Results 1 to 3 of 3

Thread: 23andMe V5 Conversion

  1. #1
    Gold Class Member
    Posts
    529
    Sex
    Ethnicity
    Jew
    Nationality
    USA
    Y-DNA (P)
    I-BY424 (Z26381+)
    mtDNA (M)
    H7c2
    Y-DNA (M)
    E-CTS5265
    mtDNA (P)
    K1a9

    Israel Israel Jerusalem Ukraine Uzbekistan Star of David

    23andMe V5 Conversion

    Is anyone here able to convert 23andMe V5 into a hg19/hg37 format? I have three files in need of conversion. Thank you.
    23andMe 5.9:
    100% Ashkenazi Jewish

    Eurogenes K13:
    East_Med 44
    West_Med 19.15
    North_Atlantic 15.63
    West_Asian 8.15
    Baltic 4.47
    Red_Sea 4.12
    East_Asian 1.31
    Sub-Saharan 1.23
    South Asian 0.71
    Amerindian 0.59
    Northeast_African 0.37
    Oceanian 0.27

    Father 23andMe 5.9:
    100% Ashkenazi Jewish

    Mother 23andMe 5.9:
    98.4% Ashkenazi Jewish
    0.5% Iranian, Caucasian, Mesopotamian
    0.5% Levantine
    0.2% Coptic Egyptian
    0.2% Sudanese
    0.2% Ethiopian & Eritrean

  2. #2
    Gold Class Member
    Posts
    529
    Sex
    Ethnicity
    Jew
    Nationality
    USA
    Y-DNA (P)
    I-BY424 (Z26381+)
    mtDNA (M)
    H7c2
    Y-DNA (M)
    E-CTS5265
    mtDNA (P)
    K1a9

    Israel Israel Jerusalem Ukraine Uzbekistan Star of David
    Quote Originally Posted by Palki View Post
    hg19 is not a format ? its a reference genome , do you mean V3 format ?
    they say that all there chip versions used hg19 reference
    https://customercare.23andme.com/hc/...s-23andMe-Use-
    I didn't see anything on that link about hg19, but I was told v5 uses hg38 reference so I would need conversion to something like a hg37 reference, I suppose v3 would work.
    23andMe 5.9:
    100% Ashkenazi Jewish

    Eurogenes K13:
    East_Med 44
    West_Med 19.15
    North_Atlantic 15.63
    West_Asian 8.15
    Baltic 4.47
    Red_Sea 4.12
    East_Asian 1.31
    Sub-Saharan 1.23
    South Asian 0.71
    Amerindian 0.59
    Northeast_African 0.37
    Oceanian 0.27

    Father 23andMe 5.9:
    100% Ashkenazi Jewish

    Mother 23andMe 5.9:
    98.4% Ashkenazi Jewish
    0.5% Iranian, Caucasian, Mesopotamian
    0.5% Levantine
    0.2% Coptic Egyptian
    0.2% Sudanese
    0.2% Ethiopian & Eritrean

  3. #3
    Gold Class Member
    Posts
    464
    Sex
    Y-DNA (P)
    R-Y33
    mtDNA (M)
    J1c2
    Y-DNA (M)
    E-Y6938
    mtDNA (P)
    G2a

    Russian Federation Russia Tatarstan Arms Russia Mordovia Timurid
    V3/V5 refers to versions of the Illumina SNP and has nothing to do with the human reference genome version. 23andMe is still using the hg19/GRCh37 build, even for those who tested with V5. Here's what the header from my raw data files says (I tested with the V5 chip).

    # We are using reference human assembly build 37 (also known as Annotation Release 104).
    # Note that it is possible that data downloaded at different times may be different due to ongoing
    # improvements in our ability to call genotypes. More information about these changes can be found at:
    # https://you.23andme.com/p/346a71bba9...data/download/
    #
    # More information on reference human assembly builds:
    # https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/
    YDNA (P): R-Y33
    YDNA (P, maternal line): R-Y20756
    YDNA(M): E-Y6938

  4. The Following 2 Users Say Thank You to altvred For This Useful Post:

     jkotl0327 (06-24-2021),  Palki (06-24-2021)

Similar Threads

  1. Conversion of 23andme V5 to V3 format VCF
    By Ayetooey in forum General
    Replies: 0
    Last Post: 04-05-2021, 07:17 PM
  2. 23andMe Kit Conversion
    By StillWater in forum 23andMe
    Replies: 6
    Last Post: 03-07-2020, 03:16 AM
  3. Replies: 0
    Last Post: 09-25-2016, 09:13 AM
  4. Replies: 10
    Last Post: 03-28-2016, 10:53 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •