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Thread: A genome sequence from a modern human skull >45,000 years old from Zlatý kůň Czechia

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    A genome sequence from a modern human skull >45,000 years old from Zlatý kůň Czechia

    A genome sequence from a modern human skull over 45,000 years old from Zlatý kůň in Czechia
    Kay Prüfer, Cosimo Posth, He Yu, Alexander Stoessel, Maria A. Spyrou, Thibaut Deviese, Marco Mattonai, Erika Ribechini, Thomas Higham, Petr Velemínský, Jaroslav Brůžek & Johannes Krause

    Abstract
    Modern humans expanded into Eurasia more than 40,000 years ago following their dispersal out of Africa. These Eurasians carried ~2–3% Neanderthal ancestry in their genomes, originating from admixture with Neanderthals that took place sometime between 50,000 and 60,000 years ago, probably in the Middle East. In Europe, the modern human expansion preceded the disappearance of Neanderthals from the fossil record by 3,000–5,000 years. The genetic makeup of the first Europeans who colonized the continent more than 40,000 years ago remains poorly understood since few specimens have been studied. Here, we analyse a genome generated from the skull of a female individual from Zlatý kůň, Czechia. We found that she belonged to a population that appears to have contributed genetically neither to later Europeans nor to Asians. Her genome carries ~3% Neanderthal ancestry, similar to those of other Upper Palaeolithic hunter-gatherers. However, the lengths of the Neanderthal segments are longer than those observed in the currently oldest modern human genome of the ~45,000-year-old Ust’-Ishim individual from Siberia, suggesting that this individual from Zlatý kůň is one of the earliest Eurasian inhabitants following the expansion out of Africa.


    Oldest DNA from a Homo sapiens reveals surprisingly recent Neanderthal ancestry
    Ancient human lineages interbred commonly in Europe, as well as the Middle East.
    Ewen Callaway
    in Nature.


    So far, the oldest genome of modern humans reconstructed
    A team from two Max Planck Institutes and the University of Tübingen dates fossil skulls from the Czech Republic using crossed Neanderthal genes - an age of more than 45,000 years
    Press Release from Max Planck Institute, there's a nice video on the web page.


    More than 45,000 years ago, modern humans ventured into Neanderthal territory. Here’s what happened next
    By Ann Gibbons
    in Science
    Last edited by pmokeefe; 04-07-2021 at 07:04 PM. Reason: added link to published paper and abstract
    YFull: YF14620 (Dante Labs 2018)

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    Quote Originally Posted by davit View Post
    ydina?
    Zlaty Kun is a woman.
    Immi uiros rios toutias rias
     
    ___ Paper trail since 1550 : 100% South Auvergne, France ___
    Distance: 1.510% : 50.0 German , 50.0 Spanish Castilla .... Distance: 1.453% : 50.4 Swiss German , 49.6 Spanish Barcelona
    Distance: 1.659% : 50.2 Scottish , 49.8 French Corsica...... Distance: 1.714% : 50.8 Italian Lombardy , 49.2 French Brittany
    Distance: 1.959% : 50.8 Irish , 49.2 Italian Tuscany ......... Distance: 2.189% : 50.8 Dutch , 49.2 Basque French

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    J. Krause in the video at 4:48, claims the sample is basal to the East/West Eurasian split:
    https://vimeo.com/525618213
    YFull: YF14620 (Dante Labs 2018)

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    Quote Originally Posted by pmokeefe View Post
    J. Krause in the video at 4:48, claims the sample is basal to the East/West Eurasian split:
    https://vimeo.com/525618213


    Nice seeing a qpGraph modeled with an OoA specimen considered possibly even older than Ust'-Ishim.

    - it's interesting to think how many other ancient samples have been misleadingly misdated due to similar carbon-dating issues (mentioned in the clip) -- thankfully, Zlatý kůň was re-calibrated

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    Article
    Open Access
    Published: 07 April 2021
    A genome sequence from a modern human skull over 45,000 years old from Zlatý kůň in Czechia

    https://www.nature.com/articles/s41559-021-01443-x

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    Well ain't that a doozy, Zlaty Kun basal to Ust-East-West split?
    Maybe helps explain something I've been seeing alot running qpgraph, where BachoKiro_IUP keeps taking 50-75% of an edge right about the depth Zlaty Kun is branching there.
    BachoKiro_IUP = Zlaty Kun + X
    Tianyuan = East-Eurasian + X
    Maybe? I'd love to have the genotype data of Zlaty Kun to test that.
    Collection of 14,000 d-stats: Hidden Content Part 2: Hidden Content Part 3: Hidden Content PM me for d-stats, qpadm, qpgraph, or f3-outgroup nmonte models.

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    There are many African Y chromosome haplogroups derived from Eurasia, though mtDNA not as many. The ancestral African men won't not to carry their own DNA to Africa, though mostly washed by local mtDNA carrier. I don't think there hardly any Neanderthal or Denisovan DNA in nowadays African. And for Homo naledi is uniquely only 200-300 ky bp, and seems had funeral practices like Neanderthals and sapiens, I don't think there are no archaic humanoid DNA sections in present day African genomes. This is clearly a bug in the OOA theory, why nearly everyone ignores this?

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    So extinction of the Zlatý kun kind would have preceded that of the Neanderthals?

    We now have Ust'Ishim, Zlatý kun and Oase1 as representatives of populations that are unrelated to people that lived after 40kya. Maybe groups were relatively small and isolated during the IUP? Perhaps these OOA-migrants weren't fully adapted to the Eurasian environments yet?

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    Quote Originally Posted by Milkyway View Post
    So extinction of the Zlatý kun kind would have preceded that of the Neanderthals?

    We now have Ust'Ishim, Zlatý kun and Oase1 as representatives of populations that are unrelated to people that lived after 40kya. Maybe groups were relatively small and isolated during the IUP? Perhaps these OOA-migrants weren't fully adapted to the Eurasian environments yet?
    It's such a pity Oase 2 isn't published yet. But at least we know it forms a population with Oase 1. Not with Ust'Ishim though.

    EDIT: Even that last sentence isn't straight forward.
    Last edited by epoch; 04-08-2021 at 04:22 PM.

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