position 48694211 to position 48764862 ( 0.07 Mb)
Chr 16 has a ROH of length 393 from position 2087562 to position 2232121 ( 0.14 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 16 has a ROH of length 332 from position 23607079 to position 23653020 ( 0.05 Mb)
Chr 17 has a ROH of length 1855 from position 41173086 to position 41353410 ( 0.18 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 18 has a ROH of length 3727 from position 22513179 to position 41906424 (19.39 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 542 from position 11210916 to position 11233940 ( 0.02 Mb)
Chr 22 has a ROH of length 405 from position 49420129 to position 50349644 ( 0.93 Mb)
Chr X has a ROH of length 307 from position 38203687 to position 38505492 ( 0.30 Mb)
Chr X has a ROH of length 220 from position 79128154 to position 82236712 ( 3.11 Mb)
Chr X has a ROH of length 484 from position 100559427 to position 102998081 ( 2.44 Mb)
Chr X has a ROH of length 403 from position 107448639 to position 108407096 ( 0.96 Mb)
Chr X has a ROH of length 232 from position 154066677 to position 154916845 ( 0.85 Mb) (1 heterozygous SNPs treated as homozygous)
Chr Y has a ROH of length 1668 from position 5682834 to position 58883690 (53.20 Mb) (4 heterozygous SNPs treated as homozygous)
mtDNA has a ROH of length 224 from position 515 to position 16391 ( 0.02 Mb)
Total ROH Mb: 154.57
Total genome Mb: 3154.06
The detected ROHs account for 4.901 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 70.850 % (35034 of 49448 SNPs) are homozygous, 61 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 69.506 % (37192 of 53509 SNPs) are homozygous, 74 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr 3: 69.137 % (29321 of 42410 SNPs) are homozygous, 56 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 67.375 % (24571 of 36469 SNPs) are homozygous, 49 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 67.588 % (25760 of 38113 SNPs) are homozygous, 55 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 6: 73.852 % (31370 of 42477 SNPs) are homozygous, 74 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 7: 69.767 % (23690 of 33956 SNPs) are homozygous, 41 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 67.425 % (21975 of 32592 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 73.191 % (21300 of 29102 SNPs) are homozygous, 33 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 67.443 % (21718 of 32202 SNPs) are homozygous, 45 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 70.641 % (22490 of 31837 SNPs) are homozygous, 30 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 69.204 % (21220 of 30663 SNPs) are homozygous, 38 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 70.943 % (17291 of 24373 SNPs) are homozygous, 36 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 14: 69.076 % (14345 of 20767 SNPs) are homozygous, 24 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 68.984 % (14399 of 20873 SNPs) are homozygous, 21 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 69.383 % (15818 of 22798 SNPs) are homozygous, 26 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 17: 73.154 % (16216 of 22167 SNPs) are homozygous, 19 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 18: 74.027 % (13863 of 18727 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 19: 70.897 % (11630 of 16404 SNPs) are homozygous, 27 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 66.849 % (11853 of 17731 SNPs) are homozygous, 16 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 66.640 % ( 6692 of 10042 SNPs) are homozygous, 11 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 68.609 % ( 7416 of 10809 SNPs) are homozygous, 5 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 75.638 % (18824 of 24887 SNPs) are homozygous, 29 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr Y: 1803 SNPs, 1735 No-Calls, 4 heterozygous SNPs treated as homozygous
Chr XY: 46 SNPs, 0 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 224 SNPs, 1 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 0.126 % ( 803 of 637469 SNPs) are NoCalls
Total autosomal (Chr 1-22): 30.167 % (192305 of 637469 SNPs) are Heterozygous (this tally excludes 12 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 69.833 % (445164 of 637469 SNPs) are Homozygous (this tally includes 12 heterozygous SNPs that were treated as homozygous)


23andme v5

ROHs of length at least 200 will be reported.
No-Call runs of length at least 10 will be reported.
No-Calls will be treated as homozygous.
Heterozygous SNPs that are at least 150 SNPs away from the nearest heterozygous SNP will be treated as homozygous.
Chr 9 has a No-Call run of length 10 from position 44766443 to position 44805175 (38.73 Kb)
Chr 21 has a No-Call run of length 12 from position 10748558 to position 10849946 (101.39 Kb)
Chr Y has a No-Call run of length 3733 from position 1726773 to position 58997092 (57270.32 Kb)

Chr 1 has a ROH of length 2083 from position 71020447 to position 82342336 (11.32 Mb)
Chr 1 has a ROH of length 228 from position 121355922 to position 144896319 (23.54 Mb)
Chr 1 has a ROH of length 224 from position 235062181 to position 236141259 ( 1.08 Mb)
Chr 2 has a ROH of length 391 from position 166606326 to position 166930062 ( 0.32 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 2 has a ROH of length 219 from position 179364778 to position 179486037 ( 0.12 Mb)
Chr 3 has a ROH of length 1578 from position 32777275 to position 39313391 ( 6.54 Mb)
Chr 3 has a ROH of length 397 from position 94182127 to position 97398548 ( 3.22 Mb)
Chr 3 has a ROH of length 212 from position 168593055 to position 169084827 ( 0.49 Mb)
Chr 5 has a ROH of length 262 from position 36833115 to position 37582130 ( 0.75 Mb)
Chr 6 has a ROH of length 1758 from position 466907 to position 6453352 ( 5.99 Mb)
Chr 6 has a ROH of length 211 from position 32713188 to position 32797876 ( 0.08 Mb)
Chr 6 has a ROH of length 3156 from position 124915655 to position 139529521 (14.61 Mb) (1 heterozygous SNPs treated as homozygous)
Chr 6 has a ROH of length 213 from position 140163298 to position 142027189 ( 1.86 Mb)
Chr 7 has a ROH of length 493 from position 153794933 to position 155225924 ( 1.43 Mb)
Chr 8 has a ROH of length 326 from position 107913227 to position 109601964 ( 1.69 Mb)
Chr 9 has a ROH of length 4345 from position 77398791 to position 97062295 (19.66 Mb)
Chr 10 has a ROH of length 209 from position 64205248 to position 65310986 ( 1.11 Mb)
Chr 11 has a ROH of length 549 from position 16843716 to position 18746427 ( 1.90 Mb)
Chr 11 has a ROH of length 338 from position 63171313 to position 64590854 ( 1.42 Mb)
Chr 12 has a ROH of length 224 from position 9318694 to position 10321383 ( 1.00 Mb)
Chr 12 has a ROH of length 208 from position 56076266 to position 56878301 ( 0.80 Mb)
Chr 13 has a ROH of length 542 from position 32890583 to position 32919384 ( 0.03 Mb)
Chr 13 has a ROH of length 211 from position 32944547 to position 33175434 ( 0.23 Mb)
Chr 14 has a ROH of length 205 from position 23840033 to position 23902297 ( 0.06 Mb)
Chr 16 has a ROH of length 206 from position 32581849 to position 46538405 (13.96 Mb)
Chr 17 has a ROH of length 600 from position 41143775 to position 41448680 ( 0.30 Mb)
Chr 18 has a ROH of length 3576 from position 22517480 to position 41967979 (19.45 Mb) (2 heterozygous SNPs treated as homozygous)
Chr 19 has a ROH of length 228 from position 11210898 to position 11234021 ( 0.02 Mb)
Chr 22 has a ROH of length 386 from position 49417110 to position 50417824 ( 1.00 Mb)
Chr X has a ROH of length 223 from position 100559427 to position 103359175 ( 2.80 Mb)
Chr Y has a ROH of length 3733 from position 1726773 to position 58997092 (57.27 Mb)
Total ROH Mb: 194.07
Total genome Mb: 3007.10
The detected ROHs account for 6.454 % of the reported genome.

The following percentages are for individual homozygous SNPs, not just those in ROHs.

Chr 1: 84.478 % (41825 of 49510 SNPs) are homozygous, 1200 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 2: 83.537 % (43248 of 51771 SNPs) are homozygous, 1046 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 3: 83.876 % (36086 of 43023 SNPs) are homozygous, 941 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 4: 83.143 % (32819 of 39473 SNPs) are homozygous, 878 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 5: 83.494 % (30916 of 37028 SNPs) are homozygous, 790 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 6: 84.548 % (37219 of 44021 SNPs) are homozygous, 876 No-Calls, 1 heterozygous SNPs treated as homozygous
Chr 7: 84.014 % (28864 of 34356 SNPs) are homozygous, 849 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 8: 82.870 % (26254 of 31681 SNPs) are homozygous, 620 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 9: 85.400 % (22584 of 26445 SNPs) are homozygous, 682 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 10: 82.570 % (25202 of 30522 SNPs) are homozygous, 651 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 11: 83.870 % (25952 of 30943 SNPs) are homozygous, 604 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 12: 82.944 % (24412 of 29432 SNPs) are homozygous, 661 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 13: 83.293 % (18391 of 22080 SNPs) are homozygous, 368 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 14: 82.852 % (16538 of 19961 SNPs) are homozygous, 462 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 15: 83.016 % (15778 of 19006 SNPs) are homozygous, 421 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 16: 82.810 % (16890 of 20396 SNPs) are homozygous, 489 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 17: 84.099 % (16316 of 19401 SNPs) are homozygous, 504 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 18: 85.917 % (15185 of 17674 SNPs) are homozygous, 284 No-Calls, 2 heterozygous SNPs treated as homozygous
Chr 19: 82.371 % (12256 of 14879 SNPs) are homozygous, 561 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 20: 81.165 % (11997 of 14781 SNPs) are homozygous, 298 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 21: 82.061 % ( 7063 of 8607 SNPs) are homozygous, 221 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr 22: 84.083 % ( 7496 of 8915 SNPs) are homozygous, 271 No-Calls, 0 heterozygous SNPs treated as homozygous

Chr X: 76.509 % (12647 of 16530 SNPs) are homozygous, 544 No-Calls, 0 heterozygous SNPs treated as homozygous
Chr Y: 3733 SNPs, 3733 No-Calls, 0 heterozygous SNPs treated as homozygous
mtDNA : 4305 SNPs, 323 No-Calls, 0 heterozygous SNPs treated as homozygous

Total autosomal (Chr 1-22): 2.228 % ( 13677 of 613905 SNPs) are NoCalls
Total autosomal (Chr 1-22): 16.389 % (100614 of 613905 SNPs) are Heterozygous (this tally excludes 4 heterozygous SNPs that were treated as homozygous)
Total autosomal (Chr 1-22): 83.611 % (513291 of 613905 SNPs) are Homozygous (this tally includes 4 heterozygous SNPs that were treated as homozygous)

In my experience Ancestry might be more accurate than 23andme.
Total number of ROH segments from your ancestry kit equal 33 with a corresponding total length of 154.57Mb. It fits quite well on the graph I shared of South/Central Asians among some Sindhis and Makranis and is not extremely shifted pointing to low recent events of endogamy, as compared to the South/Central Asians. Similarly you're 4.9% of region of genome that is homozygous is on the lower limit of some of the Azad Kashmiri population FROH scores in the figure above.
As Zack pointed out in his blog, non endogamous events (non-close kin marriages) in a single generation can change ROH. https://www.zackvision.com/weblog/20...le-generation/

[Kapisa]

You’re gonna have to teach me this lol

If you go on this website and plug in your unzipped DNA test results in txt format, it will calculate for you regions of your chromosome that both your parents have in common. If large segments are present, that points to endogamy or marriages among close kin.

https://www.math.mun.ca/~dapike/FF23utils/roh.php